13 completed, 7 unknown, 2 withdrawn, 1 not yet recruiting. 6 Not applicable, 3 Phase 4, 2 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 4, Unknown 1, Withdrawn 1 |
| Phase 4 | 3 | Completed 2, Not yet recruiting 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Withdrawn 1 |
Follow Antidepressant: new trials by email Literature Review of Antidepressant trials Research Report on Antidepressant
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effective of Transcranial Magnetic Stimulation (TMS) vs Treatment as Usual for First-Episode Depression in Adults Transcranial magnetic stimulation, Antidepressant - Major Depressive Disorder | Phase 4 | Not yet recruiting | Sultan Qaboos University | 120 | 2025-01-01 | 2024-10-28 |
| The Efficacy of Tianeptine Versus Pregabalin on Acute and Chronic Post Mastectomy Pain After Breast Cancer Surgery. Pregabalin, Tianeptine - Post-mastectomy Pain Syndrome | Not applicable | Completed | National Cancer Institute, Egypt | 90 | 2023-06-21 | 2025-03-10 |
| Study of Virtual Reality-based Medical Device for Patients with Depressive Disorder OMNIFIT DTx-MDD, standard treatment - Depressive Disorder, Major Depressive Disorder | Not applicable | Completed | Omni C&S | 162 | 2023-03-09 | 2024-11-04 |
| Comparative Responses to 15 Different Antidepressants in Major Depressive Disorder Antidepressant - Major Depressive Disorder | Completed | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital | 73336 | 2022-10-01 | 2023-08-18 | |
| A Study to Assess Feasibility of Using Clinician-directed and Digital Application Supported Cognitive Behavior Therapy (CBT) in Conjunction With Esketamine in Participants With Treatment-resistant Depression Esketamine, Cognitive Behavioral Therapy (CBT), Antidepressant - Depression | Phase 1 | Withdrawn | Janssen Research & Development, LLC | 2022-09-01 | 2025-04-27 | |
| Association Between Prescription of Antidepressants and Delirium in the Elderly : Analysis From the World Health Organization Global Database Antidepressant - Antidepressive Agents, Aged | Unknown | University Hospital, Caen | 10000 | 2022-01-03 | 2022-05-02 | |
| Research on the Biological Mechanism of the Efficacy of Psychotherapy for Depression Based on the fNIRS Antidepressant, Psychotherapy IPT, The combination of antidepressant and IPT - Depressive Disorder | Not applicable | Unknown | First Affiliated Hospital of Zhejiang University | 90 | 2022-01-01 | 2023-07-03 |
| Precision Medicine for the Prediction of Treatment (PROMPT) Response (PROMPT) Antidepressant - Major Depressive Disorder | Unknown | University Hospital Muenster | 300 | 2021-09-09 | 2022-09-13 | |
| Treating Negative Affect in Low Back Pain Patients Antidepressant, Enhanced Fear Avoidance Rehabilitation - Chronic Low Back Pain, Negative Affectivity | Phase 2 | Completed | Ajay Wasan, MD, Msc | 308 | 2021-03-31 | 2026-08-28 |
| Neonatal Hypotonia Associated With in Utero Exposure to Antidepressant Antidepressant - Neonatal Hypotonia, Antidepressant Drug Adverse Reaction | Unknown | University Hospital, Caen | 10000 | 2021-03-25 | 2021-04-05 | |
| Multimodal Imaging of ECT Effects electroconvulsive therapy, Antidepressant - Major Depressive Disorder | Completed | Charite University, Berlin, Germany | 68 | 2017-09-01 | 2022-11-01 | |
| Eealy Improvement Predicts Antidepressants Response in Adults With Major Depression Disorder antidepressant - Major Depressive Disorder | Unknown | Huashan Hospital | 80 | 2017-07-25 | 2017-07-26 | |
