50 completed, 11 terminated, 5 active not recruiting, 4 unknown. 25 Phase 2, 16 Phase 3, 13 Phase 4, 11 Phase 1, 10 Not applicable.
Follow ASA: new trials by email Literature Review of ASA trials Research Report on ASA
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in IntraCranial Atherosclerotic diseaSe (CATIS- ICAS) Rivaroxaban, ASA - Ischemic Stroke, Intracranial Atherosclerosis | Phase 3 | Not yet recruiting | Population Health Research Institute | 1172 | 2026-09-30 | 2026-09-01 |
| Effect of Low Molecular Heparin on Pregnancy Outcome With Protein S Deficiency Enoxaparin, Aspirin - Pregnancy Related, Protein S Deficiency | Phase 2 | Not yet recruiting | Peking University People's Hospital | 48 | 2024-08-01 | 2024-08-01 |
| APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia Aspirin 162 mg, Aspirin 81mg - Pre-Eclampsia, Pregnancy Loss | Phase 3 | Recruiting | University of Pennsylvania | 1150 | 2024-06-12 | 2026-09-10 |
| LDA and LMWH vs LDA Alone in High-risk Patients for Preeclampsia Prevention Aspirin, Tinzaparin - Preeclampsia Severe, Toxemia Of Pregnancy | Phase 4 | Recruiting | Alexandra Hospital, Athens, Greece | 100 | 2023-01-18 | 2026-01-23 |
| Study to Compare the Pharmacodynamics and Pharmacokinetics of Acetylsalicylic Acid Powder for Oral Inhalation With Non-enteric-coated Chewable Aspirin in Healthy Adults. ASA, non-enteric-coated chewable aspirin - Healthy Volunteers | Phase 1 | Completed | Vectura, Inc. | 86 | 2022-10-14 | 2024-03-22 |
| Predictors of Treatment Failure Pain Among Patients With Mine-explosive Wounds visual analog scale - Chronic Pain | Completed | Bogomolets National Medical University | 1166 | 2022-02-24 | 2022-08-01 | |
| Outpatient Liquid Aspirin (OLA) ASA - Covid19 | Phase 2 | Unknown | Louisiana State University Health Sciences Center in New Orleans | 200 | 2021-12-06 | 2022-01-03 |
| Effects of Edoxaban on Platelet Aggregation ASA, Clopidogrel, Edoxaban - SCAD, AMI | Phase 2 / Phase 3 | Completed | University of Sao Paulo | 61 | 2021-09-14 | 2025-04-27 |
| Low Molecular Weight hEparin vs. Aspirin Post-partum Prophylactic low molecular weight heparin, Low molecular weight heparin and low-dose aspirin - Venous Thromboembolism | Not applicable | Completed | Mount Sinai Hospital, Canada | 30 | 2021-08-29 | 2026-06-17 |
| The Role of Anthropometric Measurements and Ultrasonograpic Suprasternal Adipose Tissue Thickness Difficult Intubation, Not Difficult Intubation - Intubation; Difficult or Failed, Obesity | Completed | Ankara City Hospital Bilkent | 40 | 2021-01-01 | 2024-06-14 | |
| Pilot PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity Aspirin 81 mg, Placebo - Venous Thromboembolism, Postpartum Period | Early Phase 1 | Completed | University of Calgary | 257 | 2020-10-07 | 2023-09-13 |
| Efficacy and Safety of Apixaban in Reducing Restenosis and Limb Loss in PAD Patients. Apixaban, ASA, Clopidogrel 75mg - Critical Limb Ischemia | Phase 3 | Unknown | Science Valley Research Institute | 200 | 2020-01-09 | 2021-04-20 |
| Aspirin and Rintatolimod With or Without Interferon-alpha 2b in Treating Patients With Prostate Cancer Before Surgery EC Aspirin, Radical Prostatectomy, Recombinant Interferon Alfa-2b - Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8 | Phase 2 | Active not recruiting | Roswell Park Cancer Institute | 12 | 2019-11-29 | 2026-06-09 |
| Low Doses of Aspirin in the Prevention of Preeclampsia acetylsalicylic acid - Preeclampsia | Phase 3 | Completed | Weill Medical College of Cornell University | 400 | 2019-10-21 | 2025-03-13 |
| Aspirin as an Ultraviolet (UV) Protectant in Human Subjects at Risk for Melanoma Aspirin 81 mg, Aspirin 325mg, Placebo oral tablet - Melanoma (Skin) | Phase 2 | Completed | University of Utah | 95 | 2019-07-25 | 2022-02-18 |
