5 completed, 2 unknown, 1 not yet recruiting, 1 withdrawn. 9 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Completed 5, Unknown 2, Not yet recruiting 1, Withdrawn 1 |
| Phase 2 | 5 | Unknown 2, Completed 1, Not yet recruiting 1, Withdrawn 1 |
Follow esmolol: new trials by email Literature Review of esmolol trials Research Report on esmolol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| POCUS-Guided Esmolol in Septic Shock: A Pilot RCT Esmolol - Septic Shock | Phase 1 / Phase 2 | Not yet recruiting | John Basmaji | 100 | 2026-01-15 | 2026-01-06 |
| Esmolol Versus Lidocaine on the Quality of Postoperative Recovery in Patients Undergoing Functional Endoscopic Sinus Surgery Esmolol Injection, Lidocaine IV - Chronic Rhinosinusitis, Enhanced Recovery After Surgery | Phase 1 / Phase 2 | Unknown | The Second People's Hospital of Huai'an | 60 | 2023-11-21 | 2024-06-13 |
| Dexmedetomidine and Esmolol Early Post Operative Cognitive Dysfunction Esmolol Hydrochloride, Dexmedetomidine - Cognitive Dysfunction | Phase 1 / Phase 2 | Unknown | Beni-Suef University | 58 | 2019-04-01 | 2019-03-27 |
| Study to Compare Pharmacokinetics & Pharmacodynamics of Warfarin & Esmolol in the Absence & Presence of MEDI0382 MEDI0382, Warfarin, Esmolol - Healthy Volunteers | Phase 1 | Completed | MedImmune LLC | 22 | 2017-11-27 | 2018-04-25 |
| Clinical Investigation of Galnobax® for the Treatment of Diabetic Foot Ulcers Esmolol hydrochloride, Placebo gel - Diabetic Foot Ulcer | Phase 1 / Phase 2 | Completed | Novalead Pharma Private Limited | 44 | 2014-02-20 | 2024-05-20 |
| Nicardipine vs Esmolol Craniotomy Emergence Nicardipine, Esmolol - Brain Tumors | Phase 1 | Completed | Northwestern University | 40 | 2013-09-01 | 2014-08-29 |
| Long-term PK and Safety/Tolerability Testing LDLL600 Against Esmolol in Healthy Volunteers LDLL600, Brevibloc - Healthy | Phase 1 | Completed | AOP Orphan Pharmaceuticals AG | 14 | 2012-12-01 | 2015-04-21 |
| A Pharmacokinetic, Pharmacodynamic, Safety Study With AOP LDLA202, ONO LDL50 and Esmolol in Healthy Volunteers LDLA202, ONO LDL50, Esmolol hydrochloride - Healthy | Phase 1 | Completed | AOP Orphan Pharmaceuticals AG | 12 | 2012-07-01 | 2012-09-05 |
| Controlling Hyperadrenergic Activity in Neurologic Injury Esmolol, Propranolol - Traumatic Brain Injury, Dysautonomia | Phase 1 / Phase 2 | Withdrawn | Johns Hopkins University | 2011-07-01 | 2017-04-20 |
Autonomic Nervous System Diseases (1) · Brain Injuries (1) · Brain Injuries, Traumatic (1) · Brain Neoplasms (1) · Cognitive Dysfunction (1) · Diabetes Mellitus, Type 2 (1) · Diabetic Foot (1) · Shock, Septic (1)
AOP Orphan Pharmaceuticals AG (2) · Beni-Suef University (1) · John Basmaji (1) · Johns Hopkins University (1) · MedImmune LLC (1) · Northwestern University (1) · Novalead Pharma Private Limited (1) · The Second People's Hospital of Huai'an (1)
United States (4) · Czechia (2) · China (1) · Egypt (1) · India (1) · Malaysia (1)
Armando Flor (1) · Ivan Ulc, Dr. med. (1) · Ivan Ulc, MD (1) · John Basmaji (1) · John F Bebawy, MD (1) · Vickie R Driver, DPM FACFAS (1) · Wendy Ziai, MD (1)