| Early Improvement in Individual Symptoms and Response to Antidepressants in Patients With Major Depressive Disorder Antidepressant - Major Depressive Disorder | Unknown | University Medical Center Groningen | 10000 | 2016-09-01 | 2016-10-17 | |
| Use of Psychotropic Medications Among Pregnant Women With Bipolar Disorder Antipsychotic, Antidepressant, Antipsychotic and Antidepressant - Bipolar Disorder, Pregnancy Complications | Completed | Western University, Canada | 3357 | 2016-09-01 | 2018-05-11 | |
| Can Acupuncture Treat Post-stroke Depression? Dense cranial electroacupuncture stimulation, Body acupuncture, Antidepressant - Stroke, Depression | Not applicable | Completed | The University of Hong Kong | 91 | 2015-10-01 | 2019-05-20 |
| Comparative Effectiveness of Adaptive Treatment Strategies for Schizophrenia Antipsychotic, Antidepressant, Benzodiazepine - Schizophrenia, Schizoaffective Disorder | Completed | New York State Psychiatric Institute | 81921 | 2015-07-01 | 2024-05-01 | |
| Predictors of the Outcome of Late Life Depression Antidepressant, Psychoeducation, Treatment as usual (only pharmacological treatment). - Major Depression | Unknown | University of Sao Paulo General Hospital | 120 | 2015-04-01 | 2018-05-24 | |
| The ISLAND Study: InSuLa Assessed Needs for Depression Selective serotonin re-uptake inhibitor, Cognitive Behavioral Therapy, Combination treatment (SSRI + CBT) - Depression | Phase 4 | Completed | Emory University | 77 | 2014-09-01 | 2020-11-05 |
| CBT Versus Selective Serotonin Reuptake Inhibitor For Treatment Of Depression In Temporal Lobe Epilepsy Patients Cognitive behavioral therapy, SSRI - Depression, Epilepsy, Temporal Lobe | Not applicable | Completed | El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez | 15 | 2014-08-01 | 2015-03-30 |
| The Role of Antidepressants or Antipsychotics in Preventing Psychosis Antidepressant, Antipsychotic - Psychotic Disorder | Not applicable | Withdrawn | St. Luke's-Roosevelt Hospital Center | 2012-10-01 | 2014-05-26 |
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Depressive Disorder, Major (10) · Depression (9) · Anxiety Disorders (2) · Breast Neoplasms (2) · Chronic Pain (2) · Depressive Disorder (2) · Psychotic Disorders (2) · Bipolar Disorder (1) · Cognitive Dysfunction (1) · Consciousness Disorders (1) · Delirium (1) · Epilepsy (1) · Epilepsy, Temporal Lobe (1) · Fibromyalgia (1) · Hot Flashes (1)
University Hospital, Caen (2) · Ajay Wasan, MD, Msc (1) · Alliance for Clinical Trials in Oncology (1) · Charite University, Berlin, Germany (1) · El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez (1) · Emory University (1) · First Affiliated Hospital of Zhejiang University (1) · Huashan Hospital (1) · Janssen Research & Development, LLC (1) · Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital (1) · National Cancer Institute, Egypt (1) · New York State Psychiatric Institute (1) · Omni C&S (1) · St. Luke's-Roosevelt Hospital Center (1) · Stanford University (1)
United States (6) · China (2) · France (2) · Germany (2) · Brazil (1) · Denmark (1) · Egypt (1) · Hong Kong (1) · Mexico (1) · South Korea (1)
Ajay Wasan, MD, MSc (1) · Bernhard T. Baune, Professor (1) · Boadie W Dunlop, MD/MS (1) · Cassio MC Bottino, phD (1) · Charles L. Loprinzi, MD (1) · Daniel Crail-Melendez, MD (1) · Helen Lavretsky, M.D. (1) · Malek Bajbouj, MD (1) · Rachel Manber (1) · Salma Rose Imanari Ribeiz, phD (1) · Youngsup Woo (1)
PMID 17146104, PMID 19254516, PMID 27788313, PMID 29504795, PMID 30952216, PMID 33860531, PMID 33896622, PMID 36715655, PMID 36798983, PMID 38183804, PMID 38387672
R01MH073719 (1), UG3AR076568 (1)