7 completed, 3 terminated, 1 unknown. 11 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 11 | Completed 7, Terminated 3, Unknown 1 |
Follow enamel matrix proteins: new trials by email Literature Review of enamel matrix proteins trials Research Report on enamel matrix proteins
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Emdogain Adjunctive to Autotransplantation Emdogain (EMD) - test, Sham group - Autotransplantation, Emdogain | Phase 4 | Unknown | Universidad Complutense de Madrid | 20 | 2024-03-12 | 2024-05-09 |
| Root Coverage Using ADM and Coronally Positioned Tunnel With or Without Enamel Matrix Derivative Regenerative tissue matrix and enamel matrix derivative, Regenerative tissue matrix - Recession, Gingival | Phase 4 | Completed | University of Louisville | 24 | 2022-10-06 | 2026-02-10 |
| Comparison of Clinical and Radiographic Parameters in the Application of Cross-linked Hyaluronic Acid 1.8% and Enamel Matrix Derivative in Periodontal Regeneration. Cross-Linked Hyaluronate Gel Prefilled Syringe 30 MG/3ML, Enamel Matrix Proteins (Active comparator group) - Chronic Periodontitis, Periodontal Bone Loss | Phase 4 | Completed | Andres Lopez Roldan | 53 | 2020-03-01 | 2026-08-03 |
| Mandibular Furcation III Regeneration (FURC-III-REGEN) Biphasic calcium phosphate (Straumann Bone Ceramic) + collagen membrane (Straumann Jason Membrane), Biphasic calcium phosphate (Straumann Bone Ceramic) + enamel matrix proteins (Straumann Emdogain) - Furcation Defects, Periodontal Diseases | Phase 4 | Terminated | University of Oslo | 5 | 2019-10-15 | 2023-11-30 |
| Mandibular Furcation II Regeneration Biphasic calcium phosphate (Straumann Bone Ceramic) + collagen membrane (Straumann Jason Membrane), Biphasic calcium phosphate (Straumann Bone Ceramic) + enamel matrix proteins (Straumann Emdogain) - Furcation Defects, Periodontal Diseases | Phase 4 | Terminated | University of Oslo | 5 | 2019-10-15 | 2023-11-30 |
| Emdogain Implementation With Transcrestal Sinus Lifting and Dental Implant Placement Enamel Matrix Protein - Osseointegration Failure of Dental Implant, Bone Density Increased | Phase 4 | Completed | T.C. Dumlupınar Üniversitesi | 24 | 2017-01-01 | 2022-08-18 |
| Enamel Matrix Proteins in the Treatment of Intrabony Defects in Patients With Aggressive and Chronic Periodontitis Enamel Matrix Proteins, Open Flap Debridement - Aggressive Periodontitis | Phase 4 | Completed | University of Campinas, Brazil | 45 | 2016-02-01 | 2018-10-11 |
| EMD and/or Bone Substitute for the Treatment of Class II Furcations EMD, βTCP/HA, Flap access surgery - Periodontal Disease | Phase 4 | Completed | University of Campinas, Brazil | 41 | 2013-03-01 | 2017-03-20 |
| Regenerative Surgical Treatment of Peri-implantitis Emdogain®, Surgery alone - Failure of Dental Implant Due to Infection, Infection | Phase 4 | Completed | Catrine Isehed | 31 | 2008-12-01 | 2016-09-01 |
| Effect of Postsurgical Systemic Doxycycline After Regenerative Periodontal Therapy Doxycycline, Placebo, modified/simplified papilla preservation flap; scaling - Periodontitis | Phase 4 | Terminated | Peter Eickholz | 61 | 2007-04-01 | 2016-11-03 |
| Coronally Advanced Flap in Combination With Acellular Dermal Matrix and Enamel Matrix Derivatives for Root Coverage CAF+ADM+EMD, CAF+ADM - Gingival Recession | Phase 4 | Completed | Tabriz University | 18 | 2006-04-01 | 2008-07-23 |
Periodontal Diseases (4) · Furcation Defects (2) · Gingival Recession (2) · Periodontitis (2) · Aggressive Periodontitis (1) · Alveolar Bone Loss (1) · Bacterial Infections (1) · Chronic Periodontitis (1) · Infections (1) · Inflammation (1) · Mouth Diseases (1) · Osteosclerosis (1) · Peri-Implantitis (1)
University of Campinas, Brazil (2) · University of Oslo (2) · Andres Lopez Roldan (1) · Catrine Isehed (1) · Peter Eickholz (1) · T.C. Dumlupınar Üniversitesi (1) · Tabriz University (1) · Universidad Complutense de Madrid (1) · University of Louisville (1)
Brazil (2) · Norway (2) · Spain (2) · Germany (1) · Iran (1) · Sweden (1) · Turkey (Türkiye) (1) · United States (1)
Bindu Dukka, BDS, MSD, MPH (1) · Deniz Ozbay, DDS PhD (1) · Enilson A Sallum, PhD (1) · Francisco Alpiste Illueca (1) · Pernilla Lundberg, Assoc. Prof (1) · Peter Eickholz, Prof Dr (1) · Reza Pourabbas, DDS (1)
PMID 19254123, PMID 19968743, PMID 22385260, PMID 24059744, PMID 26094684, PMID 32299097, PMID 40106008