39 completed, 11 unknown, 10 terminated, 7 withdrawn. 74 Phase 2, 14 Phase 3, 12 Phase 1.
Follow Botox: new trials by email Literature Review of Botox trials Research Report on Botox
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neoadjuvant Intraprostatic OnabotulinumtoxinA Before Radical Prostatectomy for High-Risk Localized Prostate Cancer OnabotulinumtoxinA (BOTOX®), Normal Saline Placebo - Prostate Cancer | Phase 1 / Phase 2 | Not yet recruiting | The Methodist Hospital Research Institute | 30 | 2026-11-01 | 2026-09-02 |
| MRI Study of OnabotulinumtoxinA (OnabotA) Effect on Jaw Muscle Pain Onabotulinumtoxin A, Placebo - Masticatory Myofascial Pain Syndrome | Phase 2 | Not yet recruiting | Weill Medical College of Cornell University | 120 | 2026-10-01 | 2026-10-16 |
| Cleft Lip Scarring After Botox Botulinum Toxin Type A (BOTOX) Injection, Normal Saline - Cleft Lip, Cleft Lip Scar | Phase 2 | Recruiting | Children's National Research Institute | 40 | 2026-02-19 | 2026-10-19 |
| Botulinum Toxin A Before Hemorrhoidectomy to Prevent Postoperative Pain Botulinum toxin type A, Saline (0.9% NaCl) - Hemorrhoids, Postoperative Pain | Phase 2 | Recruiting | Lomonosov Moscow State University Medical Research and Educational Center | 292 | 2026-02-01 | 2026-03-10 |
| Serratus Plane Block (SPB) Versus Capsaïcine Versus Botox-A for Chronic Neuropathic Pain in Post-mastectomy Syndrome Capsaicin 8% Patch, Serratus Plane Block, Botulinum Toxin A - Post-Mastectomy Neuropathic Pain Syndrome | Phase 2 | Withdrawn | Centre Oscar Lambret | 2025-06-10 | 2026-10-06 | |
| Female Sexual Dysfunction Assessment and Managment of Vaginismus Botox, Radiofrequency - Female Sexual Dysfunction | Phase 2 / Phase 3 | Not yet recruiting | Assiut University | 40 | 2025-01-01 | 2025-01-01 |
| Evaluation of Efficacy of Botulinum Toxin A Plus Oral Tadalafil 5 mg in Diabetic Men With Erectile Dysfunction Botulinum toxin A, Tadalafil 5mg - Erectile Dysfunction With Diabetes Mellitus | Phase 2 / Phase 3 | Recruiting | Aswan University Hospital | 32 | 2024-08-01 | 2024-12-03 |
| A Study to Evaluate Safety and Efficacy of BOTOX in Adults With Moderate COPD OnabotulinumtoxinA, Placebo - COPD | Phase 2 | Completed | RMW Testing | 40 | 2023-10-01 | 2024-07-17 |
| Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms OnabotulinumtoxinA - Urinary Incontinence, Overactive Bladder Syndrome | Phase 2 / Phase 3 | Active not recruiting | Northwestern University | 66 | 2023-07-13 | 2026-11-06 |
| Endoscopic Botulinum Toxin Injection in the Prevention of Postoperative Pancreatic Fistula Following Distal Pancreatectomy Botulinum Toxin Type A - Pancreatic Carcinoma | Phase 2 | Terminated | OHSU Knight Cancer Institute | 4 | 2023-03-01 | 2025-05-13 |
| Treatment of Frostbite Sequelae With Botulinum Toxin A Botuinum toxin - Cold Hypersensitivity, Vascular System Injuries | Phase 2 | Withdrawn | University Hospital of North Norway | 2022-11-01 | 2024-06-14 | |
| Study of BOTOX Injections to Assess Change in Disease Symptoms in Adult Participants With Upper Limb Essential Tremor BOTOX, Placebo for BOTOX - Upper Limb Essential Tremor (UL ET) | Phase 2 | Completed | AbbVie | 174 | 2022-04-12 | 2026-01-20 |
| Study of BOTOX Injections to Assess Change in Disease Activity and Adverse Events in Adult Female Participants With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) BOTOX, Placebo for BOTOX - Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) | Phase 2 | Completed | AbbVie | 83 | 2022-03-29 | 2025-05-06 |
