325 completed, 122 unknown, 47 terminated, 31 withdrawn. 188 Phase 2, 152 Phase 3, 110 Phase 4, 69 Phase 1, 68 Not applicable.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Study of BAT4406F Injection in Patients With Minimal Change Disease/Focal Segmental Glomerulosclerosis BAT4406F, Placebos - Minimal Change Disease (MCD), Focal Segmental Glomerulosclerosis (FSGS) | Phase 2 / Phase 3 | Recruiting | Bio-Thera Solutions | 192 | 2025-10-26 | 2026-04-03 |
| Rectal Indomethacin as Early Treatment for Acute Pancreatitis (INDOMAP Trial) Indomethacin SR, Placebos - Acute Pancreatitis, Complication | Phase 4 | Recruiting | Peking Union Medical College Hospital | 1504 | 2024-12-01 | 2025-06-15 |
| A Two-Part Phase 2a Study of RVX000222 in Patients With End-Stage Renal Disease Treated With Hemodialysis apabetalone, Placebos - Kidney Failure, Chronic | Phase 1 / Phase 2 | Not yet recruiting | Resverlogix Corp | 44 | 2024-11-22 | 2023-11-15 |
| The Effects of Metformin on Morbidity and Mortality in Elderly Patients Metformin, Placebos - Burns | Phase 2 | Not yet recruiting | Hamilton Health Sciences Corporation | 250 | 2024-11-01 | 2024-10-02 |
| Age Differences in the Effects of Cannabis on Simulated Driving Cannabis, Placebos - Cannabis | Not applicable | Recruiting | Centre for Addiction and Mental Health | 128 | 2024-03-27 | 2026-03-23 |
| Nabilone Use For Acute Pain in Inflammatory Bowel Disease Patients Nabilone, Placebos - Inflammatory Bowel Diseases | Not applicable | Unknown | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | 80 | 2023-12-01 | 2023-06-07 |
| Nitric Oxide Donor Isosorbide Mono Nitrate for Cervical Ripening in Induction of Labor isosorbide mononitrate, Placebos - Induction of Labor Affected Fetus / Newborn | Phase 4 | Completed | ahmed nagy shaker ramadan | 160 | 2023-12-01 | 2024-08-22 |
| Immunomodulatory Effect of Macrolides in Naturally Occurring Influenza Virus Infections in the Community Clarithromycin 250 MG, Placebos - Influenza, Human | Phase 4 | Suspended | The University of Hong Kong | 100 | 2023-06-01 | 2022-11-04 |
| Efficacy of Phosphodiesterase-type 5 Inhibitors in Patients With Univentricular Congenital Heart Disease Sildenafil, Placebos - Single-ventricle, Pulmonary Hypertension | Phase 3 | Withdrawn | University Hospital, Montpellier | 2023-06-01 | 2023-05-15 | |
| Combination of Methotrexate and Phototherapy Versus Phototherapy in Adults With Progressive Vitiligo Methotrexate, Placebos - Vitiligo | Phase 2 | Completed | University Hospital, Bordeaux | 32 | 2023-05-23 | 2026-05-22 |
| Dexmedetomidine and HIPEC Dexmedetomidine, Placebos - Inflammation, Cancer | Phase 2 / Phase 3 | Unknown | University of British Columbia | 20 | 2023-03-01 | 2022-11-03 |
| Phase II Clinical Trial of Clenbuterol in Adult Patients With Pompe Disease Clenbuterol, Placebos - Pompe Disease (Late-onset) | Phase 2 | Withdrawn | Duke University | 2023-01-01 | 2022-08-17 | |
| Fracture Recovery for Returning to Duty (Teriparatide STRONG) Teriparatide, Placebos - Stress Fracture of Tibia or Fibula | Phase 4 | Enrolling by invitation | University of South Carolina | 183 | 2022-12-08 | 2023-02-13 |
| A Study to Evaluate the Efficacy and Safety of HR18042 Tablets for Postoperative Analgesia After Impacted Teeth Removal Surgery. HR18042 tablets, Tramadol hydrochloride SR Tablets, Placebos - Pain | Phase 2 | Terminated | Jiangsu HengRui Medicine Co., Ltd. | 110 | 2022-08-11 | 2025-06-26 |
