48 completed, 21 recruiting, 15 unknown, 8 withdrawn. 54 Phase 2, 22 Phase 1, 13 Phase 3, 10 Early Phase 1, 7 Not applicable.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Epidiolex Trial for Presymptomatic Treatment of Sturge-Weber Syndrome Epidiolex 100 mg/mL Oral Solution - Sturge - Weber Syndrome (SWS) | Phase 2 | Recruiting | Johns Hopkins University | 10 | 2026-09-17 | 2026-10-02 |
| Evaluation of Oral THC and CBD in Men and Women Placebo, THC, CBD - Drug Abuse, Intoxication by Drug | Phase 1 | Recruiting | University of California, Los Angeles | 22 | 2026-08-13 | 2026-09-08 |
| Cannabidiol for Pain Relief of Patients With End-stage mCRPC Cannabidiol, Placebo - Metastatic Castration Resistant Prostate Cancer (mCRPC) | Phase 2 | Recruiting | Regionshospital Nordjylland | 58 | 2026-06-12 | 2026-09-16 |
| Challenging the Endocannabinoid System in Sleep Restricted Healthy Volunteers to Modulate Physiological Arousal (CANISLEEP) Study THC, CBD, THC + CBD - Healthy Volunteer | Not applicable | Recruiting | King's College London | 60 | 2026-06-02 | 2026-06-18 |
| The Pharmacokinetics of a Hemp-Based Topical Product CBD, THC - Cannabis | Phase 1 | Recruiting | Johns Hopkins University | 20 | 2026-05-26 | 2026-09-03 |
| CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury CBD - Supra-sacral Spinal Cord Injury, Spinal Cord Injury | Phase 2 | Recruiting | University of Wisconsin, Madison | 20 | 2026-02-13 | 2026-09-16 |
| Cannabinoids for Osteoarthritis Pain Effectiveness Trial CBD, THC, Placebo - Osteoarthritis of Knee, Osteoarthritis Hip | Not applicable | Recruiting | University Health Network, Toronto | 100 | 2026-01-29 | 2026-07-16 |
| Cannabis (THC vs. CBD) in Multiple Sclerosis THC, CBD - Multiple Sclerosis | Phase 2 | Recruiting | University of Calgary | 30 | 2025-12-05 | 2026-09-15 |
| Study of Cannabidiol and Neuroimaging on Stress Cannabidiol, Placebo - Early Life Adversity, Trauma | Phase 1 / Phase 2 | Recruiting | Icahn School of Medicine at Mount Sinai | 160 | 2025-10-29 | 2026-09-10 |
| Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors Biospecimen Collection, Cannabidiol, Dronabinol - Breast Carcinoma, Chemotherapy-Induced Peripheral Neuropathy | Phase 2 | Recruiting | City of Hope Medical Center | 120 | 2025-10-03 | 2025-12-05 |
| Warrior CARE: Cannabis Behavioral Health Tetrahydrocannabinol, Cannabidiol, Placebo - Post Traumatic Stress Disorder, Cannabis Use | Phase 1 / Phase 2 | Recruiting | Wayne State University | 500 | 2025-09-22 | 2026-08-07 |
| Adjunctive Cannabidiol for Recovery From Opioid Study Cannabidiol, Placebo - Opioid Use Disorder (OUD) | Phase 3 | Recruiting | Icahn School of Medicine at Mount Sinai | 450 | 2025-06-13 | 2026-10-01 |
| Clinical Trial with Cannabidiol (Kanbis®) for Parkinson Disease Symptoms Cannabidiol 100 mg/ml, cannabidiol 300 mg/ml, Cannabidiol 400 mg/ml - Parkinson Disease | Phase 2 | Recruiting | Laboratorio Elea Phoenix S.A. | 88 | 2024-11-28 | 2024-12-05 |
| High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breast Cancer Biospecimen Collection, BRC-001, Placebo Administration - Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | Phase 2 | Suspended | City of Hope Medical Center | 36 | 2024-08-26 | 2026-07-14 |
