7 completed, 3 recruiting, 3 unknown, 2 not yet recruiting. 15 Not applicable, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Completed 7, Recruiting 3, Not yet recruiting 2, Unknown 2, Active not recruiting 1 |
| Early Phase 1 | 1 | Unknown 1 |
Follow Auricular vagus nerve stimulation: new trials by email Literature Review of Auricular vagus nerve stimulation trials Research Report on Auricular vagus nerve stimulation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Noninvasive CA Monitoring Validation and Autonomic Modulation in Aneurysmal Subarachnoid Hemorrhage Right-Sided Cervical Sympathetic Block at C6, Transcutaneous Auricular Vagal Nerve Stimulation (taVNS) - Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia | Not applicable | Not yet recruiting | University of Texas Southwestern Medical Center | 300 | 2027-07-01 | 2026-10-16 |
| SENECA - Smart Therapies for Chronic Pain VIVO 2nd GEN, Standard-of-Care Multimodal Pain Therapy - Chronic Low Back Pain (CLBP) | Not applicable | Not yet recruiting | Aurimod GmbH | 44 | 2026-09-17 | 2026-08-31 |
| Effects of Transcutaneous Vagus Nerve Stimulation in Older Adults Active location tVNS, Sham Comparator - Older Adults Without Any Specific Clinical Condition, Autonomic Nervous System Imbalance | Not applicable | Completed | Universidade da Coruña | 12 | 2025-12-19 | 2026-03-02 |
| Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery Auricular vagus nerve stimulation, Sham Auricular Vagus nerve Stimulation - Spinal Fusion, Hyperglycemia | Not applicable | Recruiting | Alexander T. Yahanda | 50 | 2025-10-08 | 2026-08-18 |
| Transcutaneous Auricular Vagus Enhanced Recovery in the NeuroICU Auricular Vagus Nerve Stimulation, Sham Auricular Vagus nerve Stimulation - Acute Neurological Injury, Acute Medical Conditions | Not applicable | Recruiting | Washington University School of Medicine | 160 | 2025-09-24 | 2026-10-07 |
| Auricular VNS Following Intracerebral Hemorrhage Auricular Vagus Nerve Stimulation, Sham Auricular Vagus nerve Stimulation - Intracerebral Hemorrhage | Not applicable | Recruiting | Washington University School of Medicine | 80 | 2025-04-06 | 2026-07-06 |
| tAVNS for Stress Reduction in University Students taVNS, Sham - Psychological Distress, Stress (Psychology) | Not applicable | Completed | Egas Moniz - Cooperativa de Ensino Superior, CRL | 40 | 2025-01-10 | 2026-04-08 |
| Compare the Effects of Different AVNS Parameters on Neck Pain, HRV, Balance in Collegiate Atheletes Auricular vagus nerve stimulation - Neck Pain, Heart Rate Variability | Not applicable | Unknown | University of Sharjah | 70 | 2024-05-29 | 2024-06-13 |
| Research on the Heart-Brain Coupling Mechanisms and Interventions for Emotional Inhibitory Control Deficits in Individuals With Alcohol Use Disorder Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Sham Stimulation, Mindfulness Training - Alcohol Use Disorder (AUD) | Not applicable | Completed | Shanghai Mental Health Center | 60 | 2024-03-15 | 2025-06-25 |
| Effect of Auricular Vagus Nerve Stimulation on Pain and Symptoms in Primary Dysmenorrhea Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Sham transcutaneous auricular vagus nerve stimulation - Primary Dysmenorrhea (PD), Primary Dysmenorrhea | Not applicable | Completed | Istanbul Gelisim University | 40 | 2023-06-01 | 2026-07-06 |
| Effect of Auricular Vagus Nerve Stimulation in Women With Migraine Disease Auricular Vagus Nerve Stimulation - Chronic Migraine, Headache | Not applicable | Completed | Bahçeşehir University | 60 | 2022-06-06 | 2023-02-28 |
| Impact of Transcutaneous Auricular Vagus Nerve Stimulation on Digestive Symptoms in Systemic Sclerosis Systemic Sclerosis Auricular vagus nerve stimulation, Sham Auricular vagus nerve stimulation - Systemic Sclerosis | Not applicable | Completed | University Hospital, Grenoble | 20 | 2021-11-09 | 2024-12-06 |
| The Effect of Vagus Nerve Stimulation on Sportive Performance. Auricular vagus nerve stimulation, Sham Auricular Vagus Nerve Stimulation (AVNS) - Sports Performance | Not applicable | Completed | İSMAİL CEYLAN | 60 | 2021-09-01 | 2022-06-29 |
| Comparison of Different Weight Loss Methods in Obese Individuals AURICULAR VAGUS NERVE STIMULATION, DIET, EXERCISE - Obesity | Not applicable | Unknown | Bahçeşehir University | 90 | 2021-07-01 | 2022-08-24 |
| Auricular VNS Following Subarachnoid Hemorrhage Auricular Vagus Nerve Stimulation, Sham Auricular Vagus nerve Stimulation - Subarachnoid Hemorrhage | Not applicable | Active not recruiting | Anna Huguenard | 50 | 2021-01-05 | 2026-10-27 |
| Auricular Concha Electro-acupuncture for the Treatment of Depression Auricular vagus nerve stimulation, Citalopram - Depression, Depressive Symptom | Early Phase 1 | Unknown | China Academy of Chinese Medical Sciences | 106 | 2018-09-17 | 2019-04-22 |
Brain Diseases (2) · Central Nervous System Diseases (2) · Depression (2) · Hemorrhage (2) · Nervous System Diseases (2) · Pathologic Processes (2) · Subarachnoid Hemorrhage (2) · Vascular Diseases (2) · Alcoholism (1) · Anxiety Disorders (1) · Autonomic Nervous System Diseases (1) · Cerebral Hemorrhage (1) · Cerebrovascular Disorders (1) · Chronic Pain (1) · Depressive Disorder (1)
Bahçeşehir University (2) · Washington University School of Medicine (2) · Alexander T. Yahanda (1) · Anna Huguenard (1) · Aurimod GmbH (1) · China Academy of Chinese Medical Sciences (1) · Egas Moniz - Cooperativa de Ensino Superior, CRL (1) · Istanbul Gelisim University (1) · Shanghai Mental Health Center (1) · Universidade da Coruña (1) · University Hospital, Grenoble (1) · University of Sharjah (1) · University of Texas Southwestern Medical Center (1) · İSMAİL CEYLAN (1)
United States (5) · Turkey (Türkiye) (4) · China (2) · Austria (1) · France (1) · Portugal (1) · Spain (1) · United Arab Emirates (1)
Eric Leuthardt, MD MBA (2) · Eric C Leuthardt, MD (1) · Jiang Du, M.D (1) · Noah Jouett, DO, PhD (1) · Olalla Bello, Lecturer (1) · Rudolf Likar, Prim. Univ.-Prof. Dr. MSc. (1) · Tamer M Shousha, PhD (1) · Thomas Ettenauer, Dr. (1)
PMID 38146234, PMID 38562875, PMID 38633771, PMID 38746275, PMID 39178291, PMID 39786346