| Tranexamic Acid to Reduce Infection After Gastrointestinal Surgery Tranexamic Acid, Placebos - Infection Wound, Gastrointestinal Complication | Phase 4 | Completed | Bayside Health | 3300 | 2022-05-18 | 2025-12-31 |
| The Effects of Gut Micribiota Disruption on the Immune Response After Open Heart Surgery Vancomycin Oral, Metronidazole Oral, Ciprofloxacin Pill - Systemic Inflammatory Response Syndrome, Postoperative Shock | Not applicable | Unknown | Radboud University Medical Center | 80 | 2022-03-01 | 2021-03-12 |
| Inflammation and Daily Life Study Naproxen, Placebos - Inflammation | Early Phase 1 | Completed | University of California, Los Angeles | 144 | 2022-02-09 | 2025-02-25 |
| Maqui Berry Extract and Omega-3 Fatty Acids for Cytokine Reduction Maqui berry/omeg-3 fatty acids, Placebos - Inflammation | Not applicable | Completed | Arizona State University | 32 | 2022-01-15 | 2023-10-17 |
| Angiotensin-(1,7) Treatment in COVID-19: the ATCO Trial Angiotensin 1-7, Placebos - Coronavirus, Respiratory Failure | Phase 2 / Phase 3 | Unknown | Erasme University Hospital | 60 | 2021-12-30 | 2021-08-02 |
| Duloxetine RCT on Postop TKA Outcomes Duloxetine, Placebos - Pain, Postoperative, Total Knee Arthroplasty | Phase 4 | Completed | Rush University Medical Center | 241 | 2021-11-01 | 2025-11-14 |
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Pain (15) · Pain, Postoperative (12) · COVID-19 (11) · Depression (9) · Asthma (8) · Heart Failure (8) · Inflammation (8) · Diabetes Mellitus, Type 2 (7) · Non-alcoholic Fatty Liver Disease (7) · Obesity (7) · Breast Neoplasms (6) · Dermatitis, Atopic (6) · Insulin Resistance (6) · Schizophrenia (6) · Acute Pain (5)
Johns Hopkins University (5) · Mayo Clinic (5) · CHU de Quebec-Universite Laval (4) · Imperial College London (4) · Jiangsu HengRui Medicine Co., Ltd. (4) · Otsuka Pharmaceutical Co., Ltd. (4) · Shijiazhuang Yiling Pharmaceutical Co. Ltd (4) · Vanderbilt University Medical Center (4) · Yale University (4) · Assiut University (3) · Azienda Ospedaliero Universitaria Maggiore della Carita (3) · Beth Israel Deaconess Medical Center (3) · Dongzhimen Hospital, Beijing (3) · Fakultas Kedokteran Universitas Indonesia (3) · Icahn School of Medicine at Mount Sinai (3)
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Osamu Sato (3) · Antonio Abbate, MD, PhD (2) · Deven V Parmar, MD,FACP,FCP (2) · Fernand Labrie, MD, PhD (2) · James Murrough, MD, PhD (2) · Jinzhou Tian, M.D,PhD (2) · Leonello Cusan, MD, PhD (2) · Ming Shi, MD (2) · Paul C Cremer, M. D. (2) · Phyllis Zee, MD, PhD (2) · Sergei A Kharitonov, MD PhD (2) · Wen Ouyang, MD (2) · Abdelrhman Alshawadfy, M.D (1)
PMID 31609882, PMID 31791824, PMID 33754144, PMID 10427152, PMID 10811917, PMID 11726775, PMID 12050214, PMID 14581124, PMID 14622184, PMID 16363316, PMID 16450381, PMID 16563625, PMID 16611468, PMID 16645457, PMID 16873343, PMID 16984654, PMID 17123867, PMID 17138963, PMID 17157479, PMID 17485450, PMID 17492050, PMID 17550932, PMID 17603035, PMID 18359622, PMID 18574361, PMID 18719059, PMID 19233423, PMID 19375022, PMID 19700350, PMID 19720908, PMID 19858734, PMID 19917989, PMID 20012748, PMID 20117132, PMID 20417240, PMID 20506391, PMID 20626389, PMID 20739336, PMID 21300635, PMID 21471961, PMID 21477680, PMID 21565796, PMID 21795981, PMID 21903370, PMID 21910367, PMID 21920241, PMID 21920242, PMID 21963104, PMID 21963186, PMID 21981277
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