7 completed, 5 recruiting, 3 unknown, 1 not yet recruiting. 14 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Recruiting 5, Completed 4, Unknown 3, Not yet recruiting 1, Terminated 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Brain-computer interface: new trials by email Literature Review of Brain-computer interface trials Research Report on Brain-computer interface
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT) INTENT Neural Interface System - Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS) | Not applicable | Recruiting | Johns Hopkins University | 5 | 2027-01-01 | 2026-10-09 |
| BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Aphasia BrainGate Neural Interface System - Expressive Aphasia, Aphasia Following Cerebral Infarction | Not applicable | Not yet recruiting | Leigh R. Hochberg, MD, PhD. | 5 | 2026-11-01 | 2026-10-22 |
| fNIRS-BCI Neurofeedback in Stroke Rehabilitation Brain-computer interface, Sham brain-computer interface - Stroke | Not applicable | Recruiting | The Hong Kong Polytechnic University | 44 | 2024-12-12 | 2025-08-22 |
| Efficacy of a Brain-Computer Interface Controlled Functional Electrical Stimulation Therapy for Spinal Cord Injury Neurorehabilitation Brain-Computer Interface, Sham Brain-Computer Interface - Cervical Spinal Cord Injury | Not applicable | Recruiting | Instituto Nacional de Rehabilitacion | 32 | 2022-08-01 | 2025-06-25 |
| EEG Brain-Machine Interface Control of an Upper-Limb Robotic Exoskeleton for Robot-Assisted Rehabilitation After Stroke NeuroExo co-robot neurorehabilitation system - Stroke, Hemiparesis | Not applicable | Unknown | University of Houston | 30 | 2022-04-25 | 2022-05-16 |
| Validation of a Brain-Computer Interface for Stroke Neurological Upper Limb Rehabilitation Brain-Computer Interface, Sham Brain-Computer Interface - Stroke, Ischemic, Stroke | Not applicable | Completed | Instituto Nacional de Rehabilitacion | 23 | 2021-03-16 | 2024-07-12 |
| An Online Home-based Intervention for Anxiety Regulation Brain-Computer Interface - Anxiety | Not applicable | Unknown | Duke-NUS Graduate Medical School | 30 | 2021-01-05 | 2021-11-17 |
| The Effectiveness of Rehabilitation Training Based on Brain-computer Interface Technology to Improve the Upper Limb Motor Function of Ischemic Stroke. Brain-computer interface, Traditional rehabilitation - Hemiplegia Following Ischemic Stroke | Not applicable | Completed | Beijing Tiantan Hospital | 300 | 2020-05-10 | 2024-02-21 |
| NeuroCognitive Communicator: Safety Study NeuroCognitive Communicator - Motor Neuron Disease, Amyotrophic Lateral Sclerosis, Tetraplegia | Not applicable | Unknown | Ottawa Hospital Research Institute | 2 | 2019-05-13 | 2022-08-01 |
| BCI and Evaluation of Visual and Task Performance in Subjects With Eye Diseases Visual Performance tests, Brain-computer interface - Glaucoma, Macular Degeneration | Not applicable | Completed | University of Miami | 115 | 2018-10-29 | 2024-11-26 |
| Brain-Computer Interface System for Training Memory and Attention in Elderly Brain-Computer Interface - Alzheimer's Disease, Mild Cognitive Impairment | Phase 2 | Completed | Duke-NUS Graduate Medical School | 240 | 2015-07-01 | 2017-08-02 |
| Cortical Recording and Stimulating Array Brain-Machine Interface Implantation of CRS Arrays - Tetraplegia, Spinal Cord Injury | Not applicable | Recruiting | Michael Boninger | 30 | 2013-12-01 | 2026-05-20 |
| Effectiveness of a Brain-Computer Interface Based System for Cognitive Enhancement in the Normal Elderly BrainPalTM - Alzheimer's Disease, Mild Cognitive Impairment | Phase 1 | Completed | Duke-NUS Graduate Medical School | 82 | 2012-04-01 | 2014-07-25 |
| Microelectrode Brain-Machine Interface for Individuals With Tetraplegia Implantation of NeuroPort Arrays in the motor cortex - Tetraplegia, Spinal Cord Injury | Not applicable | Terminated | Michael Boninger | 1 | 2011-05-01 | 2024-01-09 |
| ECoG Direct Brain Interface for Individuals With Upper Limb Paralysis Implantation of ECoG sensors on the brain surface - Tetraplegia, Spinal Cord Injury | Not applicable | Completed | University of Pittsburgh | 6 | 2011-05-01 | 2016-12-12 |
| Brain-Computer Interface (BCI) Based Intervention for Attention Deficit Hyperactivity Disorder (ADHD) BCI - Attention Deficit Hyperactivity Disorder | Phase 2 / Phase 3 | Completed | National Healthcare Group, Singapore | 192 | 2011-01-01 | 2017-03-30 |
| BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia Placement of the BrainGate2 sensor(s) into the motor-related cortex - Tetraplegia, Spinal Cord Injuries | Not applicable | Recruiting | Leigh R. Hochberg, MD, PhD. | 27 | 2009-05-01 | 2026-06-01 |
Quadriplegia (7) · Spinal Cord Injuries (5) · Brain Stem Infarctions (4) · Amyotrophic Lateral Sclerosis (3) · Muscular Dystrophies (3) · Stroke (3) · Alzheimer Disease (2) · Cognitive Dysfunction (2) · Dementia (2) · Paresis (2) · Anxiety Disorders (1) · Aphasia (1) · Aphasia, Broca (1) · Attention Deficit Disorder with Hyperactivity (1) · Glaucoma (1)
Duke-NUS Graduate Medical School (3) · Instituto Nacional de Rehabilitacion (2) · Leigh R. Hochberg, MD, PhD. (2) · Michael Boninger (2) · Beijing Tiantan Hospital (1) · Johns Hopkins University (1) · National Healthcare Group, Singapore (1) · Ottawa Hospital Research Institute (1) · The Hong Kong Polytechnic University (1) · University of Houston (1) · University of Miami (1) · University of Pittsburgh (1)
United States (7) · Singapore (4) · Mexico (2) · Canada (1) · China (1) · Hong Kong (1)
Jessica Cantillo-Negrete, PhD (2) · Michael L Boninger, MD (2) · Tih Shih Lee, MD, PhD (2) · Choon Guan Lim (1) · Felipe A Medeiros, MD, PhD (1) · Gerard Francisco, MD (1) · Henry Tseng, MD, PhD (1) · Jennifer L Collinger, PhD (1) · Jose L Contreras-Vidal, PhD (1) · Leigh R Hochberg, M.D., Ph.D. (1) · Leigh R Hochberg, MD, PhD (1) · Nathan Crone, MD (1) · Tih Shih Lee, MD PHD (1)
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R01DC009899 (1), R01DC014034 (1), R01EY029885 (1), U01DC017844 (1), U01NS123101 (1), UH2NS095548 (1)