| A Study of OnabotulinumtoxinA X Injection in Adult Participants With Glabellar Lines Formulation A: OnabotulinumtoxinA, Formulation B: OnabotulinumtoxinA, Formulation C: OnabotulinumtoxinA - Glabellar Lines | Phase 2 | Completed | Allergan | 92 | 2021-09-01 | 2025-06-27 |
| Efficacy and Safety of Low Energy Shock Wave Plus BotulinumToxin A in Treating Patients With Interstitial Cystitis BOTOX 100U in normal saline, Normal saline - Interstitial Cystitis | Phase 2 | Unknown | Buddhist Tzu Chi General Hospital | 75 | 2021-05-18 | 2022-03-25 |
| Investigating Effects of BOTOX on Weight Loss and Glucose Tolerance in Obese, Type 2 Diabetic Subjects Botox 200 UNT Injection - Obese, Diabetes Mellitus, Type 2 | Phase 1 / Phase 2 | Terminated | Vanderbilt University Medical Center | 4 | 2021-04-29 | 2023-02-28 |
| Masseter Myofascial Pain Relief Following an Intra-muscular Injection With Botulinum Toxin Type A. Botulinum toxin type A, saline solution - Myalgia, Myofascial Pain | Phase 2 | Unknown | Region Örebro County | 48 | 2020-07-01 | 2020-06-11 |
| Botox for the Treatment of Chronic Exertional Compartment Syndrome OnabotulinumtoxinA Injection - Compartment Syndrome of Leg | Phase 1 / Phase 2 | Terminated | University of Wisconsin, Madison | 7 | 2019-10-08 | 2023-02-14 |
| Intraoral Administration of Botox in Patients With Dentoalveolar Neuropathic Pain onabotulinum toxin A - Neuropathic Pain | Phase 2 | Completed | Isabel Moreno Hay | 8 | 2019-09-11 | 2026-07-30 |
| Botulinum Toxin A & Weekly Serial Casting in ABI Inpatients With Lower Extremity Spasticity Botulinum toxin type A, Serial Casting - Spastic Foot | Phase 2 | Withdrawn | Hamilton Health Sciences Corporation | 2019-09-01 | 2023-09-28 |
Showing 20 of 74. Sign in to see all of them.
Urinary Bladder, Overactive (6) · Pain (5) · Cystitis, Interstitial (4) · Migraine Disorders (4) · Neuralgia (3) · Urinary Incontinence (3) · Agnosia (2) · Breast Neoplasms (2) · Cerebral Palsy (2) · Cluster Headache (2) · Headache Disorders (2) · Lacerations (2) · Pain, Postoperative (2) · Prostatic Hyperplasia (2) · Prostatic Neoplasms (2)
Norwegian University of Science and Technology (7) · Buddhist Tzu Chi General Hospital (3) · AbbVie (2) · Daewoong Pharmaceutical Co. LTD. (2) · Mayo Clinic (2) · St. Olavs Hospital (2) · Yale University (2) · Allergan (1) · Assiut University (1) · Aswan University Hospital (1) · Benjamin Sucher (1) · Catholic University of the Sacred Heart (1) · Centre Oscar Lambret (1) · Children's National Research Institute (1) · DeNova Research (1)
United States (36) · Norway (11) · Canada (4) · Taiwan (3) · Egypt (2) · France (2) · Germany (2) · South Korea (2) · Thailand (2) · China (1) · Israel (1) · Italy (1) · Japan (1) · Russia (1) · Spain (1)
Erling A Tronvik, PhD, MD (2) · Hann-Chorng Kuo, M.D. (2) · Ami Sidi, Prof MD (1) · Amy Krambeck, MD (1) · Anand D Pandyan, PhD (1) · Angelo E Gousse, MD (1) · Arne J Norheim, PhD (1) · Bahman Jabbari, M.D. (1) · Benjamin Sucher, DO (1) · Brett C Sheppard, M.D., FACS (1) · Brian Miles, MD (1) · Christopher P Smith, MD (1)
PMID 11743295, PMID 12893330, PMID 12907905, PMID 15126771, PMID 15291863, PMID 16400513, PMID 18461049, PMID 18844269, PMID 19194764, PMID 19648387, PMID 19734516, PMID 19811515, PMID 20627413, PMID 20810509, PMID 21791356, PMID 21868066, PMID 22071153, PMID 22370242, PMID 22747635, PMID 23370086, PMID 26232105, PMID 26394198, PMID 26808752, PMID 27154997, PMID 28367260, PMID 28452678, PMID 28509693, PMID 29037377, PMID 29331031, PMID 31342515, PMID 32583902, PMID 32734597, PMID 33040610, PMID 33106278, PMID 33134600, PMID 35102782, PMID 35166150, PMID 36048469, PMID 36325678, PMID 36357803, PMID 36619264, PMID 37435807, PMID 40192825, PMID 8501266
2017 (2), 2014 (1), 2015 (1), 2016 (1), R33AT012270 (1)