9 completed, 3 unknown, 2 recruiting, 2 terminated. 18 Phase 1, 10 Phase 2.
Follow PRP: new trials by email Literature Review of PRP trials Research Report on PRP
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Regenerative Medicine for Joint Hypermobility and Instability Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational) - Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS) | Phase 1 / Phase 2 | Not yet recruiting | Manhattan Pain Medicine, PLLC | 100 | 2027-01-15 | 2026-10-06 |
| Evaluating Mechanically Engineered Stem Cell Exosomes for Treating Endometrial Injury: A Clinical Study Mechanically Engineered Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes, Umbilical cord mesenchymal stem cell-derived exosomes, platelet-rich plasma - Thin Endometrial Lining, Female Infertility | Phase 1 / Phase 2 | Recruiting | Tang-Du Hospital | 90 | 2025-02-21 | 2025-03-26 |
| Subtenon Autologous Platelet-Rich Plasma in Inherited and Degenerative Retinal Diseases Subtenon Injection of Autologous Platelet-Rich Plasma - Extensive Macular Atrophy With Pseudodrusen (EMAP), Retinitis Pigmentosa (RP) | Phase 1 / Phase 2 | Active not recruiting | Rubens Camargo Siqueira | 30 | 2025-01-04 | 2026-07-01 |
| Safety and Preliminary Efficacy of iEVs Injection in Treating Lateral Epicondylitis of Humerus iEV, PRP, immobilization - Lateral Epicondylitis | Phase 1 / Phase 2 | Recruiting | Shanghai 6th People's Hospital | 24 | 2023-07-01 | 2025-08-08 |
| Biological Response to Platelet-rich Plasma and Corticosteroid Injections Triamcinolone Acetonide 40 mg/ml Inj, Susp, Platelet-rich plasma Inj - Knee Osteoarthritis | Phase 1 / Phase 2 | Terminated | University of Missouri-Columbia | 23 | 2022-12-28 | 2025-06-25 |
| The Effect of Platelet Rich Plasma (PRP) Application on Rotator Cuff Tear. Platelet Rich Plasma, Normal saline - Tendon Injuries, Supraspinatus Injury | Phase 1 | Completed | Aristotle University Of Thessaloniki | 40 | 2022-12-23 | 2026-03-06 |
| Effectiveness of PRP, Conditioned Medium UC-MSCs Secretome and Hyaluronic Acid for the Treatment of Knee Osteoarthritis Platelet-rich Plasma, Conditioned Medium From Umbilical Cord Mesenchymal Stem Cell Culture (MSCs) Secretome, Low Molecular Weight Hyaluronic Acid - Knee Osteoarthritis | Phase 1 / Phase 2 | Completed | Universitas Sriwijaya | 45 | 2022-10-02 | 2026-05-22 |
| Treatment Outcome of Autologous PRP Versus Conventional Therapy Among Patients With Chronic Venous Leg Ulcers PRP, Conventional therapy - Venous Leg Ulcer | Phase 1 | Completed | Jinnah Postgraduate Medical Centre | 48 | 2022-09-01 | 2023-08-03 |
| Platelet Rich Plasma for the Treatment of Genitourinary Syndrome of Menopause in Patients With Stage 0-III Breast Cancer Quality-of-Life Assessment, Questionnaire Administration, Therapeutic Autologous Platelet-rich Plasma - Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | Phase 1 | Completed | Mayo Clinic | 20 | 2020-09-23 | 2024-04-03 |
| IA Injection of Rejoint Gel and PRP in Patients With Unilateral Knee OA PRP - PRP, Knee Osteoarthritis | Phase 1 | Unknown | National Taiwan University Hospital | 30 | 2020-08-13 | 2020-08-24 |
| The Effects of Platelet-Rich Plasma Versus Prolotherapy On Rotator Cuff Tendinopathy: A Randomized Controlled Trial. Platelet-Rich Plasma, Prolotherapy - Rotator Cuff Tendinosis, Supraspinatus Strain | Phase 1 | Completed | University of Malaya | 60 | 2020-02-17 | 2022-11-02 |
