16 completed, 3 unknown, 2 terminated, 1 withdrawn. 7 Phase 4, 5 Phase 3, 3 Not applicable, 2 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 7 | Completed 6, Withdrawn 1 |
| Phase 3 | 5 | Completed 3, Terminated 1, Unknown 1 |
| Not applicable | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 2 | Unknown 2 |
Follow Perphenazine: new trials by email Literature Review of Perphenazine trials Research Report on Perphenazine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data Neuraxial Analgesia, Regional Block 1: Paravertebral, Perphenazine - Perioperative Optimization | Phase 3 | Completed | Jennifer Holder-Murray | 3395 | 2023-05-15 | 2026-05-28 |
| Networked Drug REpurposing for Mechanism-based neuroPrOtection in Acute Ischaemic STROKE Riociguat, Propylthiouracil, Perphenazine - Ischemic Stroke, Acute | Phase 2 | Unknown | Maastricht University | 28 | 2022-09-05 | 2023-10-19 |
| Possible Effects of Propylthiouracil, Riociguat and Perphenazine on Circulation of Healthy Volunteers Propylthiouracil, Riociguat, Perphenazine - Drug Drug Interaction, Safety Issues | Phase 1 | Completed | Maastricht University | 8 | 2021-03-18 | 2022-04-04 |
| Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies Lithium Carbonate, Lamotrigine, Valproic Acid - Bipolar Disorder | Terminated | University of New Mexico | 1037352 | 2016-09-01 | 2024-03-12 | |
| Family Intervention in Recent Onset Schizophrenia Treatment (FIRST) Caregiver psycho-education and skills training, Caregiver support available at the study site, Paliperidone palmitate - Schizophrenia | Completed | Janssen Scientific Affairs, LLC | 296 | 2015-07-24 | 2019-01-23 | |
| A Study to Compare Disease Progression and Modification Following Treatment With Paliperidone Palmitate Long-Acting Injection or Oral Antipsychotics in Participant's With Recent-onset Schizophrenia or Schizophreniform Aripiprazole, Haloperidol, Olanzapine - Schizophrenia, Psychotic Disorders | Phase 3 | Completed | Janssen Scientific Affairs, LLC | 337 | 2015-07-08 | 2025-04-29 |
| Evaluation of the Necessity of Long-term Pharmacological Treatment With Antipsychotics in Schizophrenic Patients Olanzapine, Amisulpride, Risperidone - Schizophrenia, Schizophrenia and Disorders With Psychotic Features | Phase 4 | Completed | Technical University of Munich | 21 | 2015-02-01 | 2018-10-11 |
| Pharmacovigilance in Gerontopsychiatric Patients Phenobarbital, Phenytoin, Carbamazepine - Dementia, Depression | Phase 3 | Terminated | Hannover Medical School | 407 | 2015-01-01 | 2018-02-28 |
| Lurasidone Effects on Tissue Glutamate in Schizophrenia Lurasidone, Haloperidol, Perphenazine - Schizophrenia, Schizoaffective Disorder | Phase 4 | Completed | University of Texas Southwestern Medical Center | 35 | 2013-02-01 | 2021-03-01 |
| Clinical Trial to Evaluate the Efficacy of Treatment vs Discontinuation in a First Episode of Non-affective Psychosis Discontinuation antipsychotic treatment, Antipsychotic treatment - Psychosis Nos/Other | Phase 3 | Unknown | Fundación Pública Andaluza Progreso y Salud | 104 | 2012-11-01 | 2014-12-05 |
| A Randomized Double-blind Trial With 6 Antipsychotic Drugs for Schizophrenia Typical antipsychotic, Risperidone, Olanzapine - Schizophrenia | Not applicable | Completed | Beijing HuiLongGuan Hospital | 550 | 2012-06-01 | 2016-07-12 |
| Antipsychotics and Risk of Hyperglycemic Emergencies Olanzapine, Risperidone, atypical antipsychotics (other) - Psychotic Disorders, Schizophrenia | Completed | Canadian Network for Observational Drug Effect Studies, CNODES | 725489 | 2012-04-01 | 2015-10-21 | |
| Correlation Between Cognitive Function and Relapse of Schizophrenia Regarding Dose Reduction reduction of risperidone, haloperidol, olanzapine, quetiapine, aripiprazole, paliperidone, levomepromazine, perphenazine - Schizophrenia Relapse | Not applicable | Completed | Juntendo University | 139 | 2011-04-01 | 2021-09-09 |
| Twelve Month Study Comparing Paliperidone Palmitate and Select Oral Antipsychotics in Adults With Schizophrenia Who Have Been Recently Discharged From an Inpatient Psychiatric Hospital paliperidone palmitate, risperidone, olanzapine - Schizophrenia | Phase 4 | Withdrawn | Ortho-McNeil Janssen Scientific Affairs, LLC | 2010-08-01 | 2013-07-08 | |
