9 completed, 2 recruiting, 2 withdrawn, 1 terminated. 15 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 15 | Completed 9, Recruiting 2, Withdrawn 2, Terminated 1, Unknown 1 |
| Phase 2 | 5 | Completed 4, Unknown 1 |
Follow Famotidine: new trials by email Literature Review of Famotidine trials Research Report on Famotidine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Novel Strategies for Reducing Burn Scar Itch Famotidine and 4% topical cromolyn sodium, Placebo - Burn Scar, Itch Scarring | Phase 3 | Recruiting | The University of Texas Medical Branch, Galveston | 44 | 2025-03-01 | 2026-10-05 |
| Multimodal Pain Package vs. Regular Formulation for Pain Management in Ambulatory Spinal Surgery Acetaminophen, Celebrex, Gabapentin - Spinal Disorder | Phase 3 | Withdrawn | University of Miami | 2024-06-01 | 2025-06-03 | |
| Treatment of Long CoronaVirus Disease (COVID) (TLC) Feasibility Trial Cetirizine, Famotidine, Cetirizine Placebo - COVID-19 | Phase 3 | Terminated | Emory University | 5 | 2024-03-08 | 2025-07-17 |
| Interest of Famotidine in Children With Sickle Cell Disease Famotidine 400 mg/50 mL - Sickle Cell Disease | Phase 2 / Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 30 | 2022-01-12 | 2025-10-08 |
| Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel Cimetidine, Dexamethasone, Diphenhydramine - Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | Phase 2 / Phase 3 | Completed | Ohio State University Comprehensive Cancer Center | 130 | 2021-10-07 | 2025-08-20 |
| Combined Antihistaminics Therapy in COVID 19 Patients Loratadine, Famotidine - Covid19 | Phase 2 / Phase 3 | Completed | Ain Shams University | 214 | 2021-09-13 | 2023-08-25 |
| Role of Famotidine in the Clinical Improvement of COVID-19 Patients. Famotidine 20 MG - Covid19 | Phase 3 | Completed | Chattogram General Hospital | 208 | 2020-08-01 | 2021-10-26 |
| Antihistamines in the Treatment of Irritable Bowel Syndrome With Diarrhea Antihistamine, Placebo - Irritable Bowel Syndrome, Dermatographism | Phase 3 | Withdrawn | University of Cincinnati | 2020-02-01 | 2026-09-04 | |
| PPI Versus Histamine Antagnists as Adjuvant to Chemotherapy CHOP, CHOP Plus Lanzoprazole, CHOP Plus Famotidine - Lymphoma | Phase 3 | Recruiting | Sherief Abd-Elsalam | 60 | 2018-08-01 | 2018-08-27 |
| Famotidine in Schizophrenia Famotidine, Placebo - Schizophrenia | Phase 2 / Phase 3 | Unknown | Jesper Ekelund | 140 | 2014-03-01 | 2015-04-14 |
| A Multi-center, Randomized, Double-blind Phase III Clinical Trial to Assess and Compare to the Efficacy and Safety of Lafutidine, Famotidine and Omeprazole-referenced in Korean Erosive Esophagitis Patients Lafutidine, Famotidine, Omeprazole - Erosive Esophagitis | Phase 3 | Completed | Boryung Pharmaceutical Co., Ltd | 495 | 2011-11-01 | 2025-01-15 |
| ASP (PPI_H2RA) Study-H2RA Versus PPI for the Prevention of Recurrent UGIB in High-risk Users of Low-dose ASA Rabeprazole, Famotidine - Upper Gastrointestinal Bleeding | Phase 3 | Completed | Chinese University of Hong Kong | 264 | 2011-01-01 | 2017-04-21 |
| Efficacy and Safety Study of HZT-501 in Subjects Requiring Nonsteroidal Anti-Inflammatory Drug (NSAID) Treatment Ibuprofen/famotidine, Ibuprofen - Ulcer | Phase 3 | Completed | Amgen | 906 | 2007-03-01 | 2024-12-16 |
| Famotidine in Subjects With Non-erosive Gastroesophageal Reflux Disease Famotidine - Gastroesophageal Reflux | Phase 2 / Phase 3 | Completed | Astellas Pharma Inc | 480 | 2005-09-01 | 2011-11-21 |
| Verification Study on Lafutidine in Mild Reflux Oesophagitis - Double Blind Controlled Study With Famotidine - Lafutidine, Famotidine, Placebo - Gastroesophageal Reflux | Phase 3 | Completed | Taiho Pharmaceutical Co., Ltd. | 325 | 2005-04-01 | 2011-07-07 |
COVID-19 (3) · Gastroesophageal Reflux (2) · Anemia, Sickle Cell (1) · Arthritis (1) · Arthritis, Rheumatoid (1) · Breast Carcinoma In Situ (1) · Breast Neoplasms (1) · Burns (1) · Complex Regional Pain Syndromes (1) · Esophagitis, Peptic (1) · Familial dermographism (1) · Gastrointestinal Diseases (1) · Gastrointestinal Hemorrhage (1) · Irritable Bowel Syndrome (1) · Lymphoma (1)
Ain Shams University (1) · Amgen (1) · Assistance Publique - Hôpitaux de Paris (1) · Astellas Pharma Inc (1) · Boryung Pharmaceutical Co., Ltd (1) · Chattogram General Hospital (1) · Chinese University of Hong Kong (1) · Emory University (1) · Jesper Ekelund (1) · Ohio State University Comprehensive Cancer Center (1) · Sherief Abd-Elsalam (1) · Taiho Pharmaceutical Co., Ltd. (1) · The University of Texas Medical Branch, Galveston (1) · University of Cincinnati (1) · University of Miami (1)
United States (4) · Japan (3) · Egypt (2) · Bangladesh (1) · Finland (1) · France (1) · Hong Kong (1) · Sweden (1)
Celeste Finnerty, PhD (1) · David Bernstein, MD (1) · Francis KL Chan, MD (1) · Jesper Ekelund, MD, PhD (1) · Michael J Berger, Pharm.D. (1) · Sahar K Hegazy, Prof (1) · Sahar M El-Haggar, prof (1) · Sang Woo Lee (1) · Suzan A Alhassanin, Ph D (1)
PMID 20379093, PMID 26165391, PMID 27641510, PMID 33394214, PMID 37722599