8 completed, 2 unknown, 1 terminated. 11 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Completed 8, Unknown 2, Terminated 1 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
Follow Brimonidine Tartrate: new trials by email Literature Review of Brimonidine Tartrate trials Research Report on Brimonidine Tartrate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety, Tolerability and Pharmacokinetics of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Chinese With Presbyopia LNZ101 (Aceclidine /Brimonidine) ophthalmic solution, LNZ100 (Aceclidine) ophthalmic solution, Placebo (Vehicle) ophthalmic solution - Presbyopia | Phase 1 | Completed | Corxel Pharmaceuticals | 21 | 2024-03-04 | 2024-04-23 |
| Plasma Pharmacokinetics and Safety of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Subjects With Presbyopia Aceclidine + Brimonidine, Aceclidine - Eye Diseases, Presbyopia | Phase 1 | Completed | LENZ Therapeutics, Inc | 30 | 2023-07-06 | 2023-10-16 |
| Pilocarpine, Brimonidine, Oxymetazoline (PBO) Compound to Control Presbyopia Symptoms Pilocarpine, brimonidine, oxymetazoline, hyaluronic acid, bromfenac (PBOHB) compound - Presbyopia | Phase 1 | Unknown | Optall Vision | 11 | 2021-08-14 | 2021-08-17 |
| Comparison of a Compound With Pilocarpine and Brimonidine to Improve Near Vision in Healthy Presbyopic Patients Compound Pilocarpine, Brimonidine, Oxymetazoline, Hyaluronic acid, Bromfenac, Pilocarpine Hydrochloride, Brimonidine Tartrate - Presbyopia | Phase 1 | Unknown | Optall Vision | 11 | 2021-08-10 | 2021-08-19 |
| Compound to Control Presbyopia Symptoms PBO to control presbyopia symptoms - Presbyopia | Phase 1 | Completed | Optall Vision | 11 | 2020-06-01 | 2021-08-19 |
| KJ-TFC-004 Drug-drug Interaction Study [A], [B], [A]+[B](1) - Glaucoma, Eye Diseases | Phase 1 | Completed | Kukje Pharma | 32 | 2016-12-01 | 2018-04-11 |
| The Effect of Brimonidine on Intraocular Pressure When Dilating Routine Patients Alphagan, Phenylephrine, Tropicamide - Intraocular Pressure | Phase 1 | Completed | Wake Forest University Health Sciences | 5 | 2016-09-01 | 2018-08-09 |
| Brimonidine Eye Drops for Treatment of Ocular Graft-vs-Host Disease (oGVHD) Brimonidine 0.15%, Brimonidine 0.075%, Placebo - Dry Eye, Ocular Graft vs Host Disease | Phase 1 / Phase 2 | Terminated | Sandeep Jain, MD | 15 | 2016-05-01 | 2019-11-08 |
| Pharmacokinetics and Safety of Topical Administration of Brimonidine Tartrate Ophthalmic Solution 0.025%. Brimonidine tartrate - Hyperemia | Phase 1 | Completed | Bausch & Lomb Incorporated | 12 | 2014-02-01 | 2017-04-28 |
| Pharmacokinetics of the Brimonidine Tartrate Posterior Segment Delivery System in Patients Undergoing Pars Plana Vitrectomy 400 µg Brimonidine Tartrate Implant, 200 µg Brimonidine Tartrate Implant - Vitrectomy | Phase 1 | Completed | Allergan | 24 | 2010-12-01 | 2013-08-05 |
| An Exploratory Study to Evaluate the Safety of Brimonidine Intravitreal Implant in Patients With Retinitis Pigmentosa 400 µg Brimonidine Tartrate Implant, 200 µg Brimonidine Tartrate Implant, 100 µg Brimonidine Tartrate Implant - Retinitis Pigmentosa | Phase 1 / Phase 2 | Completed | Allergan | 21 | 2008-07-01 | 2013-04-24 |
Presbyopia (5) · Eye Diseases (2) · Dry Eye Syndromes (1) · Glaucoma (1) · Hyperemia (1) · Meibomian Gland Dysfunction (1) · Mydriasis (1) · Ocular Hypertension (1) · Refractive Errors (1) · Retinitis Pigmentosa (1)
Optall Vision (3) · Allergan (2) · Bausch & Lomb Incorporated (1) · Corxel Pharmaceuticals (1) · Kukje Pharma (1) · LENZ Therapeutics, Inc (1) · Sandeep Jain, MD (1) · Wake Forest University Health Sciences (1)
United States (6) · Mexico (3) · China (1) · Czechia (1) · France (1) · Germany (1) · Portugal (1) · South Korea (1)
Cesar Alejandro S Galeana, MD (2) · Cesar Alejandro S Galeana (1) · Joseph Ciolino, MD (1) · Keith Walter, MD (1) · Kris Gameblin (1) · Kyung-sang Yu, Ph.d., M.B.A (1) · Larry Li, Doctor (1) · Sandeep Jain, MD (1)