6 completed, 1 active not recruiting, 1 terminated. 8 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Completed 6, Active not recruiting 1, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow L-Arginine: new trials by email Literature Review of L-Arginine trials Research Report on L-Arginine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent Claudication Tetrahydrobiopterin 10 mg/kg, Tetrahydrobiopterin 20 mg/kg, L-Ascorbate - Claudication, Intermittent, Peripheral Artery Disease | Phase 1 | Active not recruiting | Louis Messina | 10 | 2021-06-15 | 2026-04-15 |
| The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction BQ-788, BQ-123, L-Arginine - Cardiovascular Diseases, Cardiovascular Risk Factor | Phase 1 | Completed | The University of Texas at Arlington | 19 | 2018-10-01 | 2024-06-11 |
| Safety, Tolerability and Effects of L-Arginine in Boys With Dystrophinopathy on Corticosteroids L-arginine - Dystrophinopathy, Duchenne Muscular Dystrophy | Phase 1 | Completed | Massachusetts General Hospital | 7 | 2012-01-01 | 2012-07-03 |
| Improved Muscle Function in Duchenne Muscular Dystrophy Through L-Arginine and Metformin Metformin, L-Arginine - Duchenne Muscular Dystrophy | Phase 1 | Completed | University Hospital, Basel, Switzerland | 5 | 2012-01-01 | 2015-08-07 |
| Prospective L-arginine Study L-arginine - Heart Transplant | Phase 1 | Terminated | University of Michigan | 3 | 2011-07-01 | 2017-01-10 |
| Supplementation of L-arginine in Patients With Non-resectable Brain Metastases L-arginine hydrochloride solution, Placebo - Unresectable Multiple Brain Metastases | Phase 1 / Phase 2 | Completed | Instituto de Oncología Ángel H. Roffo | 70 | 2004-05-01 | 2016-07-28 |
| Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia Hydroxyurea, L-Arginine, Sildenafil - Sickle Cell Anemia | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 39 | 2003-03-10 | 2019-11-22 |
| Treatment of Supine Hypertension in Autonomic Failure Clonidine, Nitroglycerin transdermal, Dipyridamole/ Aspirin (Aggrenox) - Hypertension | Phase 1 | Completed | Vanderbilt University | 152 | 2001-01-01 | 2017-10-13 |
Muscular Dystrophy, Duchenne (2) · Anemia, Sickle Cell (1) · Cardiovascular Diseases (1) · Hypertension (1) · Intermittent Claudication (1) · Multiple System Atrophy (1) · Neoplasms (1) · Peripheral Arterial Disease (1) · Peripheral Vascular Diseases (1) · Pure Autonomic Failure (1) · Shy-Drager Syndrome (1)
Instituto de Oncología Ángel H. Roffo (1) · Louis Messina (1) · Massachusetts General Hospital (1) · National Institutes of Health Clinical Center (CC) (1) · The University of Texas at Arlington (1) · University Hospital, Basel, Switzerland (1) · University of Michigan (1) · Vanderbilt University (1)
United States (6)
Alfredo H Navigante, MD, Phd (1) · Dirk Fischer, MD (1) · Italo Biaggioni, MD (1) · John F Tisdale, M.D. (1) · Louis M Messina, MD (1) · Namita Goyal, MD (1)
PMID 10851208, PMID 11927799, PMID 12119802, PMID 12923400, PMID 15738343, PMID 16391172, PMID 16533484, PMID 18426998, PMID 19047577, PMID 19738158, PMID 22801444, PMID 23266540, PMID 26799743, PMID 9369256, PMID 9890307