41 completed, 6 recruiting, 4 unknown, 2 active not recruiting. 55 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 55 | Completed 41, Recruiting 6, Unknown 4, Active not recruiting 2, Not yet recruiting 1, Terminated 1 |
Follow Fructose: new trials by email Literature Review of Fructose trials Research Report on Fructose
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fructose and (Aging) Fructose, Glucose - Intestinal Permeability, Immune Response | Not applicable | Recruiting | University of Vienna | 32 | 2026-04-01 | 2026-08-11 |
| Effects of Dual-Source Carbohydrate Intake and Liver Glycogen Repletion After Overnight Fasting. No breakfast, Breakfast (0% Fructose), Breakfast (50% fructose) - Carbohydrate Metabolism, Hepatic Glycogen Storage | Not applicable | Not yet recruiting | Manchester Metropolitan University | 12 | 2026-03-01 | 2026-03-17 |
| Glucose-fructose Ratio Pilot Glucose and fructose (one-to-one), Glucose and fructose (two-to-one) - Exercise Metabolism | Not applicable | Completed | University of Bath | 11 | 2026-01-14 | 2026-10-26 |
| Effect of Low Dose Galactose on Glycaemia and Glucose Kinetics galactose, fructose, Glucose Powder - Glucose | Not applicable | Recruiting | University of Bath | 25 | 2026-01-01 | 2026-07-08 |
| Fructose is a Metabolic and Inflammatory Pathogenic Factor in Metabolic Dysfunction-associated Steatohepatitis (MASH) fructose, glucose - MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis | Not applicable | Recruiting | Queen Mary University of London | 72 | 2025-06-30 | 2026-07-31 |
| Dietary Treatment Strategies and Metabolic Control in Glycogen Storage Disease Type I Fructose, Fructose and galactose - Glycogen Storage Disease Type I | Not applicable | Recruiting | Insel Gruppe AG, University Hospital Bern | 20 | 2025-04-24 | 2026-05-12 |
| Assessments of Metabolic Responses to Acute Oral Administration of Sucrose, Glucose, and Fructose Sucrose, Glucose, Fructose - Gastrointestinal Hormones, Glycemic Control | Not applicable | Active not recruiting | University Hospital, Basel, Switzerland | 20 | 2025-02-06 | 2026-09-03 |
| Ketosis Impact on Signs & Symptoms of Schizophrenia and Bipolar disorderS (R)-3-hydroxybutyl (R)-3-hydroxybutyrate), Maltodextrin, Fructose, Pectin, Sodium alginate, Sodium chloride - Schizophrenia and Related Disorders, Psychosis | Not applicable | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 28 | 2024-12-01 | 2026-04-27 |
| High Fructose Diet, the Gut Microbiome, and Metabolic Health Fructose, glucose - MASLD, Type 2 Diabetes | Not applicable | Recruiting | Icahn School of Medicine at Mount Sinai | 30 | 2024-10-08 | 2025-12-17 |
| The Role of Sugars in Fat Accumulation in the Liver 150g of fat with glucose, 150g of fat with fructose, 150g of fat with sucrose - Fatty Liver Disease | Not applicable | Recruiting | Institute for Clinical and Experimental Medicine | 40 | 2024-06-20 | 2024-12-30 |
| Exogenous Ketosis During Bed Rest in Older Adults ketone monoester (R)-3-hydroxybutyl (R)-3- hydroxybutyrate, carbohydrate-fat placebo (fructose, corn and canola oil 50:50 ratio) - Muscle Protein Synthesis, Muscle Atrophy | Not applicable | Completed | McGill University | 30 | 2023-02-27 | 2024-02-07 |
| BaRiatric Surgery AnD FRUctose Handeling In Obese subjecTs fructose - Insulin Resistance | Not applicable | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 20 | 2023-02-05 | 2023-02-08 |
| A Pilot Study to Determine Fructose Uptake by Primary Human Colorectal Tumors Cohort 1: HFCS (fructose) fed, Cohort 2: D-Xylose (xylose-fed) - Colorectal Tumors | Not applicable | Completed | Weill Medical College of Cornell University | 12 | 2022-02-16 | 2024-11-06 |
