5 completed, 3 terminated, 3 unknown, 1 recruiting. 13 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 13 | Completed 5, Terminated 3, Unknown 3, Recruiting 1, Withdrawn 1 |
Follow Hydrocodone: new trials by email Literature Review of Hydrocodone trials Research Report on Hydrocodone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Methylprednisolone for Pain Control After ACL Repair Meloxicam 15 mg, Medrol 4 MG Oral Tablet Includes Medrol Dosepak, Gabapentin 300 mg - ACL Surgery, Pain Management | Phase 4 | Recruiting | St. Louis University | 90 | 2025-10-21 | 2025-10-24 |
| Hydrocodone Compared to Acetaminophen and Ibuprofen for Post-nail Procedure Analgesia Hydrocodone 5Mg/Acetaminophen 325Mg Tab, Acetaminophen 1000mg, Ibuprofen 400 mg - Nail Diseases, Nail Abnormality | Phase 4 | Completed | Weill Medical College of Cornell University | 20 | 2022-11-10 | 2023-09-28 |
| Multimodal Analgesia Effect on Post Surgical Patient Neurontin, Dilaudid Injectable Product, Marcaine Injectable Product - Obesity, Morbid, Surgery | Phase 4 | Completed | University of California, Davis | 60 | 2021-01-20 | 2026-09-14 |
| Postoperative Pain Control in Septum and Sinus Surgery Acetaminophen 325 mg Oral Tablet, Acetaminophen 650 mg Oral Tablet, OxyCODONE 5 mg Oral Tablet - Post-operative Pain, Sinus Surgery | Phase 4 | Completed | Corewell Health East | 65 | 2019-11-27 | 2023-08-31 |
| Narcotic Versus Non-narcotic Medication for Pain Management After Wrist/Hand Fractures Hydrocodone 5Mg/Acetaminophen 500Mg Tab, Acetaminophen 500Mg Tab, Ibuprofen 600 mg tab - Distal Radius Fracture, Pain Management | Phase 4 | Unknown | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 250 | 2019-08-01 | 2021-03-01 |
| US-guided SAPB for Rib Fractures in the ED Bupivacaine, Fentanyl, morphine, hydromorphone, hydrocodone, acetaminophen, ketorolac, gabapentin, ketamine, ibuprofen - Rib Fractures, Rib Fracture Multiple | Phase 4 | Unknown | Andrew A Herring | 70 | 2018-11-06 | 2018-12-19 |
| Effect of Gabapentin on Postoperative Opioid Analgesic Use and Pain in Adolescents Undergoing Tonsillectomy Gabapentin, hydrocodone, acetaminophen and ibuprofen - Pain, Postoperative | Phase 4 | Terminated | Albany Medical College | 17 | 2017-08-04 | 2021-08-27 |
| Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery Acetaminophen, Gabapentin, Orphenadrine - Colon Cancer, Colon Diverticulosis | Phase 4 | Unknown | University of Illinois College of Medicine at Peoria | 80 | 2017-01-01 | 2017-03-20 |
| Post-tonsillectomy Pain Control in Adults Norco (Hydrocodone and Acetaminophen), Percocet (Oxycodone and Acetaminophen), Dilaudid (hydromorphone) - Pain, Postoperative, Postoperative Nausea and Vomiting | Phase 4 | Terminated | University of Nebraska | 27 | 2016-01-01 | 2023-07-13 |
| The Effect of NSAIDs After a Rotator Cuff Repair Surgery. Rotator cuff repair, Ibuprofen, Hydrocodone/Acetaminophen, Omeprazole, Hydrocodone/Acetaminophen - Rotator Cuff Tear | Phase 4 | Withdrawn | University of Chicago | 2015-01-01 | 2023-02-23 | |
| Patient Satisfaction With Pain Relief After Ambulatory Hand Surgery Acetaminophen, Vicodin - Carpal Tunnel Syndrome | Phase 4 | Terminated | Massachusetts General Hospital | 7 | 2012-07-01 | 2017-03-14 |
| Pharmacokinetic Study of Hydrocodone/APAP in Chronic Pain Patients Hydrocodone - Chronic Pain | Phase 4 | Completed | NEMA Research, Inc. | 30 | 2012-02-01 | 2016-07-28 |
| A Comparison of the Addiction Liability of Hydrocodone and Sustained Release Morphine Markers of Abuse Liability, Neuropsych Testing, and Cue Reactivity, ER Morphine, hydrocodone plus acetaminophen - Chronic Pain | Phase 4 | Completed | University of California, Davis | 12 | 2005-11-01 | 2017-05-30 |
Agnosia (5) · Pain, Postoperative (4) · Chronic Pain (2) · Pain (2) · Body Weight Changes (1) · Carpal Tunnel Syndrome (1) · Colonic Neoplasms (1) · Constipation (1) · Diverticulitis, Colonic (1) · Diverticulosis, Colonic (1) · Emergencies (1) · Ileus (1) · Nail Diseases (1) · Nails, Malformed (1) · Obesity, Morbid (1)
University of California, Davis (2) · Albany Medical College (1) · Andrew A Herring (1) · Corewell Health East (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Massachusetts General Hospital (1) · NEMA Research, Inc. (1) · St. Louis University (1) · University of Chicago (1) · University of Illinois College of Medicine at Peoria (1) · University of Nebraska (1) · Weill Medical College of Cornell University (1)
United States (11) · Canada (1)
Andrew Herring, MD (1) · Arun Nagdev, MD (1) · Barbara Jachniewicz, MSN, CRNFA, (1) · Barth L Wilsey, MD (1) · Daniel Mantuani, MD, MPH (1) · David C Ring, MD PhD (1) · David Seel, DO. (1) · Eben Clattenburg, MD (1) · Joseph Pergolizzi, MD (1) · Josh Luftig, PA (1) · Joy C MacDermid, PhD (1) · Lewis L Shi, MD (1) · Mohamed R Ali, MD, FACS (1) · Samuel Pate, M.D. (1) · Scott Kaar, MD (1)
PMID 19135997, PMID 19209273, PMID 19535182, PMID 19660492, PMID 37619705