12 completed, 6 unknown. 18 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 18 | Completed 12, Unknown 6 |
Follow Fluorides: new trials by email Literature Review of Fluorides trials Research Report on Fluorides
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Different Remineralizing Agents on White Spot Lesions Treatment in Children Casein phosphopeptide-amorphous calcium phosphate, Casein phosphopeptide-amorphous calcium phosphate + fluoride, Nano hydroxyapatite paste - White Spot Lesion of Tooth | Not applicable | Completed | National Research Centre, Egypt | 100 | 2024-12-01 | 2025-02-12 |
| Maintaining Oral Health With Bio-products Mouth rinse 1, Mouth rinse 2, Mouth rinse 3 - Dental Caries, Dental Erosion | Not applicable | Completed | University of Bern | 12 | 2024-11-01 | 2025-09-23 |
| Effect of an Experimental Gel Based on Acmella Oleracea Extract Associated or Not With Fluoride on Dentin Hypersensitivity CT- control group, NP- Potassium nitrate gel, AO - Acmella Oleracea Extract Gel - Dentin Desensitizers, Non-carious Cervical Lesions | Not applicable | Completed | Universidade Federal do Para | 100 | 2024-08-20 | 2025-05-21 |
| Effects of Different Remineralization Agents on Molar Incisor Hypomineralization Defects: a Randomized Clinical Study Fluoride - Molar Incisor Hypomineralization | Not applicable | Unknown | Universidad Nacional Autonoma de Mexico | 100 | 2024-03-01 | 2024-04-12 |
| Dentine Hypersensitivity Treated With Laser and Fluoride. Laser and Fluoride, Fluoride - Sensitive Dentin | Not applicable | Unknown | University of Pavia | 43 | 2024-01-15 | 2024-02-20 |
| Assessment of the Cytotoxic and Genotoxic Effect of Toothpastes With Different Forms of Fluoride on the Buccal Mucosa Toothpaste without fluoride, Toothpaste with sodium fluoride, Toothpaste with sodium monofluorophosphate - DNA Damage | Not applicable | Unknown | University of Zagreb | 80 | 2022-11-01 | 2022-10-27 |
| Evaluation of Caries Prevention Based on Genetic Etiology and Risk. Fluoride - Caries,Dental | Not applicable | Unknown | Umeå University | 520 | 2021-08-25 | 2022-10-31 |
| Remineralization Potential of Curodont Repair Flouride Plus Versus CPP-ACP in Management of White Spot Lesions: Randomized Clinical Trial Self assembling peptide with fluoride - White Spot Lesion | Not applicable | Unknown | Cairo University | 48 | 2020-02-01 | 2020-01-29 |
| The Anticariogenic Effect of Miswak (Silvadora Persica) and Grape Seed Extract Miswak, Grape Seed Extract Mouthwash, fluoride - Dental Caries | Not applicable | Completed | Al-Azhar University | 30 | 2019-06-01 | 2019-10-23 |
| Remineralization Potential of MI Varnish Versus Fluoride Varnish on White Spot Lesions in Maxillary Primary Incisors MI varnish - Remineralization Effect of the Varnish on White Spot Lesions | Not applicable | Completed | Cairo University | 60 | 2019-03-01 | 2020-07-21 |
| Miswak Versus Standard Measures to Prevent the Incidence of Caries Young Egyptian Adults: A Randomized Controlled Clinical Trial miswak stick, Miswak plus tooth brushing and tooth paste, Standard preventive measures (tooth brushing , interdental cleaning and mouth rinse use containing CHX and Fluoride) - Dental Caries | Not applicable | Unknown | Cairo University | 82 | 2019-01-01 | 2020-02-25 |
| Fissure Caries Inhibition Study With Solea CO2-9.3μm Short-pulsed Laser Laser, Fluoride - Dental Caries | Not applicable | Completed | University of California, San Francisco | 60 | 2018-02-08 | 2021-01-28 |
| Effect of Different Pastes on Remineralization of Early Caries Lesions in Primary Teeth CPP-ACP paste, Fluoride toothpaste, Both (Fluoride and CPP-ACP) - White Spot Lesion of Tooth | Not applicable | Completed | Jordan University of Science and Technology | 118 | 2016-03-01 | 2018-05-16 |
| Antimicrobial Effect of Different Pastes on Streptococcus Mutans in Children CPP-ACP paste, Fluoride toothpaste, Both (Fluoride and CPP-ACP) - Mutans Streptococci, Oral Health | Not applicable | Completed | Jordan University of Science and Technology | 127 | 2016-03-01 | 2018-05-16 |
| Cytogenetic Damage in Buccal Cells Caused by Toothpaste Toothpaste non-fluoride and fluoride - Toxicity | Not applicable | Completed | University of Split, School of Medicine | 40 | 2016-01-01 | 2017-10-30 |
| The Effect of Experimental Dentifrices on Remineralization of Caries Lesions In-situ Sodium fluoride (1426 ppm), Sodium fluoride (1150 ppm), Sodium fluoride (250 ppm) - Oral Hygiene | Not applicable | Completed | GlaxoSmithKline | 62 | 2014-06-01 | 2015-05-01 |
| Compare the Efficacy of the Remineralization Agents on the White Enamel Lesions Clinpro White Varnish (fluoride + calcium varnish), Curodont Repair - White Spot Lesions | Not applicable | Completed | Ege University | 32 | 2013-08-01 | 2016-07-21 |
| Triclosan Toothpaste and Third Molar Surgery Colgate Total Toothpaste, Colgate Regular Toothpaste - Dry Socket, Wound Infection | Not applicable | Completed | University of Rochester | 141 | 2008-02-01 | 2015-10-28 |
Dental Caries (5) · Dentin Sensitivity (2) · Dry Socket (1) · Molar Hypomineralization (1) · Tooth Erosion (1) · Wound Infection (1)
Cairo University (3) · Jordan University of Science and Technology (2) · Al-Azhar University (1) · Ege University (1) · GlaxoSmithKline (1) · National Research Centre, Egypt (1) · Umeå University (1) · Universidad Nacional Autonoma de Mexico (1) · Universidade Federal do Para (1) · University of Bern (1) · University of California, San Francisco (1) · University of Pavia (1) · University of Rochester (1) · University of Split, School of Medicine (1) · University of Zagreb (1)
Egypt (5) · United States (3) · Jordan (2) · Brazil (1) · Croatia (1) · Italy (1) · Mexico (1) · Sweden (1) · Switzerland (1) · Turkey (Türkiye) (1)
Ola Al-Batayneh, MDSc, FRACDS (2) · Andrea Scribante, DDS PhD MSc (1) · Cecy M Silva (1) · Ece Eden (1) · Ecem Ergin (1) · Maha Niazy, Professor (1) · Mohamed F Rashed, Researcher (1) · Nicklas Stromberg, Prof (1) · Peter Rechmann, DDS, PhD (1) · Thiago S Carvalho, PD Dr (1) · Yanfang Ren, DDS, MPH (1)
PMID 29191562, PMID 32803438, PMID 39096337, PMID 40830200, PMID 42693341