17 completed, 6 unknown, 4 recruiting, 2 terminated. 10 Not applicable, 8 Phase 3, 8 Phase 4, 3 Phase 1, 2 Phase 2.
Follow Noradrenaline: new trials by email Literature Review of Noradrenaline trials Research Report on Noradrenaline
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Co-Administration of Crystalloid Fluid and Norepinephrine for Preventing Acute Kidney Injury in Septic Shock Norepinephrine, Crystalloid Fluid Resuscitation - Septic Shock, Acute Kidney Injury | Not applicable | Not yet recruiting | Universitas Sumatera Utara | 100 | 2026-04-23 | 2026-02-18 |
| Preventing Cardiovascular Collapse With Vasopressors During Tracheal Intubation Noradrenaline - Critical Illness, Respiratory Failure | Phase 3 | Recruiting | University of Turin, Italy | 420 | 2024-08-01 | 2025-03-28 |
| Inotropic Effects of Vasopressin Versus Noradrenaline In Patients With Vasoplegic Syndrome After Cardiac Surgery Vasopressin intravenous infusion, Norepinephrine intravenous infusion - Vasoplegic Syndrome of Cardiac Surgery | Phase 4 | Recruiting | University of Sao Paulo | 350 | 2024-04-01 | 2025-04-30 |
| Vasopressor Impact on Brain Circulation, Organ Blood Flow and Tissue Oxygenation During Anesthesia Noradrenalin, Phenylephrine - Hypotension | Phase 2 / Phase 3 | Recruiting | University of Aarhus | 32 | 2023-12-20 | 2026-03-19 |
| Early Initiated Vasopressor Therapy in the Emergency Department Noradrenaline - Shock, Shock, Septic | Phase 3 | Recruiting | Odense University Hospital | 320 | 2023-12-08 | 2025-07-01 |
| Hypotension Prediction Index vs Norepinephrine Infusion for Prevention of Spinal Hypotension for Cesarean Delivery Hypotension Prediction Index, Norepinephrine - Hypotension During Surgery, Hypotension Drug-Induced | Phase 4 | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 150 | 2023-09-01 | 2023-08-03 |
| Prophylactic Perioperative Infusion of Ephedrine Versus Noradrenaline in Patients Undergoing Cesarean Delivery Under Spinal Anesthesia Ephedrine, Noradrenaline - Perioperative Infusion, Ephedrine | Not applicable | Completed | Tanta University | 100 | 2023-07-01 | 2025-07-16 |
| Noradrenaline Versus Glypressin for Prevention of Hypotension After Deflation of Tourniquet in Knee Arthroplasty Saline, Norepinephrine, glypressin - Norepinephrine, Glypressin, Tourniquet Deflation, Hypotension | Not applicable | Completed | Tanta University | 135 | 2022-12-01 | 2023-11-22 |
| HPI Algorithm for the Prevention of IOH During Spinal Surgery [HPIFPIOH] HPI algorithm using Edwards device https://www.edwards.com/gb/devices/decision-software/hpi, Vasoactive Agent - Intraoperative Hypotension | Not applicable | Completed | Attikon Hospital | 85 | 2022-05-11 | 2025-03-19 |
| Therapeutic Study Evaluating the Efficacy of Noradrenaline in the Prevention of Hypotension Related to Intubation for Cardiac or Thoracic Surgery noradrenaline - Cardiac Disorder, Hypotension | Phase 3 | Completed | Nantes University Hospital | 211 | 2022-04-27 | 2024-03-07 |
| Comparison of Hemodynamic Results of Two Different Fluid Managements isotonic solution, Noradrenaline - Perioperative Fluid Management | Not applicable | Unknown | Istanbul University | 40 | 2022-04-01 | 2023-10-23 |
| The Impact of Early Norepinephrine Administration on Outcomes of Patients With Sepsis-induced Hypotension Crystalloid, noradrenaline - Norepinephrine, Sepsis | Not applicable | Completed | Tanta University | 64 | 2021-05-01 | 2023-03-24 |
