18 completed, 3 unknown, 1 terminated, 1 withdrawn. 23 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 23 | Completed 18, Unknown 3, Terminated 1, Withdrawn 1 |
| Phase 2 | 4 | Completed 4 |
Follow alpha-Tocopherol: new trials by email Literature Review of alpha-Tocopherol trials Research Report on alpha-Tocopherol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effectiveness of Vitamin E and Hydrogen-Rich Water on Radiation Therapy-Induced Adverse In Patients With Rectal Cancer Vitamin E, Hydrogen rich water, placebo - Radiation-induced Injuries in Patients With Rectal Cancer | Phase 3 | Unknown | University of Jordan | 60 | 2019-07-06 | 2021-02-17 |
| Clinical Benefit of Spa Care on Severe Radiation-induced Fibrosis After Postoperative Radiotherapy for Breast Cancer skin-oriented spa care, Pentoxifylline, Tocopherol acetate - Breast Carcinoma, Fibrosis | Phase 3 | Unknown | Institut de Cancérologie de Lorraine | 142 | 2018-12-01 | 2018-08-08 |
| Hydroxytyrosol and Vitamin E in Pediatric NASH Hydroxytyrosol plus Vitamin E, Placebo - NAFLD | Phase 3 | Completed | Bambino Gesù Hospital and Research Institute | 80 | 2017-04-01 | 2018-07-17 |
| Efficacy of Vitamin E in Preventing Contrast-Induced Acute Kidney Injury Following Coronary Angiography Vitamin E - Stable Angina, Unstable Angina | Phase 3 | Completed | Urmia University of Medical Sciences | 284 | 2014-02-01 | 2015-06-16 |
| Vitamin E Supplementation in Burned Patients Vitamin E - Burn | Phase 2 / Phase 3 | Completed | The University of Texas Medical Branch, Galveston | 27 | 2013-02-01 | 2026-07-20 |
| Lactation Fortification Study Similac Prenatal Vitamin soft-gel capsule, Placebo (soybean oil and dl-alpha-tocopheryl acetate) - Lactation | Phase 3 | Completed | Abbott Nutrition | 89 | 2012-11-01 | 2013-05-31 |
| Study of the Absorption of Vitamin E Water-soluble Form (Pegylated) in the Familial Hypocholesterolemia With Chylomicron Retention Tocofersolan, tocopherol alpha, Tocofersolan and tocopherol alpha - Hypobetalipoproteinemias | Phase 3 | Completed | Hospices Civils de Lyon | 14 | 2011-10-01 | 2025-08-22 |
| Trial of Combined Pentoxifylline-tocopherol-clodronate vs Placebo in Radiation-induced Brachial Plexopathy Pentoxifylline placebo, Pentoxifylline, Tocopherol acetate - Radiation Induced Brachial Plexopathy | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 59 | 2011-03-01 | 2017-12-08 |
| Efficacy of Alpha Tocopherol for Prevention of Contrast-induced Nephropathy in Chronic Kidney Disease (CKD) Patients alpha tocopherol, placebo - Contrast Induced Nephropathy | Phase 3 | Unknown | Thammasat University | 200 | 2010-01-01 | 2010-02-03 |
| Type 2 Diabetes Haptoglobin Phenotype and Vitamin E Vitamin E (d-alpha-tocopheryl acetate), Placebo - Diabetes Mellitus Type 2 | Phase 2 / Phase 3 | Completed | Technion, Israel Institute of Technology | 90 | 2009-01-01 | 2011-01-11 |
| Biomarker Study of Neoadjuvant Vitamin E in Patients With Locally Treatable Prostate Cancer Vitamin E - Prostate Cancer | Phase 3 | Terminated | New Mexico Cancer Research Alliance | 15 | 2008-09-01 | 2015-07-16 |
| S0000D: Effect of Vitamin E and/or Selenium on Colorectal Polyps in Men Enrolled on SELECT Trial SWOG-S0000 Vitamin E, Selenium, Vitamin E placebo - Colorectal Cancer, Precancerous Condition | Phase 3 | Completed | SWOG Cancer Research Network | 8094 | 2008-06-01 | 2019-12-16 |
| Impact of Oral Versatile Antioxidants on Glaucoma Progression Gingko Biloba, α-tocopherol, Placebo - Glaucoma | Phase 3 | Completed | Bagcilar Training and Research Hospital | 60 | 2008-04-01 | 2012-03-05 |
| A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease dl-alpha-tocopherol, Memantine, Placebo - Alzheimer's Disease | Phase 3 | Completed | US Department of Veterans Affairs | 613 | 2007-08-01 | 2014-07-23 |
