27 completed. 27 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 27 | Completed 27 |
Follow Cefazolin: new trials by email Literature Review of Cefazolin trials Research Report on Cefazolin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of a Morphomic-Based to the Standard-of-Care-Based Cefazolin Dose for Antimicrobial Prophylaxis Cefazolin for Injection - Surgical Prophylaxis | Phase 4 | Completed | University of Michigan | 57 | 2023-03-08 | 2026-01-30 |
| Early Oral Switch for Uncomplicated Gram-negative Bacteraemia Oral fluoroquinolones (most commonly, ciprofloxacin) or oral trimethoprim-sulfamethoxazole, Standard of care intravenous antibiotics (e.g. ceftriaxone, cefazolin) - Gram-negative Bacteraemia | Phase 4 | Completed | Tan Tock Seng Hospital | 720 | 2022-06-03 | 2026-08-10 |
| A Randomized, Controlled Trial of the Effectiveness of Perioperative Antibiotics for Reduction of Burn Wound Bacterial Concentration Following Grafting Cefazolin, Clindamycin - Burn, Surgery | Phase 4 | Completed | Medstar Health Research Institute | 32 | 2018-05-29 | 2022-08-26 |
| Preoperative Antibiotics for Carpal Tunnel Release Surgery Vancomycin, Cefazolin, Saline Solution - Carpal Tunnel Syndrome | Phase 4 | Completed | WellSpan Health | 184 | 2018-05-17 | 2021-11-10 |
| Prevention of Infections in Cardiac Surgery (PICS) Prevena Study Prevena, Cefazolin, Vancomycin - Surgical Site Infections | Phase 4 | Completed | Population Health Research Institute | 4107 | 2018-03-05 | 2025-02-28 |
| 24 Vs 48 Hours of Cefazolin or Cefuroxime as Prophylaxis Cefuroxime, Cefazolin, 24 hours - Surgical Site Infection | Phase 4 | Completed | Saud Al Babtain Cardiac Center | 568 | 2018-02-06 | 2023-04-11 |
| Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections Dalbavancin, Vancomycin - Bone Infection, Osteomyelitis | Phase 4 | Completed | Infectious Diseases Physicians, Inc. | 41 | 2018-01-25 | 2023-10-03 |
| Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty- Multi-center Trial Cefazolin - Arthropathy of Knee, Antibiotic Prophylaxis | Phase 4 | Completed | Duke University | 1770 | 2017-10-24 | 2026-07-16 |
| Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS) Cefazolin, Clindamycin, Saline - Supracondylar Humerus Fracture, Post Operative Wound Infection | Phase 4 | Completed | Sumit Gupta | 160 | 2017-08-18 | 2024-08-09 |
| Adductor Canal Block With Periarticular Injection and IPACK (ACB/PAI/IPACK) Versus Periarticular Injection (PAI) Bupivacaine with epinephrine, Methylprednisolone, Cefazolin - Knee Arthropathy | Phase 4 | Completed | Hospital for Special Surgery, New York | 86 | 2017-02-28 | 2024-12-27 |
| The Efficacy of Prolonged Antibiotic Therapy for the Prevention of Relapsing Peritonitis in Peritoneal Dialysis Patients With High Dialysis Effluent Bacterial DNA Fragment Levels Extended antibiotics (cefazolin or ceftazidime), Usual antibiotics (cefazolin or ceftazidime) - Peritoneal Dialysis | Phase 4 | Completed | Chinese University of Hong Kong | 358 | 2016-02-26 | 2019-11-13 |
| Comparing Cefepime Versus Cefazolin Plus Ceftazidime for CAPD-associated Peritonitis Cefepime, Cefazolin plus Ceftazidime - Peritoneal Dialysis Associated Peritonitis | Phase 4 | Completed | Chulalongkorn University | 154 | 2015-08-01 | 2017-10-31 |
| Efficacy and Safety of Prophylactic Use of an Antibiotic for Medical Thoracoscopy Cefazolin, saline - Pleural Effusion, Pleurisy | Phase 4 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 100 | 2015-01-01 | 2017-01-18 |
