62 completed, 23 unknown, 14 terminated, 6 withdrawn. 34 Not applicable, 33 Phase 2, 26 Phase 1, 17 Phase 4, 11 Phase 3.
Follow Photodynamic therapy: new trials by email Literature Review of Photodynamic therapy trials Research Report on Photodynamic therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 2 Study of Methylene Blue Photodynamic Therapy for Treatment of Breast Abscesses Standard of care breast abscess drainage, Methylene Blue, Lipid Emulsion - Breast Abscess | Phase 2 | Not yet recruiting | University of Rochester | 50 | 2027-07-01 | 2026-08-19 |
| An Open-Label Pharmacokinetic Study for Patients With Actinic Keratosis on the Upper Extremities or the Face Investigational drug, Photodynamic therapy - Actinic Keratosis (AK) | Phase 1 | Recruiting | Sun Pharmaceutical Industries Limited | 48 | 2026-08-04 | 2026-08-13 |
| PDT vs Peels for Treatment of Actinic Keratoses Photodynamic Therapy, Chemical Peels - Actinic Keratoses | Phase 2 | Not yet recruiting | Northwestern University | 60 | 2026-08-01 | 2026-07-01 |
| Photodynamic Therapy and Post-Endodontic Pain in Undergraduate-Performed Treatments Photodynamic Therapy - Pulpitis | Completed | Atlas University | 95 | 2025-01-01 | 2025-11-28 | |
| Diode Laser as an Adjunct to Professional Mechanical Plaque Removal Professional mechanical plaque removal and Laser, Professional mechanical plaque removal - Periodontitis, Pocket, Periodontal | Not applicable | Active not recruiting | University of Sulaimani | 40 | 2025-01-01 | 2026-05-04 |
| Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer Biopsy, Biospecimen Collection, Computed Tomography - Locally Advanced Pancreatic Adenocarcinoma, Metastatic Pancreatic Adenocarcinoma | Phase 2 | Active not recruiting | Mayo Clinic | 24 | 2024-12-06 | 2026-06-18 |
| Hematoporphyrin Photodynamic Therapy for Esophageal Cancer photodynamic therapy - Esophageal Cancer, Photodynamic Therapy | Phase 4 | Enrolling by invitation | Sun Yat-sen University | 198 | 2024-09-18 | 2026-05-22 |
| Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer Aminolevulinic Acid, Biospecimen Collection, Computed Tomography - Locally Advanced Colorectal Carcinoma, Recurrent Colorectal Carcinoma | Phase 1 / Phase 2 | Recruiting | Roswell Park Cancer Institute | 21 | 2024-07-30 | 2026-10-15 |
| Comparing Photodisinfection of Chitosan NP Enriched ICG Over ICG as Adjunct to OFD: RCT PHOTODYNAMIC THERAPY - Periodontal Pocket | Not applicable | Unknown | Krishnadevaraya College of Dental Sciences & Hospital | 24 | 2024-07-01 | 2024-07-29 |
| The Effect of Photodynamic Therapy on Plaque in Orthodontic Patients Photodynamic therapy, Tricalcium phosphate (TCP) varnish with 5% NaF, Chlorhexidine varnish - Plaque, Dental, Dental Plaque Induced Gingivitis | Not applicable | Unknown | University of Zagreb | 50 | 2024-05-01 | 2024-03-26 |
| Photodynamic Therapy and Topical Antifungal for Onychomycosis in Patients With Diabetes. Photodynamic therapy - Dermatologic Disease, Onychomycosis of Toenail | Not applicable | Unknown | Universidad Complutense de Madrid | 10 | 2024-04-17 | 2024-07-03 |
| Efficacy of Photodynamic Therapy and LASER Disinfection in Periodontal Therapy for Treatment of Periodontitis LASER disinfection, Photodynamic therapy, Root surface debridement - Periodontitis | Not applicable | Unknown | University of Baghdad | 18 | 2024-03-01 | 2024-03-12 |
| Effect of Treatments on Pain and Quality of Life in Individual With Burning Mouth Syndrome topical placebo rinse, topical clonazepam rinse, oral alpha-lipoic acid capsule - Burning Mouth Syndrome | Phase 4 | Completed | Federal University of Minas Gerais | 50 | 2023-11-01 | 2026-08-17 |
