7 completed, 1 not yet recruiting, 1 unknown. 9 Phase 2, 3 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 7, Not yet recruiting 1, Unknown 1 |
| Phase 3 | 3 | Completed 3 |
| Phase 1 | 1 | Completed 1 |
Follow Propolis: new trials by email Literature Review of Propolis trials Research Report on Propolis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Propolis-Based Solution Application in Extraction Socket Healing Propolis-based topical solution (52% propolis extract, clove oil [Eugenia caryophyllus], and white willow bark [Salix alba] extract), Saline rinse (control) - Healthy | Phase 1 / Phase 2 | Completed | Saint-Joseph University | 14 | 2025-10-01 | 2026-06-29 |
| Propolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients propolis, chlorohexidine mouthwash and topical antifungal - Oral Mucositis Due to Chemotherapy | Phase 2 | Not yet recruiting | Ain Shams University | 50 | 2025-07-15 | 2025-07-18 |
| Brazilian Green Propolis Extract (EPP-AF) as an Adjunct Treatment for Hospitalized COVID-19 Patients (BeeCovid2) Standardized Brazilian Green Propolis Extract, Placebo - Covid19, Inflammation | Phase 2 / Phase 3 | Completed | D'Or Institute for Research and Education | 200 | 2021-04-12 | 2022-05-13 |
| Propolis as a Treatment Option for Hand Foot and Mouth Disease Propolis - Children Diagnosed With HMFD, Propolis Antiviral Activity | Phase 2 / Phase 3 | Completed | Murat Sutcu | 200 | 2019-01-01 | 2024-06-12 |
| Comparison Of The Effect Of Propolis And Gluma Desensitizer On The Management Of Dentin Hypersensitivity Propolis, Gluma Desensitizer - Dentin Hypersensitivity | Phase 2 / Phase 3 | Completed | Dow University of Health Sciences | 40 | 2018-12-16 | 2021-03-29 |
| Postoperative Pain Evaluation of Mineral Trioxide Aggregate and Propolis After Pulpotomy in Carious Primary Molars Propolis, Mineral Trioxide Aggregate - Pulp Disease, Dental | Phase 2 | Unknown | Cairo University | 28 | 2018-11-01 | 2019-07-29 |
| Effect of Propolis or Metformin Administration on Glycemic Control in Patients With Type 2 Diabetes Mellitus Propolis, Metformin, Placebo - Diabetes Mellitus, Type 2 | Phase 2 | Completed | University of Guadalajara | 36 | 2018-01-30 | 2022-11-07 |
| Propolis Effects in Patients With Chronic Kidney Disease Propolis, Placebo - Chronic Kidney Diseases | Phase 2 | Completed | University of Sao Paulo General Hospital | 32 | 2016-12-01 | 2018-05-03 |
| Assessing the Preventing and Therapeutic Effect of Propolis in Radiotherapy Induced Mucositis of Head and Neck Cancers propolis - Radiation-induced Mucositis of Oral Mucous Membranes | Phase 2 | Completed | Mashhad University of Medical Sciences | 20 | 2010-10-01 | 2012-11-22 |
COVID-19 (1) · Dental Pulp Diseases (1) · Dentin Sensitivity (1) · Diabetes Mellitus, Type 2 (1) · Inflammation (1) · Mucositis (1) · Neoplasms (1) · Proteinuria (1) · Renal Insufficiency, Chronic (1)
Ain Shams University (1) · Cairo University (1) · D'Or Institute for Research and Education (1) · Dow University of Health Sciences (1) · Mashhad University of Medical Sciences (1) · Murat Sutcu (1) · Saint-Joseph University (1) · University of Guadalajara (1) · University of Sao Paulo General Hospital (1)
Brazil (2) · Egypt (2) · Iran (1) · Lebanon (1) · Mexico (1) · Pakistan (1) · Turkey (Türkiye) (1)
Marcelo Silveira, MD, PhD (1) · Marina Shah, BDS (1)
PMID 15660575, PMID 17167116, PMID 21965377, PMID 23320022, PMID 25607548, PMID 31023272, PMID 35379306, PMID 37891178, PMID 37916745, PMID 38783427