13 completed, 3 not yet recruiting, 3 terminated, 3 unknown. 23 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 23 | Completed 13, Not yet recruiting 3, Terminated 3, Unknown 3, Withdrawn 1 |
Follow Amitriptyline: new trials by email Literature Review of Amitriptyline trials Research Report on Amitriptyline
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nortriptyline Compared With Amitriptyline for Migraine Prevention at SQUH Nortriptyline, Amitriptyline - Migraine | Phase 4 | Not yet recruiting | Sultan Qaboos University | 90 | 2027-05-01 | 2026-10-02 |
| Comparing Migraine Preventive Therapies vs. Anti-CGRP Therapies for Tinnitus in Patients With Migraine (COMPACT-PM) Galcanezumab, Erenumab 70 mg, Eptinezumab - Migraine Associated Vertigo, Tinnitus | Phase 4 | Not yet recruiting | Stanford University | 120 | 2026-07-01 | 2026-06-17 |
| Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary Care Topiramate, Flunarizine, Amitriptyline - Migraine | Phase 4 | Not yet recruiting | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | 460 | 2024-10-01 | 2024-07-12 |
| To Compare the Efficacy of Drugs in Combination for Treating Irritable Bowel Syndrome Associated With Diarrhea Rifaximin 550 MG, Mebeverine 135 MG, Psyllium Husk - Irritable Bowel Syndrome With Diarrhea | Phase 4 | Completed | Bahria University | 162 | 2023-01-03 | 2023-07-27 |
| Topiramate, Amitriptyline Monotherapy and Combination Therapy in Migraine Prophylaxis Topiramate 25Mg Tab, Amitriptyline 25 Mg Oral Tablet, topiramate 25mg plus amitriptyline 25mg - Migraine | Phase 4 | Unknown | Dr. Reaz Mahmud | 150 | 2022-08-22 | 2023-03-08 |
| Integrating a Stepped Care Model of Screening and Treatment for Depression Into Malawi's National HIV Care Delivery Platform Problem Management Plus, Antidepressant Therapy - Depressive Disorder | Phase 4 | Completed | RAND | 487 | 2021-09-01 | 2026-06-09 |
| Prospective, Cross Over Gabapentin vs Amitriptyline Study on Patients Suffering From Masticatory Muscle Pain Gabapentin, Amitriptyline - Myofacial Pain | Phase 4 | Unknown | Doron Aframian | 50 | 2015-02-01 | 2015-10-20 |
| Genetic Determinants of Amitriptyline Efficiency for Pain Treatment Amitriptyline, Tolterodine - Chronic Pain | Phase 4 | Completed | Insel Gruppe AG, University Hospital Bern | 48 | 2014-11-01 | 2019-01-24 |
| Genetic Determinants of Amitriptyline Efficiency for Pain Treatment - Part II Amitriptyline, Tolterodine - Chronic Pain | Phase 4 | Completed | Insel Gruppe AG, University Hospital Bern | 48 | 2014-11-01 | 2019-01-24 |
| Effects of Mesalamine and Amitriptyline on Irritable Bowel Syndrome Mesalazine(asacol 800 mg), Amitriptyline, placebo like asacol - Diarrhea- Predominant Irritable Bowel Syndrome, Quality of Life | Phase 4 | Withdrawn | Tehran University of Medical Sciences | 2014-09-01 | 2016-04-15 | |
| Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines SPG Block with 5% Lidocaine gel, Amitriptyline - Transformed Migraine, Chronic Daily Headache | Phase 4 | Terminated | Rutgers, The State University of New Jersey | 10 | 2014-05-01 | 2026-06-23 |
| Integrating Psychotropic Medication Into the Care of People With Mental Disorders in a Prayer Camp in Ghana olanzapine, risperidone, amitryptaline - Schizophrenia, Mood Disorders, | Phase 4 | Completed | University of Ghana Medical School | 139 | 2013-07-01 | 2015-11-02 |
| Low Doses Amitriptyline & Chronic Neck Pain Amitryptiline, Placebo - Neck Pain | Phase 4 | Completed | St Joseph University, Beirut, Lebanon | 212 | 2012-03-01 | 2017-08-29 |
