9 completed, 4 unknown, 2 terminated, 1 withdrawn. 16 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 16 | Completed 9, Unknown 4, Terminated 2, Withdrawn 1 |
Follow Amantadine: new trials by email Literature Review of Amantadine trials Research Report on Amantadine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Antidepressant Augmentation With Amantadine vs Pramipexole vs Quetiapine in Treatment Resistant Depression Quetiapine, Amantadine, Pramipexole - Treatment Resistant Depression | Phase 4 | Unknown | All India Institute of Medical Sciences, Bhubaneswar | 150 | 2021-08-07 | 2023-08-22 |
| Effect of GOCOVRI (Amantadine, Extended Release Capsules) on Gait in Parkinson's Disease GOCOVRI - Parkinson Disease | Phase 4 | Completed | Oregon Health and Science University | 8 | 2020-11-05 | 2024-10-10 |
| Impact of Amantadine on Traumatic Brain Injury Amantadine (100mg) as add on therapy., Placebo - Trauma, Brain | Phase 4 | Completed | Damanhour University | 50 | 2020-09-30 | 2023-04-07 |
| Amantadine in Treating Cognitive & Motor Impairments in Adolescents and Adults With Cerebral Palsy Amantadine Hydrochloride - Cerebral Palsy | Phase 4 | Terminated | Columbia University | 11 | 2020-02-28 | 2022-05-31 |
| Evaluation of the Effect of Preoperative Intravenous Amantadine Sulfate on the Postoperative Early Cognitive Functions in a Elderly Patient With Laparoscopic Radical Prostatectomy Amantadine Sulfate, Placebo (for amantadine sulphate) - Postoperative Cognitive Dysfunction | Phase 4 | Unknown | TC Erciyes University | 54 | 2019-05-01 | 2019-06-20 |
| Citicholine-Amantadine Trial in Traumatic Brain Injury Citicholine, Amantadine - Intensive Care Unit | Phase 4 | Completed | Ain Shams University | 45 | 2017-12-07 | 2024-05-24 |
| Effect of Amantadine Administration on Spatial Functioning Following Traumatic Brain Injury Amantadine hydrochloride - Traumatic Brain Injury | Phase 4 | Unknown | Loewenstein Hospital | 10 | 2014-06-01 | 2018-08-08 |
| Effect of Intravenous Amantadine on Gait Freezing in Parkinson's Disease amantadine sulfate, 0.9% sodium chloride - Parkinson's Disease | Phase 4 | Completed | Jee-Young Lee | 46 | 2011-02-01 | 2012-08-09 |
| Validation of Dyskinesia Rating Scales Amantadine, Placebo - Parkinson's Disease | Phase 4 | Completed | Rush University Medical Center | 68 | 2010-01-01 | 2022-12-29 |
| Study of Amantadine for Risperidone Consta or Paliperidone Treated Patients to Decrease Prolactin Elevation Amantadine Hydrochloride, USP, Placebo - Schizophrenia, Schizoaffective Disorder | Phase 4 | Terminated | David C. Henderson, MD | 6 | 2009-10-01 | 2013-06-10 |
| Amantadine for Improving Neurologic Symptoms in Ataxia-Telangiectasia amantadine sulphate - Ataxia, Chorea | Phase 4 | Completed | Sheba Medical Center | 30 | 2008-11-01 | 2011-06-28 |
| Long-Term Effects of Amantadine in Parkinsonian (AMANDYSK) mantadix - Parkinson's Disease | Phase 4 | Completed | University Hospital, Toulouse | 80 | 2007-11-01 | 2011-04-08 |
| Amantadine for the Treatment of Behavioral Disturbance in Frontotemporal Dementia (FTD) Amantadine, Placebo - Dementia | Phase 4 | Withdrawn | Johns Hopkins University | 2005-09-01 | 2017-08-14 | |
| Amantadine for Treatment of Symptoms of the Post-traumatic Confusional State Amantadine hydrochloride, Placebo capsule - Traumatic Brain Injury, Posttraumatic Confusional State | Phase 4 | Completed | Methodist Rehabilitation Center | 79 | 2003-04-01 | 2023-10-18 |
| Peginterferon Alfa-2a, Ribavirin, Amantadine/Placebo in Hepatitis C Virus (HCV)-Genotype-1-Infection (PRAMA) Amantadine sulphate (in addition to standard treatment) - Hepatitis C, Chronic | Phase 4 | Unknown | University Hospital, Saarland | 700 | 2002-07-01 | 2005-08-25 |
| Modeling Impaired Judgement in Cocaine Abusers - 6 Amantadine - Cocaine-Related Disorders, Substance-Related Disorders | Phase 4 | Completed | National Institute on Drug Abuse (NIDA) | 1997-03-01 | 2017-01-12 |
Parkinson Disease (4) · Brain Injuries, Traumatic (3) · Dyskinesias (2) · Ataxia (1) · Brain Injuries (1) · Cerebral Palsy (1) · Chorea (1) · Cocaine-Related Disorders (1) · Delirium (1) · Dementia (1) · Depressive Disorder, Treatment-Resistant (1) · Dystonia (1) · Fatigue (1) · Frontotemporal Dementia (1) · Hepatitis C, Chronic (1)
Ain Shams University (1) · All India Institute of Medical Sciences, Bhubaneswar (1) · Columbia University (1) · Damanhour University (1) · David C. Henderson, MD (1) · Jee-Young Lee (1) · Johns Hopkins University (1) · Loewenstein Hospital (1) · Methodist Rehabilitation Center (1) · National Institute on Drug Abuse (NIDA) (1) · Oregon Health and Science University (1) · Rush University Medical Center (1) · Sheba Medical Center (1) · TC Erciyes University (1) · University Hospital, Saarland (1)
United States (7) · Egypt (2) · France (2) · Israel (2) · Austria (1) · Canada (1) · India (1) · South Korea (1) · Turkey (Türkiye) (1)
Amie Hiller, MD (1) · Andreea Nissenkorn, MD (1) · Christopher G Goetz, MD (1) · David C. Henderson, M.D. (1) · David M Blass, M.D. (1) · Debadatta Mohapatra, MD (1) · Glenn T Stebbins, PhD (1) · Gulen Guler (1) · Heakyung Kim, MD (1) · Jinwhan Cho, M.D.,Ph.D. (1) · John Rotrosen, M.D. (1) · Mark Sherer, Ph.D. (1) · Olivier Rascol, MD (1) · Rehab H Werida, Lecturer (1) · Risa N Richardson, Ph.D. (1)
PMID 10082232, PMID 12648190, PMID 15374380, PMID 18058285, PMID 19752841, PMID 22550086, PMID 25251457, PMID 27733282, PMID 27848269, PMID 40659070, PMID 8827185, PMID 9525362