| Norepinephrine for Hypotension in Cesarean Section Norepinephrine, Phenylephrine - Hypotension, Cesarean Section | Not applicable | Completed | Assiut University | 180 | 2021-04-10 | 2023-01-04 |
| The Influence of Noradrenaline on Coagulation and Fibrinolysis in Severe Isolated Brain Injury noradrenaline - Brain Injuries, Traumatic, Coagulopathy | Unknown | University Medical Centre Ljubljana | 60 | 2020-09-01 | 2020-08-17 | |
| The Effect of Norepinephrine on Cardiac Output in Patients Undergoing Liver Transplant . Noradrenaline - Liver Transplantation | Not applicable | Completed | Cairo University | 31 | 2019-12-15 | 2021-11-09 |
| Norepinephrine and Phenylephrine, Which Better for Elderly? norepinephrine, Phenylephrine - Hypotension | Phase 3 | Unknown | The Second Affiliated Hospital of Dalian Medical University | 100 | 2019-10-06 | 2019-10-08 |
| Acute Renal Injury After Major Elective Non-Cardiac Surgery Crystalloid Solutions, Colloid Blood Volume Expanders, blood replacement - Acute Renal Injury | Completed | Istanbul University | 425 | 2019-06-01 | 2021-09-22 | |
| Angiotensin II for Septic Shock Treatment Angiotensin II, Normal saline, Norepinephrine - Septic Shock | Phase 3 | Suspended | Cairo University | 20 | 2019-04-01 | 2019-01-16 |
| Comparison of Two Doses of Norepinephrine in Preventing Hypotension After Spinal Anesthesia Norepinephrine: 1mcg/kg, Norepinephrine 0,5mcg/kg - Anesthesia, Adverse Effect | Phase 4 | Completed | University Tunis El Manar | 124 | 2018-05-03 | 2025-06-12 |
| Vasopressor Infusion in Cesarean Delivery Phenylephrine, Norepinephrine, Bupivacaine - Cesarean Section Complications, Spinal Anesthesia | Phase 4 | Unknown | Cairo University | 120 | 2017-08-20 | 2021-09-27 |
Showing 20 of 32. Sign in to see all of them.
Hypotension (10) · Shock, Septic (4) · Radiodermatitis (3) · Sepsis (3) · Acute Kidney Injury (2) · Postoperative Complications (2) · Alopecia (1) · Brain Injuries, Traumatic (1) · Cardiovascular Diseases (1) · Critical Illness (1) · Diabetes Insipidus (1) · Emergencies (1) · Endotoxemia (1) · Head and Neck Neoplasms (1) · Heart Diseases (1)
Cairo University (3) · ProCertus BioPharm, Inc (3) · Tanta University (3) · Institute of Liver and Biliary Sciences, India (2) · Istanbul University (2) · The Second Affiliated Hospital of Dalian Medical University (2) · Assiut University (1) · Attikon Hospital (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Federal University of São Paulo (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Nantes University Hospital (1) · Odense University Hospital (1) · Onze Lieve Vrouwe Gasthuis (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1)
Egypt (7) · France (3) · India (3) · United States (3) · Brazil (2) · Denmark (2) · Netherlands (2) · Turkey (Türkiye) (2) · China (1) · Greece (1) · Ireland (1) · Italy (1) · Sweden (1) · Tunisia (1) · United Kingdom (1)
Ahmed Mukhtar, Professor (2) · Ahmed M Mukhtar, MD (1) · Bethany M Anderson, MD (1) · Eleanor Harris, MD (1) · Flavia Machado, PhD (1) · Gaetano A Draisci, Prof (1) · Irfan Julio Nasution, MD (1) · James F Cleary, MBBS (1) · John G Laffey, MD (1) · Joseph Cheriyan, MBCHB, MA, FRCP (1)
PMID 15028145, PMID 16010055, PMID 16174954, PMID 16545046, PMID 17560680, PMID 18212647, PMID 18564410, PMID 21772125, PMID 22307074, PMID 22906292, PMID 23601499, PMID 25032942, PMID 26181335, PMID 27633962, PMID 28228155, PMID 28973220, PMID 29273054, PMID 30318393, PMID 31008870, PMID 31094744, PMID 31529354, PMID 31585796, PMID 31672462, PMID 33483132, PMID 33755076, PMID 40132839, PMID 40410627, PMID 41381314
2023 (1)