12 completed, 5 recruiting, 3 unknown, 1 active not recruiting. 20 Not applicable, 2 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 20 | Completed 10, Recruiting 5, Unknown 3, Active not recruiting 1, Not yet recruiting 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 2 | Completed 2 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mitigation of Health Effects in Pregnant Women by Reducing Exposure to Heat and Air Pollution Heat intervention, Heat and air pollution mitigation intervention - Sleep Quality | Not applicable | Recruiting | University of Cyprus | 102 | 2026-05-01 | 2026-06-05 |
| Mitigation of Health Effects in Older Adults With Hypertension by Reducing Exposure to Heat and Air Pollution Heat intervention, Heat and air pollution mitigation intervention - Hypertension Arterial, 65 Years Older | Not applicable | Recruiting | University of Cyprus | 102 | 2026-05-01 | 2026-06-05 |
| Mitigation of Health Effects in Outdoor Workers by Reducing Exposure to Heat and Air Pollution Heat intervention, Heat and air pollution mitigation intervention - Heat Strain | Not applicable | Recruiting | University of Cyprus | 102 | 2026-05-01 | 2026-06-16 |
| A New Model to Induce Itch and Inflammation Cowhage (Mucuna Pruriens), Histamine, Heat - Itching | Not applicable | Not yet recruiting | Aalborg University | 28 | 2026-02-15 | 2026-02-11 |
| Thermal Therapies in the Treatment of Muscle Injuries Cold water immersion, Hot water immersion, Physiotherapy only - Hamstring Injuries, Hamstring Muscle Repair | Not applicable | Recruiting | Aspetar | 135 | 2025-09-01 | 2026-10-28 |
| Study to Assess the Effectiveness of a Heat Risk Reduction Decision Support Platform and the Barriers and Facilitators of Its Implementation With 30 US Local Health Department Sites Online decision support platform to support evidence-based heat health risk assessment and extreme heat event preparedness planning, Heat and health risk assessment and preparedness information - Extreme Heat, Heat Health | Not applicable | Active not recruiting | University of Washington | 30 | 2025-08-01 | 2026-06-11 |
| Effect of Pelvic Floor-Based Training on Dysmenorrhea Education and exercise, Self-method like resting or heat - Dysmenorrhea | Not applicable | Unknown | Uskudar University | 70 | 2024-08-20 | 2024-09-19 |
| Evaluating Pathophysiological Mechanisms of Acute and Chronic Heat Stress on Maternal and Fetal Health Heat and Physical Work Exposure Protocol - Thermally Neutral Condition With Light-intensity Work, Thermally Neutral Condition With Moderate-intensity Work | Not applicable | Completed | University of Thessaly | 24 | 2024-05-15 | 2026-01-08 |
| Effect of a 16-day Hot and Cold Acclimation on Adaptive Responses and Health-related Indicators 16-day hot and cold acclimation - Healthy | Not applicable | Recruiting | Lithuanian Sports University | 31 | 2024-04-04 | 2024-04-15 |
| Early Weaning From Incubator To Crib Weaning incubator (heat) at an lower postnatal weight - Hypothermia, Newborn, Body Temperature Changes | Not applicable | Unknown | Augusta University | 50 | 2023-07-21 | 2024-02-07 |
| Effects of Acute Pain on Cognitive Performance in Young Adults pain delivery with capsaicin and heat, distractor delivery with sensory TENS - Pain, Acute, Cognition | Not applicable | Completed | University of Delaware | 23 | 2023-03-22 | 2023-12-11 |
| Cardiovascular Responses to Heat Waves in the Elderly Hot and Humid Trial, Hot and Dry Trial - Aging, Hyperthermia | Not applicable | Completed | University of Texas Southwestern Medical Center | 59 | 2021-01-19 | 2025-10-23 |
