8 completed, 3 terminated, 1 recruiting, 1 unknown. 3 Not applicable, 3 Phase 1, 3 Phase 2, 3 Phase 4, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Terminated 2, Completed 1 |
| Phase 1 | 3 | Completed 2, Unknown 1 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Phase 4 | 3 | Completed 2, Withdrawn 1 |
| Early Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Pindolol: new trials by email Literature Review of Pindolol trials Research Report on Pindolol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Psilocybin Administration With 5-HT1a Blockade Pindolol, Placebo, Psilocybin - Psychedelic Effects in Healthy Volunteers | Early Phase 1 | Recruiting | Johns Hopkins University | 18 | 2026-08-12 | 2026-09-14 |
| Study of Comparative Bioavailability and Pharmacokinetics of ACM-001.1) and Pindolol in Healthy Volunteers (HV) Part 1 Group 1 Regime A (ACM-001.1), Part 1 Group 2 Regimen C (Pindolol), Part 2 Group D (Pindolol) - Cachexia | Phase 1 | Completed | Actimed Therapeutics Ltd | 51 | 2021-11-26 | 2023-10-10 |
| Impact of Beta-blockers on Physical Function in HFpEF Beta blockers - Heart Failure, Heart Failure, Diastolic | Phase 4 | Completed | Weill Medical College of Cornell University | 9 | 2021-04-01 | 2023-09-08 |
| Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF Beta blockers - Heart Failure, Heart Failure, Diastolic | Phase 4 | Completed | Weill Medical College of Cornell University | 9 | 2021-04-01 | 2024-04-09 |
| ACEI or ARB and COVID-19 Severity and Mortality in US Veterans ACEI/ARB, Non-ACEI/ARB, ACEI - Hypertension, COVID | Completed | University of Utah | 22213 | 2020-01-19 | 2021-04-28 | |
| Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate Propranolol, Pindolol, Dantrolene - Healthy Volunteers | Phase 2 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 47 | 2014-02-07 | 2024-10-16 |
| Evaluation of [11C]Cimbi-36 as an Agonist PET Radioligand for Imaging of 5-HT2A Receptors Citalopram and Pindolol, Placebo, Acute tryptophan depletion - Healthy | Not applicable | Completed | Gitte Moos Knudsen | 24 | 2013-01-01 | 2025-02-20 |
| Comparison of the Pharmacokinetics of Three Generic Medications and Their Respective Brand Preparations Trazodone, Quetiapine, Pindolol - Healthy | Phase 1 | Unknown | University of Ottawa | 30 | 2011-07-01 | 2011-07-22 |
| EScitalopram PIndolol ONset of Action escitalopram, pindolol, escitalopram - Unipolar Depression | Phase 2 / Phase 3 | Terminated | Markus KOSEL | 18 | 2010-10-01 | 2015-05-27 |
| Effects of Intensive Long-Term Vasodilation in Hypertensive Patients With Microvascular Angina Pectoris Lercanidipine, Valsartan, Nicorandil - Microvascular Angina, Hypertension | Not applicable | Terminated | University of Aarhus | 10 | 2007-01-01 | 2009-05-06 |
| Can Additional Drug Therapy Accelerate Response Time to Antidepressants citalopram + tiodothyronine, or + pindolol, or + placebo - Depression | Phase 4 | Withdrawn | Mark Frye | 2004-01-01 | 2015-06-01 | |
| Citalopram Versus Citalopram Plus Pindolol in Major Depressive Disorder Pindolol - Major Depressive Disorder, Antidepressant Treatment Response | Phase 2 | Completed | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 30 | 2002-12-01 | 2009-07-02 |
| Trial of Pindolol Augmentation in Venlafaxine Treated Patients With Major Depression Pindolol and venlafaxin - Major Depression | Not applicable | Terminated | Hillerod Hospital, Denmark | 31 | 2002-08-01 | 2007-12-27 |
| Pharmacological Interaction Between Pindolol and MDMA (3,4-Methylenedioxymethamphetamine) MDMA, Pindolol - Mood Disorder, Substance-Related Disorders | Phase 1 | Completed | University Hospital, Basel, Switzerland | 16 | 2001-06-01 | 2009-06-15 |
Depressive Disorder, Major (2) · Heart Diseases (2) · Heart Failure (2) · Heart Failure, Diastolic (2) · Hypertension (2) · Amphetamine-Related Disorders (1) · Barakat syndrome (1) · Cachexia (1) · Depression (1) · Depressive Disorder (1) · Microvascular Angina (1) · Mood Disorders (1) · Substance-Related Disorders (1)
Weill Medical College of Cornell University (2) · Actimed Therapeutics Ltd (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1) · Gitte Moos Knudsen (1) · Hillerod Hospital, Denmark (1) · Johns Hopkins University (1) · Mark Frye (1) · Markus KOSEL (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · University Hospital, Basel, Switzerland (1) · University of Aarhus (1) · University of Ottawa (1) · University of Utah (1)
United States (6) · Denmark (3) · Switzerland (2) · Canada (1) · Spain (1) · United Kingdom (1)
Parag Goyal, MD (2) · Adam P Bress, PharmD, MS (1) · Francesc Artigas, PhD (1) · Franck Chenu, PharmD, Phd (1) · Gitte M Knudsen, DMSc (1) · Kent L Christensen, MD, DrMSc (1) · Kong Y Chen, Ph.D. (1) · Mark A Frye, MD (1) · Markus Kosel, MD-PhD (1) · Matthias E Liechti, MD (1) · Per Bech, Professor (1) · Pierre Blier, MD, PhD (1)
PMID 21034693, PMID 22458638, PMID 29980535, PMID 33891615, PMID 39665235
K76AG064428 (1)