| 15 Month Study for Adults Who Have Been Diagnosed With Schizophrenia and Incarcerated paliperidone, risperidone, haloperidole - Schizophrenia | Phase 4 | Completed | Janssen Scientific Affairs, LLC | 450 | 2010-05-01 | 2015-04-24 |
| Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics Aripiprazole or Perphenazine, Metformin, Olanzapine, quetiapine, risperidone, ziprasidone, aripiprazole, asenapine, iloperidone, lurasidone, paliperidone, or olanzapine/fluoxetine - Psychotic Disorders | Phase 4 | Completed | Johns Hopkins University | 127 | 2009-01-01 | 2017-04-25 |
| Comparison of Optimal Antipsychotic Treatments for Adults With Schizophrenia Olanzapine, Perphenazine, Aripiprazole - Schizophrenia | Phase 4 | Completed | National Institute of Mental Health (NIMH) | 21 | 2008-12-01 | 2013-02-08 |
| A Double-Blind, Controlled Study of Aripiprazole in Co-Morbid Schizophrenia and Cocaine Dependence Aripiprazole, Perphenazine - Schizophrenia, Cocaine Dependence | Phase 2 | Unknown | Paul Saenger | 44 | 2008-08-01 | 2012-09-07 |
| A Positron Emission Tomography (PET) Study to Assess the Degree of Dopamine-2 (D2) Receptor Occupancy in the Human Brain After Single Doses of BL-1020 or Perphenazine in Healthy Male Subjects Using [11C]Raclopride as PET Tracer BL 1020, Perphenazine - Healthy | Phase 1 | Completed | BioLineRx, Ltd. | 2007-05-01 | 2009-07-21 | |
| Antipsychotic Polypharmacy in Schizophrenia 2 antipsychotic medications (combinations of olanzapine, risperidone, clozapine, seroquel, haldol, perphenazine), main antipsychotic medication and placebo - Schizophrenia | Not applicable | Completed | Centre for Addiction and Mental Health | 100 | 2006-11-01 | 2009-05-19 |
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Schizophrenia (13) · Psychotic Disorders (6) · Bipolar Disorder (2) · Dementia (2) · Alzheimer Disease (1) · Anxiety Disorders (1) · Cocaine-Related Disorders (1) · Dementia, Vascular (1) · Depression (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Drug-Related Side Effects and Adverse Reactions (1) · Ischemic Stroke (1) · Obesity (1) · Postoperative Nausea and Vomiting (1)
Janssen Scientific Affairs, LLC (3) · Maastricht University (2) · National Institute of Mental Health (NIMH) (2) · Beijing HuiLongGuan Hospital (1) · BioLineRx, Ltd. (1) · Bruce Pollock (1) · Canadian Network for Observational Drug Effect Studies, CNODES (1) · Centre for Addiction and Mental Health (1) · Fundación Pública Andaluza Progreso y Salud (1) · Hannover Medical School (1) · Jennifer Holder-Murray (1) · Johns Hopkins University (1) · Juntendo University (1) · Ortho-McNeil Janssen Scientific Affairs, LLC (1) · Paul Saenger (1)
United States (11) · Germany (4) · Canada (2) · Brazil (1) · China (1) · Mexico (1) · Puerto Rico (1) · Spain (1) · Sweden (1)
Bruce G. Pollock, M.D., Ph.D. (1) · Carol A Tamminga, M.D. (1) · Christoph Correll, MD (1) · Christophe G Lambert, PhD (1) · David Mamo, MD, MSc (1) · Gloria Reeves, MD (1) · Helge Frieling, Prof., MD (1) · Jeffrey A Lieberman, MD (1) · Joseph P. McEvoy, MD (1) · Linmarie Sikich, MD (1) · Lorraine Lipscombe, MD, MSc (1) · Mark A. Riddle, MD (1) · Markus Dold, MD (1)
PMID 37756123, PMID 16172203, PMID 16585434, PMID 16585435, PMID 17151158, PMID 17151159, PMID 19640511, PMID 20816031, PMID 20868641, PMID 22000938, PMID 22290266, PMID 22316567, PMID 23235268, PMID 23727135, PMID 24028745, PMID 24030617, PMID 24183751, PMID 24400912, PMID 24524169, PMID 24569099, PMID 24581419, PMID 24581550, PMID 24630140, PMID 24726579, PMID 24850369, PMID 24862257, PMID 25075930, PMID 25375367, PMID 25562591, PMID 25567425, PMID 25668654, PMID 25679125, PMID 25938474, PMID 26403322, PMID 26479222, PMID 26581028, PMID 26742509, PMID 26845273, PMID 27180047, PMID 28441618, PMID 28693755, PMID 28901625, PMID 29069114, PMID 29920885, PMID 30172739, PMID 30986735, PMID 31237566, PMID 31651956, PMID 31744781, PMID 32220153
N01MH090001 (2), N01MH90001 (2), 2019 (1), R01MH059666 (1), R01MH080270 (1)