| Efficacy of Platelet Enriched Plasma in Preventing Surgery for Patients With Chronic Tympanic Membrane Perforation Platelet Rich Plasma - Tympanic Membrane Perforation | Phase 1 / Phase 2 | Terminated | University of Kansas Medical Center | 1 | 2018-05-02 | 2024-07-16 |
| Platelet-Rich Plasma (PRP) Injection in Treatment of Interstitial Cystitis Platelet-Rich Plasma - Interstitial Cystitis | Phase 1 | Unknown | Buddhist Tzu Chi General Hospital | 30 | 2017-04-01 | 2017-04-07 |
| Using Platelet Rich Plasma in Reducing Alveolar Bone Resorption During Rapid Maxillary Expansion Platelet Rich Plasma, No Platelet Rich Plasma - Bone Resorption | Phase 1 | Completed | Damascus University | 16 | 2016-07-01 | 2018-07-30 |
| PRP Gel in Wound Closure in Recurrent CS platelet rich plasma gel, saline - Previous Incision, Scar; Previous Cesarean Section | Phase 1 / Phase 2 | Completed | Ain Shams University | 128 | 2016-04-01 | 2017-05-16 |
| Mesenchymal Stem Cells Enhanced With PRP Versus PRP In OA Knee Mesenchymal stem cell suspension, PRP - Osteoarthritis, Knee | Phase 1 / Phase 2 | Unknown | Aditya K Aggarwal | 24 | 2013-01-01 | 2013-11-18 |
| Efficacy & Safety Trial of Intravitreal Injections Combined With PRP for CSME Secondary to Diabetes Mellitus (DAVE) 0.3 mg ranibizumab, Targeted Pan Retinal Photocoagulation - Diabetic Macular Edema | Phase 1 / Phase 2 | Completed | David M. Brown, M.D. | 29 | 2012-03-01 | 2018-10-05 |
| A Pilot Study for the Treatment of Iris Neovascularization With Macugen Pegaptanib Sodium Injection/Panretinal Photocoagulation, Panretinal Photocoagulation (PRP) - Iris Neovascularization, Diabetic Retinopathy | Phase 1 | Completed | Hermann Eye Center | 10 | 2006-01-01 | 2008-09-04 |
Osteoarthritis, Knee (4) · Diabetic Retinopathy (2) · Osteoarthritis (2) · Alveolar Bone Loss (1) · Anetoderma (1) · Bone Resorption (1) · Breast Carcinoma In Situ (1) · Cicatrix (1) · Cystitis, Interstitial (1) · Ehlers-Danlos Syndrome (1) · Ehlers-Danlos syndrome type 3 (1) · Gynatresia (1) · Hearing Loss (1) · Infertility, Female (1) · Joint Dislocations (1)
Aditya K Aggarwal (1) · Ain Shams University (1) · Aristotle University Of Thessaloniki (1) · Buddhist Tzu Chi General Hospital (1) · Damascus University (1) · David M. Brown, M.D. (1) · Hermann Eye Center (1) · Jinnah Postgraduate Medical Centre (1) · Manhattan Pain Medicine, PLLC (1) · Mayo Clinic (1) · National Taiwan University Hospital (1) · Rubens Camargo Siqueira (1) · Shanghai 6th People's Hospital (1) · Tang-Du Hospital (1) · Universitas Sriwijaya (1)
United States (5) · China (2) · Taiwan (2) · Brazil (1) · Egypt (1) · Greece (1) · India (1) · Indonesia (1) · Malaysia (1) · Pakistan (1) · Syria (1)
Aditya K Aggarwal, MS,DNB,DO (1) · Anita H. Chen, M.D. (1) · Byron Chalidis, PhD (1) · Charalampos Pitsilos, MSc (1) · Chueh-Hung Wu, MD, PhD (1) · David M Brown, MD (1) · Hinrich Staecker, MD (1) · Ioannis Gigis, PhD (1) · Jason Siefferman, MD (1) · Kinda Sultan, MSc, PhD (1) · Mariia Safroshkina, MD (1) · Pericles Papadopoulos, PhD (1) · Rabia Ghafoor (1)
PMID 15039276, PMID 18587624, PMID 23559821, PMID 23671833, PMID 23763951, PMID 24910679, PMID 25005628, PMID 25035839, PMID 25171042, PMID 25446135, PMID 25478739, PMID 25490552, PMID 25722595, PMID 26124033, PMID 26367495, PMID 26390274, PMID 28287489, PMID 30920874, PMID 31000394, PMID 31901394, PMID 32181337, PMID 32551947, PMID 32939046, PMID 34505846, PMID 34711824, PMID 34945097, PMID 36089055, PMID 36369425, PMID 38588501, PMID 39643206, PMID 40966714, PMID 42193355