| Rivaroxaban or Aspirin As Thromboprophylaxis in Multiple Myeloma Rivaroxaban, ASA - Multiple Myeloma in Relapse, Multiple Myeloma Progression | Phase 2 / Phase 3 | Unknown | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 57 | 2019-01-17 | 2024-02-29 |
| ASA in Prevention of Ovarian Cancer (STICs and STONEs) Acetylsalicylic acid, Placebo - Ovarian Cancer Prevention | Phase 2 | Active not recruiting | Canadian Cancer Trials Group | 117 | 2018-07-24 | 2026-09-16 |
| Anti-platelet + Pembro for H&N Tumors Pembrolizumab, Clopidogrel, acetylsalicylic acid - Head and Neck Cancer | Phase 1 | Completed | Medical University of South Carolina | 20 | 2018-03-06 | 2025-01-31 |
| LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic Oncology Aspirin 325mg, Enoxaparin 40Mg/0.4mL Prefilled Syringe - Sarcoma, Soft Tissue Sarcoma | Phase 4 | Enrolling by invitation | Massachusetts General Hospital | 2868 | 2018-02-16 | 2026-10-09 |
| Aspirin in Preventing Colorectal Cancer in Patients With Colorectal Adenoma Aspirin, Biospecimen Collection, Placebo Administration - Colorectal Adenoma, Colorectal Carcinoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 81 | 2018-01-16 | 2026-11-13 |
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Pre-Eclampsia (7) · Colorectal Neoplasms (5) · Coronary Artery Disease (5) · Myocardial Infarction (5) · Venous Thromboembolism (5) · Peptic Ulcer (4) · Atrial Fibrillation (3) · Stroke (3) · Thrombosis (3) · Tobacco Use Disorder (3) · Cardiovascular Diseases (2) · Colonic Neoplasms (2) · Fetal Growth Retardation (2) · Melanoma (2) · Multiple Sclerosis (2)
AstraZeneca (7) · National Cancer Institute (NCI) (7) · Biogen (2) · CHU de Quebec-Universite Laval (2) · Icahn School of Medicine at Mount Sinai (2) · M.D. Anderson Cancer Center (2) · Massachusetts General Hospital (2) · Mount Sinai Hospital, Canada (2) · Population Health Research Institute (2) · University of Florida (2) · University of Utah (2) · Alexandra Hospital, Athens, Greece (1) · Ankara City Hospital Bilkent (1) · Aragon Institute of Health Sciences (1) · Atrial Fibrillation Network (1)
United States (44) · Canada (13) · Italy (6) · Spain (6) · United Kingdom (6) · Germany (5) · Netherlands (5) · Belgium (4) · China (4) · Denmark (4) · Australia (3) · Austria (3) · Brazil (3) · Czechia (3) · France (3)
Dominick J Angiolillo, MD, PhD (2) · Douglas Grossman, MD (2) · Adrian F. Hernandez, MD MHS FAHA (1) · Amit Oza (1) · Amr M. Elkhouli, ph.D (1) · Andrea De Censi, MD (1) · Andrew T Chan, MD, MPH (1) · Angel Lanas Arbeloa, Physician (1) · Annika Strandell, Ass.prof. (1) · Atul Verma, MD (1) · Bernardo Bonanni (1) · Biren Saraiya, MD (1)
PMID 15842354, PMID 40875095, PMID 15132746, PMID 15189396, PMID 18094721, PMID 19878532, PMID 19923168, PMID 20620737, PMID 20626619, PMID 20637084, PMID 21079055, PMID 22078153, PMID 22212857, PMID 22409262, PMID 22795280, PMID 23903204, PMID 25999183, PMID 26503631, PMID 26725101, PMID 26986753, PMID 28316279, PMID 28768756, PMID 29948566, PMID 30095728, PMID 30400937, PMID 30514262, PMID 31174526, PMID 31664940, PMID 31998847, PMID 32057371, PMID 32186653, PMID 32358837, PMID 32466729, PMID 32678292, PMID 32730905, PMID 33476571, PMID 33687069, PMID 33779986, PMID 33999548, PMID 34389292, PMID 34566840, PMID 34582035, PMID 35876829, PMID 35999816, PMID 36322059, PMID 37025023, PMID 37345815, PMID 37489818, PMID 37622677, PMID 37792369
P30CA016672 (3), 2015 (2), N01CN00031 (2), N01CN00034 (2), P30CA023074 (2), 2014 (1), 2016 (1), N01CN00035 (1), N01CN35157 (1), P30CA015083 (1), P30CA060553 (1), P30CA072720 (1), P50CA090949 (1), R01CA113681 (1), R01CA137178 (1)