| Hot and Cold Compress in Hemodialysis Hot and Cold compress, nursing interventions - Hemodialysis Complication, Muscle Spasm | Not applicable | Completed | Hacettepe University | 69 | 2020-02-01 | 2020-12-23 |
| Radial Artery Vasodilation Heat Study Topical Heat - Radial Artery | Phase 1 / Phase 2 | Completed | Oregon Health and Science University | 45 | 2018-08-03 | 2019-09-25 |
| The Effect of Exercise on Recent Onset Low Back Pain in the Emergency Department Exercise, Advice to stay active and engaged in usual activities., Advice on use of ice or heat - Low Back Pain | Not applicable | Completed | Queen's University | 69 | 2018-05-01 | 2019-03-25 |
| Quantitative Sensory Testing in Chronic Pain Patients Undergoing Opioid Treatment and Opioid Tapering sensory testing (Heat, cold, and pressure), Promis Survey - Analgesic Drug Dependence, Sensory Deficit | Not applicable | Completed | The University of Texas Medical Branch, Galveston | 43 | 2017-12-22 | 2024-02-13 |
| Bed Baths' Impact on Blood Gases and Vital Signs in Children bed bath, bed bath with heat - Vital, Blood Gases | Not applicable | Completed | Nuh Naci Yazgan University | 12 | 2015-12-15 | 2025-03-12 |
| Heat & Aerobic Training (HEAT) Study Heat & Aerobic Training (HEAT), Exercise Only - Pre-hypertension | Not applicable | Completed | University of Illinois at Urbana-Champaign | 41 | 2015-08-21 | 2019-04-17 |
| Applied Topical Heat as an Adjunct for Pain Control in First-Trimester Surgical Abortionl heat - Topical Heat Application for Intraoperative Abortion Pain Management | Not applicable | Completed | Planned Parenthood of Greater New York | 120 | 2015-07-01 | 2016-09-29 |
| Phase 1/2 Study of ThermoDox With Approved Hyperthermia in Treatment of Breast Cancer Recurrence at the Chest Wall ThermoDox in combination with Microwave Hyperthermia (heat) - Breast Cancer | Phase 1 / Phase 2 | Completed | Imunon | 17 | 2013-02-01 | 2017-01-30 |
Showing 20 of 22. Sign in to see all of them.
Hyperthermia (3) · Hypertension (2) · Acute Pain (1) · Aneurysm (1) · Body Temperature Changes (1) · Breast Neoplasms (1) · Dysmenorrhea (1) · Emergencies (1) · Fatigue (1) · Fever (1) · Heat Stress Disorders (1) · Hypothermia (1) · Low Back Pain (1) · Motor Activity (1) · Muscle Cramp (1)
University of Cyprus (3) · Aalborg University (1) · Aspetar (1) · Augusta University (1) · Bispebjerg Hospital (1) · Hacettepe University (1) · Imunon (1) · Lithuanian Sports University (1) · Nuh Naci Yazgan University (1) · Oregon Health and Science University (1) · Planned Parenthood of Greater New York (1) · Queen's University (1) · Stony Brook University (1) · The University of Texas Medical Branch, Galveston (1) · University of Delaware (1)
United States (10) · Cyprus (2) · Denmark (2) · Greece (2) · Spain (2) · Turkey (Türkiye) (2) · Canada (1) · Italy (1) · Lithuania (1) · Qatar (1)
Panayiotis Yiallouros, Professor (3) · Cebrail Cebrailov, M.D. (1) · Denise Wilkes, MD-PhD (1) · Elizabeth Blackmore, MD (1) · Hans C Wulf, MD, Sci (1) · Jeremy Hess, MD, MPH (1) · Jordan Miller, PhD (1) · Leonidas Ioannou, PhD (1) · Nicholas Borys, MD (1) · Ramsey Al-Hakim, MD (1)
PMID 16229972, PMID 18989788, PMID 21029354, PMID 21412369, PMID 22570562, PMID 22704854, PMID 23340535, PMID 25144817, PMID 25437498, PMID 26469365, PMID 26685018, PMID 27898461, PMID 27908840, PMID 27993558, PMID 28402092, PMID 41310808, PMID 41927202, PMID 8815179
P20ES036748 (1), R01AG069005 (1), R01AG071585 (1)