| Effect of Daily Erythritol Versus Sucrose Intake Over 5 Weeks on Glucose Tolerance in Adolescents Erythritol, Sucrose, Glucose - Insulin Resistance, Glucose Tolerance | Not applicable | Active not recruiting | University Hospital, Basel, Switzerland | 30 | 2021-08-18 | 2026-09-30 |
| Effects of Rehydration During Physical Exercise on Acute Kidney Injury Biomarkers Fructose/glucose/xylitol/saccharose - Acute Kidney Injury | Not applicable | Unknown | Medical University of Gdansk | 30 | 2020-03-09 | 2020-03-17 |
| Fructose in Exercising Individuals With Type 1 Diabetes Using Insulin Degludec Fructose, Plain water - Type 1 Diabetes Mellitus, Diabetes Complications | Not applicable | Completed | Insel Gruppe AG, University Hospital Bern | 15 | 2019-01-04 | 2019-09-20 |
| Vascular and Metabolic Consequences of Adopting a Westernized Lifestyle Fructose and physical inactivity - Vascular Diseases | Not applicable | Completed | University of Missouri-Columbia | 52 | 2018-11-30 | 2022-08-17 |
| Fructose-induced Hepatic De Novo Lipogenesis in Adolescents With Obesity Fructose + Glucose Beverage - Adolescent Obesity | Not applicable | Terminated | The Rogosin Institute | 12 | 2018-08-13 | 2024-03-15 |
| Fructose Rich Diet and Endothelial Function Fructose, Glucose, Fructose and exercise - Fructose Metabolism Disorder, Fructose Rich Diet | Not applicable | Completed | Federal University of Rio Grande do Sul | 21 | 2018-06-01 | 2019-05-06 |
| Effects of Fructose Restriction on Liver Steatosis Glucose, Fructose - Nonalcoholic Fatty Liver Disease, Glucose Metabolism Disorders | Not applicable | Completed | Maastricht University Medical Center | 44 | 2017-01-31 | 2020-02-21 |
Showing 20 of 55. Sign in to see all of them.
Insulin Resistance (7) · Dyslipidemias (4) · Non-alcoholic Fatty Liver Disease (4) · Diabetes Mellitus, Type 2 (3) · Exploratory Behavior (3) · Metabolic Syndrome (3) · Sedentary Behavior (3) · Diabetes Mellitus, Type 1 (2) · Fatty Liver (2) · Hypertriglyceridemia (2) · Inflammation (2) · Irritable Bowel Syndrome (2) · Motor Activity (2) · Obesity (2) · Overweight (2)
University Hospital, Basel, Switzerland (5) · University of Lausanne (3) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (2) · Federal University of Rio Grande do Sul (2) · Insel Gruppe AG, University Hospital Bern (2) · Institute for Clinical and Experimental Medicine (2) · The Rogosin Institute (2) · Unilever R&D (2) · Universitaire Ziekenhuizen KU Leuven (2) · University of Bath (2) · University of California, Davis (2) · University of Nottingham (2) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (1) · Brain-Gut Research Group (1) · Hvidovre University Hospital (1)
Switzerland (11) · United States (9) · United Kingdom (7) · Canada (5) · Netherlands (5) · Austria (2) · Brazil (2) · Czechia (2) · Sweden (2) · China (1) · Denmark (1) · Finland (1) · Italy (1) · New Zealand (1) · Poland (1)
Christoph Beglinger, MD (2) · Kimber L Stanhope, Ph.D, R.D. (2) · Lisa Hudgins, MD (2) · Luc Tappy, MD (2) · Anne Christin Meyer-Gerspach, PD, PhD (1) · Camila Manrique Acevedo, MD (1) · Christoph Beglinger, Prof (1) · Christoph Stettler, MD (1) · David Green (1) · Dita Pajuelo, PhD (1) · Duo Li, Doctor (1) · Giles AD Major, BM BCh MA MRCP (1)
PMID 21252253, PMID 21613559, PMID 21677052, PMID 21956423, PMID 22933433, PMID 23034968, PMID 25879513, PMID 25904601, PMID 26537945, PMID 26674497, PMID 26702120, PMID 27746233, PMID 28100512, PMID 28350714, PMID 29722834, PMID 29806553, PMID 29890724, PMID 30844053, PMID 31136656, PMID 31288630, PMID 31365624, PMID 31796953, PMID 32558624, PMID 32591421, PMID 32875733, PMID 32916151, PMID 33381794, PMID 34265055, PMID 36040803, PMID 36184254, PMID 36338481, PMID 38969065, PMID 40414296, PMID 40568354, PMID 40721209, PMID 42833446
R01DK137968 (1), R01HL075675 (1), R01HL091333 (1), R01HL107256 (1)