| Effects of Adjunct Antimicrobial Photodynamic Therapy in Periodontal Treatment of Patients With Obesity antimicrobial photodynamic therapy (aPDT), Control - Periodontitis, Obesity | Not applicable | Recruiting | University of Sao Paulo | 24 | 2023-10-09 | 2026-05-04 |
| A Comparison of Photodynamic Therapy and Topical Clobetasol in Treatment of Oral Lichen Planus: a Split-Mouth Randomised Controlled Study Photodynamic Therapy, Clobetasol - Oral Lichen Planus | Phase 2 | Completed | Wroclaw Medical University | 29 | 2023-06-01 | 2024-12-30 |
| Effect of Photodynamic Therapy on Skin Microbiome. Single Center Study (PHOMIC-III) Photodynamic Therapy - Prosthesis and Implants, Surgical Site Infection | Early Phase 1 | Unknown | University of Zurich | 20 | 2023-02-04 | 2023-05-25 |
| Photodynamic Therapy With Hydrogel Dressing for Chronic Wounds Photodynamic therapy, Hydrogel dressing - Photodynamic Therapy | Not applicable | Unknown | Army Medical University, China | 69 | 2023-01-01 | 2024-07-30 |
| Pembrolizumab and Photodynamic Therapy in Previously Treated Metastatic Esophageal Squamous Cell Carcinoma Pembrolizumab, Sinoporphyrin Sodium, Photodynamic therapy - Esophageal Squamous Cell Carcinoma | Phase 2 | Not yet recruiting | Peking University | 54 | 2022-12-01 | 2022-11-28 |
| Clinical and Radiographic Evaluation of Photodynamic Therapy for Root Canal Treatment of Primary Molars photodynamic therapy, pulpectomy with metapex - Photodynamic Therapy | Not applicable | Unknown | Mansoura University | 60 | 2022-12-01 | 2023-04-20 |
| Photodynamic Therapy to Amplify the Response to Immunotherapy in Patients With Non-small Cell Lung Cancer With Pleural Disease Porfimer Sodium, Video-Assisted Thoracic Surgery, Photodynamic Therapy - Lung Non-Small Cell Carcinoma, Pleural Disorder | Phase 1 | Terminated | Roswell Park Cancer Institute | 5 | 2022-03-10 | 2026-02-04 |
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Keratosis, Actinic (10) · Chronic Periodontitis (8) · Carcinoma, Non-Small-Cell Lung (6) · Carcinoma, Basal Cell (5) · Cholangiocarcinoma (5) · Squamous Cell Carcinoma of Head and Neck (5) · Macular Degeneration (4) · Periodontitis (4) · Acne Vulgaris (3) · Bile Duct Neoplasms (3) · Colorectal Neoplasms (3) · Halitosis (3) · Leukoplakia, Oral (3) · Lichen Planus, Oral (3) · Liver Neoplasms (3)
Roswell Park Cancer Institute (10) · University of Sao Paulo (7) · Mayo Clinic (5) · University of Nove de Julho (4) · Bispebjerg Hospital (3) · National Cancer Institute (NCI) (3) · Shahid Beheshti University of Medical Sciences (3) · Sun Yat-sen University (3) · Wroclaw Medical University (3) · Asan Medical Center (2) · King Saud University (2) · Light Sciences LLC (2) · Northwestern University (2) · QLT Inc. (2) · University of Zurich (2)
United States (41) · Brazil (12) · China (12) · Canada (4) · Denmark (4) · Germany (4) · Poland (4) · Saudi Arabia (3) · South Korea (3) · Iraq (2) · Switzerland (2) · Taiwan (2) · Austria (1) · Chile (1) · Croatia (1)
Hassan Arshad (2) · Murad Alam, MD (2) · Zohreh Tehranchi-nia, assist.prof. (2) · Aaron Mangold (1) · Alexandra Geusau, Prof. Dr. (1) · Allen Ho, MD (1) · Amr Ahmed (1) · Andrew Strong, Ph.D (1) · Annette Verzijl, MD (1) · Anthony S Dakwar (1) · Ariel Hasson, MD (1) · Axel Hauschild, Professor MD (1)
PMID 20510306, PMID 23055220, PMID 23868427, PMID 24485665, PMID 25555191, PMID 25808980, PMID 27330702, PMID 28498507, PMID 28793884, PMID 30222972, PMID 30392080, PMID 31027098, PMID 31277154, PMID 32727733, PMID 33647286, PMID 33987732, PMID 34087466, PMID 34261044, PMID 35367616, PMID 36727801, PMID 39838651, PMID 40522203, PMID 41091662, PMID 41375569, PMID 42625164
P01CA084203 (2), P30CA016056 (2), 2018 (1), 5UH3CA189901-04 (1), P30CA060553 (1), R01CA111603 (1), R21CA153594 (1), U01CA099168 (1), UL1TR001412 (1)