32 completed, 10 unknown, 5 recruiting, 4 withdrawn. 17 Phase 4, 16 Not applicable, 8 Phase 3, 7 Phase 2, 3 Early Phase 1.
Follow NSAID: new trials by email Literature Review of NSAID trials Research Report on NSAID
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison Of Acetaminophen, NSAIDs, And Trypsin-Chymotrypsin Plus Acetaminophen For Post-Endodontic Pain After Single-Visit Root Canal Treatment Acetaminophen, NSAID, trypsin-chymotrypsin - Symptomatic Irreversible Pulpitis (SIP) | Early Phase 1 | Recruiting | Dow University of Health Sciences | 90 | 2026-08-02 | 2026-08-19 |
| Colchicine for Autoimmune and Subacute Thyroiditis colchicine, Prednisolone, NSAID - Hashimoto Thyroiditis, Subacute Thyroiditis | Phase 2 / Phase 3 | Recruiting | Mansoura University | 300 | 2026-06-15 | 2026-07-29 |
| The Effect of Colchicine on the Occurrence of Atrial Fibrillation After Cardiac Surgery NSAID, Colchicine 0.5 MG - Coronary Artery Disease, Atrial Fibrillation | Phase 4 | Completed | Tomsk Cardiology Research Institute | 140 | 2025-01-20 | 2026-09-30 |
| Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial NSAID, Opioid, Acetaminophen - Surgery, Pain, Post Operative | Phase 4 | Recruiting | University of Michigan | 900 | 2025-01-10 | 2026-10-20 |
| Comparison Paravertebral and Serratus Anterior Plane Block in Video-assisted Thoracoscopic Surgery. Bupivacaine, Morphine, Paracetamol - Lung Cancer (NSCLC), Lung Adenocarcinoma | Not applicable | Active not recruiting | Hacettepe University | 122 | 2024-12-01 | 2025-06-04 |
| Pain Relief After Corneal Collagen Cross-Linking Gabapentin, Targin, NSAID - Provide Evidence-based Recommendations for Clinicians to Optimize Pain Control After CXL | Early Phase 1 | Unknown | Assaf-Harofeh Medical Center | 51 | 2024-02-01 | 2024-01-19 |
| L-Arginine Role for Stone Lower Ureter : A Randomized Control Study NSAID, L-Arginine, 500 Mg Oral Capsule, Tamsulosin 0.4 mg QD - Stone Lower Ureter | Phase 4 | Completed | Sohag University | 153 | 2023-07-01 | 2024-12-31 |
| Effect of Weight Reduction and Aerobic Exercise on PMS Symptoms in Obese Females Medical treatment., weight reduction, exercise - Premenstrual Syndrome | Not applicable | Completed | Cairo University | 40 | 2023-05-01 | 2024-06-11 |
| Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial NSAID, Opioid, Acetaminophen - Surgery, Pain, Postoperative | Phase 4 | Recruiting | University of Michigan | 900 | 2023-02-06 | 2026-08-28 |
| Efficacy of Duloxetine Compared to NSIADs in Osteoarthritis of Knee Duloxetine 30 MG, Nonsteroidal Antiinflammatory Drug - Osteo Arthritis Knee | Phase 2 | Completed | Hawler Medical University | 200 | 2022-08-20 | 2023-03-14 |
| 3D Evaluation of Postoperative Edema After Third Molar Surgery Combination of corticosteroid (methylprednisolone - Medrol, 16mg Pfizer Laboratories) therapy and non-steroidal anti-inflammatory (Ibuprofen 600mg Mylan) therapy, Non-steroidal anti-inflammatory therapy (Ibuprofen 600mg Mylan) - Molar, Third, Third Molar Surgery | Phase 4 | Unknown | Implantology Institute | 40 | 2022-07-01 | 2023-07-12 |
| A Randomized Trial of NSAID Dosing Strategies NSAID - Musculoskeletal Pain, Acute Pain | Phase 4 | Completed | Montefiore Medical Center | 407 | 2022-06-01 | 2023-08-15 |
| Paracetamol Compared With Ketorolac for Post-operative Analgetic Paracetamol, Ketorolac - Pain, Postoperative | Phase 4 | Completed | Universitas Indonesia | 85 | 2022-03-31 | 2022-09-06 |
