38 completed, 23 unknown, 4 not yet recruiting, 3 active not recruiting. 53 Not applicable, 8 Phase 2, 5 Phase 1, 3 Phase 3, 3 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neuroimaging Markers of Midlife Depression and Cognitive Behavioural Therapy (CBT) Cognitive Behavioural Therapy - Major Depressive Disorder (MDD) | Not applicable | Not yet recruiting | Baycrest | 30 | 2026-06-01 | 2026-02-27 |
| AI-Supported Therapy for Depression and Anxiety Compared With Standard CBT AI-Digital CBT, Cognitive Behavioural Therapy - Generalized Anxiety Disorder (GAD), Major Depressive Disorder (MDD) | Not applicable | Not yet recruiting | PsyScale | 400 | 2026-06-01 | 2026-06-04 |
| Ketamine-Enhanced Therapy for Individuals With Alcohol Use Disorder and Depression: A Pilot Study (KET-DUAL) Ketamine, Cognitive Behavioural Therapy - Alcohol Use Disorder (AUD), Major Depressive Disorder (MDD) | Phase 1 / Phase 2 | Not yet recruiting | South West Sydney Local Health District | 20 | 2025-12-10 | 2025-11-25 |
| Disposition Kinetics of Dolutegravir Among People Living With HIV With Major Depression in Nigeria Fluoxetine, Cognitive-behavioral therapy - Depression, HIV | Phase 4 | Not yet recruiting | University of Ibadan | 168 | 2025-08-14 | 2025-08-08 |
| Priming CBT With rTMS for OCD rTMS, CBT - Obsessive Compulsive Disorder (OCD) | Phase 1 | Active not recruiting | Sunnybrook Health Sciences Centre | 10 | 2025-02-05 | 2026-03-04 |
| Interventions Against Fatigue in Patients With Myasthenia Gravis Aerobic exercise therapy, Cognitive behavioural therapy, Usual care - Myasthenia Gravis, Fatigue | Not applicable | Active not recruiting | Leiden University Medical Center | 60 | 2024-12-04 | 2026-07-08 |
| A Blended Psychological Intervention for Depression After Acquired Brain Injury Cognitive Behavioural Therapy - Acquired Brain Injury, Stroke | Not applicable | Unknown | King's College London | 20 | 2023-06-01 | 2023-03-28 |
| Examining the Effectiveness of a Group Cognitive-behavioural Treatment Program for Persistent Genital Arousal Disorder Cognitive behavioural therapy - Persistent Genital Arousal Disorder | Not applicable | Completed | Dr. Caroline Pukall | 8 | 2023-04-24 | 2026-05-06 |
| Prevention of Postpartum Anxiety in High-Risk Women Cognitive Behavioural Therapy - Postpartum Anxiety | Not applicable | Unknown | St. Joseph's Healthcare Hamilton | 30 | 2022-10-01 | 2023-04-14 |
| Can a Self-guided Mobile Phone Application Program Improve Wellbeing in University Students Cognitive Behavioural Therapy, Self-Compassion, Active Control - Perfectionism, Shame | Not applicable | Unknown | National University of Singapore | 400 | 2022-08-01 | 2022-08-02 |
| Long-Term Effects of CBT on Quality of Life in Adults With ADHD cognitive behavioural therapy - Attention Deficit Hyperactivity Disorder | Completed | Amsterdam UMC, location VUmc | 155 | 2022-07-13 | 2024-07-30 | |
| Improve Mental Health and Emotional Labor Among Nurses Who Care the End-of-life Patients cognitive behavioural therapy, mindfulness-based therapy - End-of-life, Depression, Anxiety | Not applicable | Unknown | Huichao Zhang | 100 | 2022-05-01 | 2022-09-15 |