| Effect of Minocycline on Pain Caused by Nerve Damage Minocycline, placebo, Amitriptyline - Neuropathic Pain Caused by Lumbar Radicular Pain | Phase 4 | Completed | Ziekenhuis Oost-Limburg | 60 | 2011-09-01 | 2015-01-27 |
| Optimizing Antidepressant Treatment by Genotype-dependent Adjustment of Medication According to the ABCB1 Gene Paroxetine, Sertraline, Citalopram - Major Depression | Phase 4 | Unknown | HolsboerMaschmeyer NeuroChemie GmbH | 80 | 2011-09-01 | 2014-09-12 |
| Comparative Efficacy and Tolerability of Quetiapine XR and Amitriptyline in the Treatment of Fibromyalgia amitriptyline, quetiapine - Fibromyalgia | Phase 4 | Completed | Universidad de Granada | 90 | 2008-11-01 | 2014-12-03 |
| Medical Therapies for Chronic Post-Traumatic Headaches Placebo, Propranolol, Amitriptyline - Headache | Phase 4 | Terminated | Madigan Army Medical Center | 64 | 2008-06-01 | 2013-04-23 |
| Excessive Crying in Children With Cerebral Palsy and Communication Deficits Placebo, Baclofen, Diazepam, Clonazepam, Trihexyphenidyl, Tetrabenazine, Gabapentin, Topiramate, Lamotrigine, Amitriptyline. - Cerebral Palsy, Excessive Crying | Phase 4 | Completed | Sathbhavana Brain Clinic | 131 | 2005-12-07 | 2021-10-28 |
| Effects of Amitriptyline for the Treatment of Pain on Driving Performance and Cognition. amitriptyline - Chronic Neuropathic Pain | Phase 4 | Terminated | UMC Utrecht | 24 | 2002-10-01 | 2005-09-16 |
| Study of Medication for Functional Abdominal Pain in Children Amitriptyline, Placebo - Functional Gastrointestinal Disorders | Phase 4 | Completed | Ann & Robert H Lurie Children's Hospital of Chicago | 95 | 2002-10-01 | 2007-11-28 |
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Chronic Pain (5) · Migraine Disorders (5) · Pain (3) · Depression (2) · Fibromyalgia (2) · Mood Disorders (2) · Neuralgia (2) · Abdominal Pain (1) · Amputation, Traumatic (1) · Anxiety Disorders (1) · Cerebral Palsy (1) · Deglutition Disorders (1) · Depressive Disorder (1) · Depressive Disorder, Major (1) · Diarrhea (1)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · Insel Gruppe AG, University Hospital Bern (2) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · Bahria University (1) · Doron Aframian (1) · Dr. Reaz Mahmud (1) · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina (1) · HolsboerMaschmeyer NeuroChemie GmbH (1) · Madigan Army Medical Center (1) · RAND (1) · Rutgers, The State University of New Jersey (1) · Sathbhavana Brain Clinic (1) · St Joseph University, Beirut, Lebanon (1) · Stanford University (1) · Sultan Qaboos University (1)
United States (6) · Switzerland (2) · Bangladesh (1) · Belgium (1) · Germany (1) · Ghana (1) · Iran (1) · Israel (1) · Lebanon (1) · Malawi (1) · Netherlands (1) · Oman (1) · Pakistan (1) · Spain (1)
Pascal H Vuilleumier, MD (2) · Ulrike Stamer, Professor (2) · Angela L Ofori-Atta, PhD (1) · Deborah R. Zucker (1) · Diana Cardenas, M.D. (1) · Doron J Aframian, DMD,PhD (1) · Edmund Volkerts, PhD (1) · Elena P Calandre, MD (1) · Florian Holsboer, MD, PHD (1) · Jan Van Zundert, MD, PhD (1) · Jay Erickson, MD (1) · Joseph Maarrawi, MD, PhD (1) · Kazi Gias Uddin Ahmed, FCPS, MD (1) · Kristen K. Steenerson (1) · Lawrence Robinson, MD, Professor (1)
PMID 17014022, PMID 19467572, PMID 22282331, PMID 22685578, PMID 23337936, PMID 29433613, PMID 34530894, PMID 37001058, PMID 37554074, PMID 39488229, PMID 40340587, PMID 40859286, PMID 41062145, PMID 41372945
P01HD033988 (2), 2005 (1), R01AR045416 (1)