21 completed, 6 unknown, 3 not yet recruiting, 3 withdrawn. 34 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 34 | Completed 21, Unknown 6, Not yet recruiting 3, Withdrawn 3, Enrolling by invitation 1 |
Follow Naproxen: new trials by email Literature Review of Naproxen trials Research Report on Naproxen
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Human Experimental Models of Pain (HEMP) Placebo, Naproxen, Pregabalin - Acute Pain | Not applicable | Not yet recruiting | National Center for Complementary and Integrative Health (NCCIH) | 25 | 2026-11-04 | 2026-10-30 |
| Effectiveness of Opioid vs Pregabalin Plus Naproxen Sodium in Pain Management of Oral Cancer Patients Tramadol, Pregabalin + Naproxen Sodium - Oral Cancer, Oral Cavity Cancer | Not applicable | Enrolling by invitation | Mayo Hospital Lahore | 98 | 2026-02-01 | 2026-05-26 |
| Multimodal Pain Management After Wide Awake Local Anesthesia No Tourniquet Orthopedic Hand Surgery: A Randomized Control Trial Oxycodone 5mg taken first, Acetaminophen, Naproxen Tablets, 500 mg - Pain Management | Not applicable | Not yet recruiting | University of Puerto Rico | 100 | 2025-05-01 | 2025-04-08 |
| Optimal Treatment of Acute Skeletal Muscle Injury Naproxen 500 Mg, Rehabilitation, Placebo - Muscle Strain, Multiple Sites, Inflammation | Not applicable | Not yet recruiting | Bispebjerg Hospital | 20 | 2024-02-15 | 2024-02-23 |
| Naproxen and Lidocaine Gel Combination for Rib Fracture A gel combination containing 10% naproxen and 5% lidocaine, Dexketoprofen trometamol 50 mg IV - Thorax; Fracture, Rib Fracture | Not applicable | Completed | Ankara City Hospital Bilkent | 110 | 2024-01-01 | 2026-07-20 |
| Eliminating Narcotic Prescriptions from Outpatient Minimally Invasive Gynecologic Surgery prescription for regular acetaminophen and naproxen, prescription for regular acetaminophen , naproxen and dilaudid - Pain, Postoperative, Opioid Use | Not applicable | Completed | McGill University Health Centre/Research Institute of the McGill University Health Centre | 110 | 2022-07-04 | 2024-10-24 |
| Effects of Nigella Sativa Oil on Pain Intensity and Physical Functions in Patients With Knee Osteoarthritis Nigella sativa oil, Naproxen and lidocaine gel, Massage - Knee Osteoarthritis | Not applicable | Completed | Sultan ÇEÇEN | 75 | 2021-02-15 | 2023-09-14 |
| Effectiveness of Paracervical Block in Endometrial Sampling Procedures for Pain Control Paracervical Block, 550 mg Naproxen Sodium 60 minutes before the procedure, The capped needle - Office-based Endometrial Sampling Procedures | Not applicable | Completed | Ege University | 120 | 2020-09-28 | 2021-11-19 |
| The Effect of Turmeric on New Onset Primary Dysmenorrhea Naproxen, Turmeric - Primary Dysmenorrhea | Not applicable | Completed | Batman Training and Research Hospital | 90 | 2019-11-15 | 2020-04-24 |
| Is Kinesio Taping Effective to the Radial Nerve in Patients With Lateral Epicondylitis? Kinesio Tape, oral naproxen - Lateral Epicondylitis | Not applicable | Completed | Ankara Education and Research Hospital | 80 | 2019-01-07 | 2019-09-20 |
| Different Does of Acupuncture on Premenstrual Syndrome Efficacy Analysis NSAIDs or oral contraceptives treatment, Low dose acupuncture, High dose acupuncture - Premenstrual Syndrome | Not applicable | Unknown | Taipei City Hospital | 105 | 2019-01-01 | 2020-03-05 |
| Post Implantation Syndrome and Administration on NSAIDs in Patients Undergoing EVAR for AAA Drugs, Generic (Naprosyn), Placebo Oral Tablet - Aneurysm Abdominal, Endovacular Repair | Not applicable | Unknown | University of Thessaly | 186 | 2018-08-01 | 2018-11-26 |