| S0000B: Vitamin E and/or Selenium in Preventing Cataract and Age-Related Macular Degeneration in Men on SELECT SWOG-S0000 selenium, vitamin E, vitamin E placebo - Cataract, Macular Degeneration | Phase 3 | Completed | SWOG Cancer Research Network | 13475 | 2004-07-01 | 2019-08-14 |
| Combined Antioxidant and Preeclampsia Prediction Studies (CAPPS) Dietary Supplement/Vitamins, Placebo for Vitamin C and Vitamin E - Preeclampsia | Phase 3 | Completed | The George Washington University Biostatistics Center | 10154 | 2003-06-01 | 2019-02-21 |
| Effect of Vitamin E on Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) Vitamin treatment (alpha tocopherol plus ascorbic acid), Placebo - Inflammation, Fibrosis | Phase 2 / Phase 3 | Completed | Bambino Gesù Hospital and Research Institute | 90 | 2003-01-01 | 2008-04-09 |
| S0000 Selenium and Vitamin E in Preventing Prostate Cancer Vitamin E, Selenium, Vitamin E placebo - Prostate Cancer | Phase 3 | Completed | SWOG Cancer Research Network | 35533 | 2001-07-01 | 2015-11-20 |
| Multicenter Vitamin E Trial in Aging Persons With Down Syndrome Alpha-Tocopherol, Sugar Pill - Alzheimer's Disease, Down Syndrome | Phase 3 | Completed | New York State Institute for Basic Research | 349 | 2000-09-01 | 2012-05-09 |
| VEAPS: Vitamin E Atherosclerosis Prevention Study DL-alpha-tocopherol - Atherosclerosis | Phase 2 / Phase 3 | Completed | National Institute on Aging (NIA) | 353 | 1996-07-01 | 2009-12-11 |
Showing 20 of 23. Sign in to see all of them.
Alzheimer Disease (2) · Fibrosis (2) · Inflammation (2) · Non-alcoholic Fatty Liver Disease (2) · Prostatic Neoplasms (2) · Adenomatous Polyps (1) · Angina, Stable (1) · Angina, Unstable (1) · Atherosclerosis (1) · Breast Feeding (1) · Breast Neoplasms (1) · Burns (1) · Carcinoma, Non-Small-Cell Lung (1) · Cataract (1) · Cognitive Dysfunction (1)
SWOG Cancer Research Network (3) · Bambino Gesù Hospital and Research Institute (2) · Abbott Nutrition (1) · Assistance Publique - Hôpitaux de Paris (1) · Bagcilar Training and Research Hospital (1) · Helse Stavanger HF (1) · Hospices Civils de Lyon (1) · Institut de Cancérologie de Lorraine (1) · Laval University (1) · M.D. Anderson Cancer Center (1) · National Institute on Aging (NIA) (1) · New Mexico Cancer Research Alliance (1) · New York State Institute for Basic Research (1) · Technion, Israel Institute of Technology (1) · Thammasat University (1)
United States (9) · France (3) · Italy (2) · Canada (1) · Iran (1) · Israel (1) · Norway (1) · Palestinian Territories (1) · Puerto Rico (1) · Thailand (1) · Turkey (Türkiye) (1)
Adis Tasanarong, MD (1) · Andrew Levy, MD PhD (1) · Christina Sherry, PhD, RD (1) · Daniel D Karp, M.D. (1) · Dennis WT Nilsen, PhD (1) · Eric Klein, MD (1) · Fadlo R. Khuri, M.D. (1) · Howard F. Andrews, Ph.D. (1) · Howard N. Hodis, MD (1) · Ian M. Thompson, M.D. (1) · Ian Rabinowitz, M.D. (1) · Isabelle Bairati, MD, PhD (1) · J. Michael Gaziano, M.D. (1) · James M Roberts, MD (1) · Jan Slezak, Professor (1)
PMID 27519183, PMID 12234947, PMID 15812073, PMID 16027437, PMID 16841333, PMID 17206944, PMID 17927499, PMID 18059031, PMID 18172254, PMID 19066370, PMID 19451440, PMID 19845233, PMID 20103685, PMID 20156960, PMID 20187097, PMID 20375405, PMID 20533282, PMID 20733448, PMID 20833684, PMID 21424341, PMID 21640495, PMID 21722898, PMID 21990298, PMID 22009713, PMID 22076708, PMID 22742890, PMID 23064404, PMID 23169318, PMID 23171483, PMID 24381967, PMID 24899160, PMID 25232809, PMID 27068631, PMID 27173062, PMID 27197287, PMID 27998216, PMID 28791297, PMID 30021760, PMID 32312759, PMID 33060043, PMID 42581651
U10CA037429 (3), 2016 (1), P30CA016672 (1), R01AG013860 (1), R01AG016381 (1), R01EY014418 (1), R03CA141615 (1), U01HD036801 (1), U10HD021410 (1), U10HD027860 (1), U10HD027869 (1), U10HD027915 (1), U10HD027917 (1), U10HD034116 (1), U10HD034136 (1)