| The Clinical Efficacy and the Changes of Immune Cells Subsets With Bioagents in Ankylosing Spondylitis Patients Secukinumab 150 mg/ml, Adalimumab Ab, NSAID - Ankylosing Spondylitis | Phase 4 | Unknown | Qilu Hospital of Shandong University | 100 | 2022-03-15 | 2023-11-18 |
| Evaluation of Erector Spina Plane Block(ESPB)'s Effectiveness on Patients With Lumbar Radiculopathy Erector Spinae Plane Block, NSAID, Home Exercise Programme - Radiculopathy, Radiculopathy Lumbar | Early Phase 1 | Withdrawn | Bezmialem Vakif University | 2022-03-01 | 2025-02-07 | |
| The Effect of PCA on PONV After Microvascular Decompression NSAID, Opioid - Postoperative Nausea and Vomiting | Not applicable | Unknown | Seoul National University Hospital | 94 | 2021-12-20 | 2023-04-13 |
| The Effect of Physiotherapy on Chronic Low Back Pain Nsaid, Phsiotheraphy - Chronic Low-back Pain | Not applicable | Completed | Kayseri City Hospital | 60 | 2020-11-26 | 2024-02-13 |
| Pain Management After Transnasal Transsphenoidal Surgery for Pituitary Adenomas NSAID, Tramadol - Pituitary Adenoma, Surgery | Not applicable | Unknown | Peking Union Medical College Hospital | 202 | 2020-10-31 | 2020-11-03 |
| Endovascular Versus Medical Treatment for the Pelvic Congestion Syndrome Medtronic® Concerto® detachable coil system, sclerosis, Diosmin / Hesperidin - Pelvic Congestive Syndrome, Pelvic Varices | Phase 4 | Unknown | Hospital de Clínicas Dr. Manuel Quintela | 120 | 2020-10-01 | 2020-04-24 |
| Anesthesia and Immunological and Oxidative Stress in Relation to Abdominal Cancer Surgery Colon Resection, Epidural anesthesia, NSAID - Anesthesia, Colon Cancer | Withdrawn | University of Copenhagen | 2020-06-04 | 2020-11-05 |
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Pain, Postoperative (6) · Acute Pain (4) · Low Back Pain (3) · Osteoarthritis (3) · Wounds and Injuries (3) · Agnosia (2) · Arthritis (2) · Chronic Pain (2) · Colonic Neoplasms (2) · Ductus Arteriosus, Patent (2) · Hypertension (2) · Osteoarthritis, Knee (2) · Pain (2) · Rib Fractures (2) · Adenocarcinoma of Lung (1)
Pfizer (2) · Sahlgrenska University Hospital (2) · Seoul National University Hospital (2) · University of Michigan (2) · Aalborg University (1) · Assaf-Harofeh Medical Center (1) · Bezmialem Vakif University (1) · Biogen (1) · Bispebjerg Hospital (1) · Boehringer Ingelheim (1) · Brooklyn ImmunoTherapeutics, LLC (1) · Cairo University (1) · Dow University of Health Sciences (1) · Emory University (1) · First Affiliated Hospital Xi'an Jiaotong University (1)
United States (15) · Turkey (Türkiye) (6) · Denmark (5) · South Korea (5) · Canada (4) · China (3) · Egypt (3) · Russia (3) · Sweden (3) · Brazil (2) · Colombia (2) · India (2) · Israel (2) · Mexico (2) · Philippines (2)
Eva-Corina Caragounis, MD (2) · Hans Granhed, MD PhD (2) · Mark Bicket, MD, PhD (2) · Abigail L Mackey, PhD (1) · Amr A. El Sehrawy, MD, PhD, FRCPE (1) · Bartosz Dalewski, DMD,PhD (1) · Benjamin W Friedman, MD (1) · Bernie E Medise, Dr (1) · Bing Xing, MD (1) · Catarina Pinto, DDS (1) · Cathy Hammerman, MD (1) · Chang-Hoon Koo (1) · Chun Kee Chung, Professor (1)
PMID 18622068, PMID 21029429, PMID 24625625, PMID 26554876, PMID 30340932, PMID 30850756, PMID 30936738, PMID 31255386, PMID 32738599, PMID 33538113, PMID 35217440, PMID 35232805, PMID 35351194, PMID 35960482, PMID 35980115, PMID 36301512, PMID 36474952, PMID 37470295, PMID 37652258, PMID 38335521, PMID 38343426, PMID 38381930, PMID 38650049, PMID 40187774, PMID 40375321, PMID 40868251, PMID 41020650, PMID 42208996, PMID 42386760
2008 (1)