18 completed, 3 terminated, 1 withdrawn. 11 Not applicable, 3 Phase 1, 3 Phase 2, 3 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 8, Terminated 2, Withdrawn 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Phase 4 | 3 | Completed 3 |
| Phase 3 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Controlled Study on Pain Management With Injection of Botulinum Toxin for Glabellar Line Correction Vibrating Beauty Bar - Injection Site Discomfort | Phase 4 | Completed | Galderma R&D | 60 | 2023-10-23 | 2024-03-22 |
| Ethnic Lip Augmentation With Hyaluronic Acid Filler Volbella or Juvederm Ultra XC filler - Lip Augmentation, Lip Fullness | Phase 3 | Completed | DeNova Research | 20 | 2022-11-01 | 2023-09-07 |
| First Impressions and Attractiveness Levels of Smiling Individuals With and Without a Mask First Impressions, Attractiveness | Completed | DeNova Research | 808 | 2022-03-04 | 2022-04-25 | |
| ZOOM First Impressions Attractiveness, Self-Esteem, Trustworthiness - Attractiveness, Self Esteem | Not applicable | Withdrawn | DeNova Research | 2021-11-01 | 2023-02-22 | |
| Non-Surgical Rhinoplasty Using PDO Threads PDO max threads - Nasal Defect | Not applicable | Completed | DeNova Research | 10 | 2021-01-20 | 2021-10-12 |
| Effects of Mitigation Treatments on Bruising of CCH-aaes Treatment of Buttock Cellulite CCH-aaes, Compression, Cold Packs - Edematous Fibrosclerotic Panniculopathy (EFP), Cellulite | Phase 4 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 48 | 2020-12-28 | 2023-08-21 |
| Impact of Botox Treatment Into the Upper One Third of the Face an Area on Mood and Self -Appearance Satisfaction Botulinum Neurotoxin, Placebo - Mood | Phase 1 | Completed | DeNova Research | 45 | 2020-07-20 | 2021-03-15 |
| Restylane® Lyft Filler Injection for Hand Rejuvenation on First Impressions Restylane® Lyft - Hand Rejuvination | Phase 1 | Completed | DeNova Research | 10 | 2019-10-10 | 2019-11-19 |
| Effects of Restylane-L® Filler Injection for Non-Surgical Rhinoplasty Restylane-L® Filler injection - Deformity of Nasal Cartilage | Phase 1 | Completed | DeNova Research | 10 | 2019-01-01 | 2020-08-13 |
| Oral Nutraceutical Supplement With Standardized Botanicals in Males With Self-Perceived Thinning Hair and Loss Oral Nutraceutical Supplement, Placebo - Hair Loss, Hair Thinning | Not applicable | Terminated | DeNova Research | 74 | 2018-10-15 | 2023-05-16 |
| Perioral Rejuvenation and Upper Lip Enhancement Restylane® Defyne - Perioral Rejuvenation, Upper Lip Projection | Not applicable | Completed | DeNova Research | 20 | 2017-11-20 | 2020-10-08 |
| A Study to Examine the Effects of Cosmeceutical Therapy in Subjects Undergoing Full Facial Rejuvenation Basic Skin Care, Active Skin Care - Facial Rejuvenation With Neurotoxins and/or Hyaluronic Acid Fillers | Not applicable | Completed | DeNova Research | 20 | 2016-03-01 | 2020-10-14 |
| A Study to Assess the Efficacy of Skin Rejuvenation Therapy in Combination With Neurotoxin and Full Facial Filler Treatments NuDerm® System, Placebo - Subjects Requesting and Requiring Facial Rejuvenation With Neurotoxins and/or Hyaluronic Acid Fillers | Not applicable | Completed | DeNova Research | 20 | 2015-10-06 | 2019-02-08 |
| Assess the Impact of Lip Rejuvenation on Projected First Impressions and Mood Perceptions Restylane® Silk - Lip Rejuvenation | Not applicable | Completed | DeNova Research | 20 | 2015-09-01 | 2020-11-04 |
| A Study of Nutritional Supplementation in Altering Ecchymosis, Erythema and Health Outcomes Associated With Aesthetic Procedures Multizyme Cellular Vitality Cyruta Plus SHEP - Ecchymosis and Erythema Commonly Associated With Soft Tissue Filler Injections | Not applicable | Completed | DeNova Research | 108 | 2013-07-01 | 2018-06-01 |
| Efficacy of the New Viviscal Professional Strength Oral Supplement in Females With Thinning Hair New Viviscal Professional Supplement, Placebo tablets - Hair Thinning | Not applicable | Completed | Ablon Skin Institute Research Center | 40 | 2013-02-01 | 2014-11-26 |
| A Study Evaluating the Efficacy and Safety of ARTISS Human Fibrin Sealant as Used in External Rhinoplasty ARTISS human fibrin sealant - Subjects Requesting and Requiring an Open Rhinoplasty | Phase 2 | Completed | DeNova Research | 10 | 2012-11-28 | 2020-11-02 |
| A Double-Blinded, Randomized Placebo Controlled Pilot Study Comparing the Efficacy and Safety of IncobotulinumtoxinA Versus Saline Injections to the Cheek Region in Patients With Rosacea IncobotulinumtoxinA, Bacteriostatic saline - Rosacea | Phase 2 | Completed | DeNova Research | 9 | 2012-06-01 | 2020-10-08 |
| Safety and Efficacy Study of Polydioxanone (PDS) Plates in Rhinoplasty Polydioxanone (PDS) plates, Caudal septal extension graft performed through endonasal rhinoplasty - Rhinoplasty | Not applicable | Completed | DeNova Research | 30 | 2010-11-24 | 2020-11-04 |
| Botulinum Toxin A for Herpes Labialis onabotulinumtoxinA, Bacteriostatic normal saline - Herpes Labialis | Not applicable | Terminated | DeNova Research | 20 | 2010-08-01 | 2020-12-21 |
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Alopecia (2) · Acne Vulgaris (1) · Cellulite (1) · Ecchymosis (1) · Herpes Labialis (1) · Rosacea (1) · Smiling (1)
Botulinum Toxins, Type A (2) · Bone Plates (1) · Botulinum Toxins (1) · Durapatite (1) · Prolaryn Plus (1) · Sodium Chloride (1) · Vascularin-Gel (1) · incobotulinumtoxinA (1)
United States (21)
Steven H Dayan, MD (9) · Steven Dayan, MD (2) · Glynis Ablon, MD, FAAD (1) · Steven Dayan, MD, FACS (1) · Steven H Dayan, MD F.A.C.S. (1) · Steven H Dayan, MD FACS (1)
PMID 25805282, PMID 26044342, PMID 26441107, PMID 26501937, PMID 30059389