| The Impact of Cognitive Behavioral Therapy for Insomnia (CBT-I) on Glycemic Control in Older Type 2 Diabetes (T2D) Comorbid With Insomnia Cognitive Behavioural Therapy - Diabetes Mellitus, Type 2, Insomnia | Not applicable | Completed | Chinese University of Hong Kong | 214 | 2022-05-01 | 2026-09-11 |
| ICBT for Mental Health Problems Related to the Climate Crisis Cognitive Behavioural Therapy - Depression and Quality of Life | Not applicable | Unknown | Linkoeping University | 120 | 2022-02-07 | 2023-06-27 |
| Cognitive Behavioural Therapy for Youths With Depressive and Anxiety Symptoms in Hong Kong Cognitive Behavioural Therapy - Depressive Symptoms, Anxiety Symptoms | Not applicable | Unknown | The University of Hong Kong | 128 | 2021-09-29 | 2021-10-14 |
| Smartphone-delivered CBT-I Cognitive Behavioural Therapy - Sleep Initiation and Maintenance Disorders | Not applicable | Completed | Karolinska Institutet | 64 | 2021-08-20 | 2023-03-10 |
| Internet-Based Cognitive Behavioural Program for Managing Stress With IBD: An RCT Cognitive Behavioural Therapy - Inflammatory Bowel Diseases, Anxiety | Not applicable | Unknown | University of Manitoba | 352 | 2021-03-16 | 2023-05-11 |
| Group CBT Intervention for Parents of Children With Food Allergy Cognitive Behavioural Therapy - Allergy;Food, Parents | Not applicable | Completed | University of Surrey | 38 | 2021-02-01 | 2022-07-06 |
| Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial Cognitive Behavioural Therapy - Pain, Postoperative, Pain, Acute | Not applicable | Completed | McMaster University | 1024 | 2021-01-25 | 2025-09-05 |
| Cognitive Behavioural Therapy for Sexual Concerns During Perimenopause Cognitive Behavioural Therapy - Perimenopause, Sexual Concerns | Not applicable | Unknown | St. Joseph's Healthcare Hamilton | 62 | 2021-01-01 | 2022-08-23 |
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Depression (15) · Anxiety Disorders (13) · Generalized Anxiety Disorder (6) · Depressive Disorder, Major (5) · Fatigue (4) · Sleep Initiation and Maintenance Disorders (4) · Chronic Pain (3) · Depression, Postpartum (3) · Fractures, Closed (3) · Fractures, Open (3) · Gambling (3) · Pain, Postoperative (3) · Brain Injuries (2) · Dissociative Disorders (2) · Motor Activity (2)
McMaster University (7) · University of Aberdeen (4) · University of Bergen (3) · Charite University, Berlin, Germany (2) · King's College London (2) · Linkoeping University (2) · St. Joseph's Healthcare Hamilton (2) · Sunnybrook Health Sciences Centre (2) · University College, London (2) · Amsterdam UMC, location VUmc (1) · Baycrest (1) · Centre for Addiction and Mental Health (1) · Chinese University of Hong Kong (1) · Colchester East Hants Health Authority (1) · Dan Lubman (1)
Canada (23) · United Kingdom (12) · Norway (8) · Australia (4) · Sweden (4) · Netherlands (3) · Denmark (2) · Germany (2) · Hong Kong (2) · United States (2) · China (1) · Colombia (1) · Egypt (1) · Nigeria (1) · Singapore (1)
Ryan Van Lieshout, MD, PhD (3) · Jason Busse, PhD (2) · Sheila Sprague, PhD (2) · Sheryl M Green, PhD, CPsych (2) · Alan W Gemmill, PhD (1) · Amanda Newton (1) · Anders Hovland, PhD (1) · Anne EM Speckens, PhD, MD (1) · Bjarte Stubhaug, PhD (1) · Carmen L Curcio (1) · Caroline Pukall, PhD (1) · Cheryl Bradbury, Psy. D., C. Psych (1) · Cheryl Harris (1) · Dan Lubman (1) · Dana Dawson, MPhil (1)
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