| The Combination of Adductor Canal Block and Periarticular Injection. A Novel Technique for Patients Undergoing Total Knee Replacement (ACB PAI) Bupivacaine, Morphine, Methylprednisolone - Osteoarthritis | Phase 4 | Completed | Hospital for Special Surgery, New York | 111 | 2014-11-01 | 2019-01-11 |
| Wound Infections Following Implant Removal Cephalozin, Sodium chloride - Surgical Wound Infection | Phase 4 | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 500 | 2014-11-01 | 2016-12-22 |
| Antibiotic Prophylaxis for Revision, Clean Head and Neck Surgery Cefazolin, Placebo - Surgical Wound Infection | Phase 4 | Completed | Rabin Medical Center | 53 | 2014-01-01 | 2018-02-08 |
| Increased Cefazolin During Cesarean Delivery in Obese Population Cefazolin - Obesity, Obesity, Morbid | Phase 4 | Completed | MemorialCare Health System | 30 | 2013-08-01 | 2021-02-02 |
| Prevention of Arrhythmia Device Infection Trial (PADIT) Incremental, Conventional - Arrhythmia | Phase 4 | Completed | Population Health Research Institute | 12814 | 2012-12-01 | 2019-06-24 |
| Tissue and Plasma Pharmacokinetics of Cefazolin in Antibiotic Prophylaxis in Bariatric Surgery Cefazoline - Bariatric Surgery | Phase 4 | Completed | Nantes University Hospital | 117 | 2012-03-01 | 2017-07-19 |
| Pre-operative Prophylaxis With Vancomycin and Cefazolin in Pediatric Cardiovascular Surgery Patients Cefazolin 25 mg/kg body weight and Vancomycin hydrochloride, Cefazolin 30 mg/kg body weight - Congenital Heart Diseases, Aortic Valve Disorder | Phase 4 | Completed | Stanford University | 32 | 2012-02-01 | 2018-05-16 |
Showing 20 of 27. Sign in to see all of them.
Surgical Wound Infection (6) · Infections (4) · Obesity (3) · Wound Infection (3) · Arrhythmias, Cardiac (2) · Aortic Valve Disease (1) · Arthritis, Infectious (1) · Bacterial Infections (1) · Burns (1) · Carpal Tunnel Syndrome (1) · Empyema (1) · Heart Defects, Congenital (1) · Hernia, Inguinal (1) · Obesity, Morbid (1) · Osteoarthritis (1)
Population Health Research Institute (3) · Hospital for Special Surgery, New York (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Aultman Health Foundation (1) · Chinese University of Hong Kong (1) · Chulalongkorn University (1) · Diskapi Teaching and Research Hospital (1) · Duke University (1) · Infectious Diseases Physicians, Inc. (1) · Medstar Health Research Institute (1) · MemorialCare Health System (1) · Michael Stitely (1) · Nantes University Hospital (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · Rabin Medical Center (1)
United States (14) · Canada (3) · Israel (2) · Turkey (Türkiye) (2) · Australia (1) · France (1) · Greece (1) · Hong Kong (1) · India (1) · Italy (1) · Lebanon (1) · Malaysia (1) · Netherlands (1) · Saudi Arabia (1) · Singapore (1)
Andrew Krahn, MD (1) · Bahattin Bayar, MD (1) · Brett T Phillips, MD (1) · Craig Della Valle, MD (1) · David H Kim, MD (1) · David Lye, MBBS (1) · Deborah A Wing, MD (1) · Dominik Mertz, MD,MSc (1) · Donald Poretz, MD (1) · Dr. Andrew Krahn, M.D (1) · Duc T Bui, MD (1) · Duray Seker, MD (1) · Enrique A Goytizolo, MD (1) · Gaye E Seker, MD (1) · Hakan Kulacoglu, Professor (1)
PMID 19376733, PMID 21412147, PMID 22083832, PMID 27106640, PMID 29279933, PMID 29793587, PMID 30027615, PMID 30234517, PMID 30995208, PMID 31331757, PMID 34499720, PMID 38422496