| Phytocannabinoids for the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors Cannabidiol, Delta-8-Tetrahydrocannabinol, Placebo Administration - Breast Carcinoma, Chemotherapy-Induced Peripheral Neuropathy | Early Phase 1 | Withdrawn | City of Hope Medical Center | 2024-07-06 | 2024-08-09 | |
| PAIN: A Project Assessing the Impact of a Novel Cannabinoid Product Cannabidiol, Placebo - Chronic Pain | Phase 2 | Active not recruiting | Staci Gruber, Ph.D. | 25 | 2024-06-27 | 2026-09-30 |
| Effects of a Hemp Product on the Pharmacokinetics and Pharmacodynamics of Clopidogrel Cannabidiol in the form of hemp, Clopidogrel - Interaction | Early Phase 1 | Recruiting | Washington State University | 24 | 2024-06-20 | 2026-06-04 |
| Cannabidiol Effects on Fear Extinction in Social Phobia Fear extinction, Cannabidiol Cap/Tab, Placebo - Social Anxiety Disorder | Early Phase 1 | Unknown | Hartford Hospital | 20 | 2024-04-30 | 2024-04-19 |
| The CanISleepinMS Study: Effect of Cannabidiol (CBD) on Sleep Quality in Patients With Multiple Sclerosis Cannabidiol Oil - Sleep Quality, Multiple Sclerosis | Phase 2 | Completed | Wageningen University | 16 | 2024-03-26 | 2026-09-25 |
| CBD for Individuals at Risk for Alzheimer's Disease Cannabidiol, Placebo - Mild Cognitive Impairment | Phase 2 | Recruiting | University of Colorado, Denver | 236 | 2024-01-19 | 2026-06-15 |
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Marijuana Abuse (19) · Epilepsy (10) · Opioid-Related Disorders (7) · Anxiety Disorders (6) · Pain (6) · Chronic Pain (5) · Drug Resistant Epilepsy (4) · Seizures (4) · Stress Disorders, Post-Traumatic (4) · Alcoholism (2) · Alzheimer Disease (2) · Arthralgia (2) · Arthritis, Rheumatoid (2) · Autism Spectrum Disorder (2) · Brain Injuries, Traumatic (2)
Jazz Pharmaceuticals (12) · Johns Hopkins University (5) · University of Colorado, Denver (5) · City of Hope Medical Center (3) · University of California, Los Angeles (3) · Yale University (3) · Anne Comi, MD (2) · Calithera Biosciences, Inc (2) · Castleton University (2) · Centre hospitalier de l'Université de Montréal (CHUM) (2) · Hartford Hospital (2) · Hurd,Yasmin, Ph.D. (2) · Icahn School of Medicine at Mount Sinai (2) · King's College London (2) · NYU Langone Health (2)
United States (69) · Canada (8) · Spain (7) · United Kingdom (7) · Netherlands (6) · Australia (5) · Israel (4) · Poland (4) · Denmark (3) · Brazil (2) · Italy (2) · Sweden (2) · Argentina (1) · Jamaica (1) · Switzerland (1)
Anne M Comi, MD (2) · Debra Kimless, M.D. (2) · Joao De Aquino, M.D. (2) · Tory Spindle, PhD (2) · Yasmin Hurd, PhD (2) · Brent DeGeorge, MD, PhD (1) · Brian Martis, MD (1) · Catherine R Ayers, PhD (1) · Charles Marmar, MD (1) · David Tolin, Ph.D. (1) · Deborah Yurgelun-Todd, Ph.D. (1) · Debra Kelsh, MD (1) · Didier Jutras-Aswad, MD,MS (1) · Didier Jutras-Aswad, MD,MS,FRCPC (1) · Dr. Hance Clarke, MD (1)
PMID 29063814, PMID 31048098, PMID 34957550, PMID 27573936, PMID 31109198, PMID 32119035, PMID 32350749, PMID 32652616, PMID 33346789, PMID 33464660, PMID 34210360, PMID 34265088, PMID 34287833, PMID 34406656, PMID 34619044, PMID 35135986, PMID 35175622, PMID 35239547, PMID 36105269, PMID 36123113, PMID 38441854, PMID 38466972, PMID 38770686, PMID 39016024, PMID 39680411, PMID 39719161, PMID 40357520, PMID 41469488, PMID 41514385, PMID 42454450
2015 (6), 2014 (3), P30CA033572 (3), 2019 (2), 2018 (1), K23DA052682 (1), R01MH139940 (1), R21CA260447 (1), R21DA027781 (1), U54AT008909 (1), UH3DA050323 (1)