| Efficacy of Multimodal Analgesia Following Hip Arthroscopy Zopiclone, Gabapentin, Celebrex - Hip Pain Chronic | Not applicable | Completed | Western University, Canada | 100 | 2018-04-06 | 2021-10-15 |
| Treatment of Early Phase Achilles Tendinopathy - the Effect of NSAIDs Naproxen 500 Mg, Placebo Oral Tablet, Heavy resistance training - Tendon Injuries, Achilles Tendinopathy | Not applicable | Completed | Bispebjerg Hospital | 70 | 2018-01-15 | 2020-07-09 |
| Migraine Treatment in ED Relaxation Therapy, Topiramate, Standard of Care - Migraine | Not applicable | Withdrawn | NYU Langone Health | 2015-12-01 | 2018-08-24 | |
| Different Analgesics Prior to Intrauterine Device (IUD) Insertion: Is There Any Evidence? Lidocaine, oral misoprostol, naproxen - IUD Insertion Complication | Not applicable | Unknown | Al Hayat National Hospital | 200 | 2015-07-01 | 2016-06-22 |
| Comparison of Different Analgesia Drug Regimens for Pain Control During ESWL for Renal Stones Lidocaine gel,, Naproxen Sodium, Lidocaine gel and Naproxen Sodium - Renal Stone | Not applicable | Completed | Shifa International Hospital | 135 | 2015-07-01 | 2016-06-01 |
| Naproxen on Tooth Sensitivity Caused by In-office Bleaching Naproxen - Toothache, Tooth Bleaching | Not applicable | Completed | Universidade Federal de Sergipe | 50 | 2015-05-01 | 2016-10-26 |
| Naproxen for Pain Control With Intrauterine Device Insertion Naproxen sodium, Placebo tablet - Contraception | Not applicable | Completed | Planned Parenthood League of Massachusetts | 119 | 2015-04-01 | 2017-06-22 |
| Efficacy of Intrauterine Lidocaine and Naproxen for Pain Control With Intrauterine Device Insertion Naproxen, Lidocaine, placebo - Contraception, Pain | Not applicable | Completed | Walter Reed National Military Medical Center | 160 | 2014-06-01 | 2018-11-08 |
Showing 20 of 34. Sign in to see all of them.
Osteoarthritis (6) · Agnosia (4) · Osteoarthritis, Knee (4) · Pain (4) · Migraine Disorders (3) · Rib Fractures (3) · Inflammation (2) · Pain, Postoperative (2) · Toothache (2) · Wounds and Injuries (2) · Acute Pain (1) · Aortic Aneurysm, Abdominal (1) · Cardiomyopathy, Hypertrophic (1) · Cognitive Dysfunction (1) · Flail Chest (1)
Primus Pharmaceuticals (4) · Bispebjerg Hospital (2) · Sahlgrenska University Hospital (2) · Al Hayat National Hospital (1) · Analgesic Solutions (1) · Ankara City Hospital Bilkent (1) · Ankara Education and Research Hospital (1) · Batman Training and Research Hospital (1) · Dent Neurologic Institute (1) · Ege University (1) · Kantonsspital Graubünden (1) · Mayo Hospital Lahore (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · NYU Langone Health (1) · National Center for Complementary and Integrative Health (NCCIH) (1)
United States (11) · Turkey (Türkiye) (5) · Canada (2) · Denmark (2) · Sweden (2) · Brazil (1) · Egypt (1) · Greece (1) · Pakistan (1) · Puerto Rico (1) · Saudi Arabia (1) · Switzerland (1) · Taiwan (1)
Eva-Corina Caragounis, MD (2) · Hans Granhed, MD PhD (2) · Joy Schechtman, DO (2) · Alan J Kivitz, MD (1) · Alan Kivitz, MD (1) · Andrew Zakhari, M.D. (1) · Brian Clausen, PT, M.Sc. (1) · Christian A. Foy, MD (1) · David A. McLain, MD (1) · David S Silver, MD (1) · Ewa M. Roos, Professor (1) · James Aisenberg, MD (1) · Keith R Edwards, M.D. (1) · Laszlo L Mechtler, MD (1)
PMID 19555810, PMID 20643821, PMID 21248083, PMID 23406052, PMID 25399048, PMID 25579873, PMID 26926930, PMID 27824753, PMID 27836677, PMID 29107059, PMID 31516731, PMID 33719579, PMID 40375321, PMID 41491106