3 completed, 3 recruiting, 2 not yet recruiting, 1 active not recruiting. 6 Not applicable, 3 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Recruiting 3, Not yet recruiting 2, Active not recruiting 1 |
| Phase 3 | 3 | Completed 2, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow Walking Impairment: new trials by email Literature Review of Walking Impairment trials Research Report on Walking Impairment
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Closed-Loop Vagus Nerve Stimulation (CLV) for Recovery of Gait After Spinal Cord Injury (SCI) CLV, Sham - Spinal Cord Injury (SCI), Gait | Not applicable | Not yet recruiting | The University of Texas at Dallas | 20 | 2026-09-30 | 2026-07-27 |
| Body Weight-Supported and Virtual Reality Gait Training in Stroke Patients Virtual Reality-Assisted Gait Training, Backward Gait Training, Forward Gait Training - Stroke, Walking Impairment | Not applicable | Recruiting | Gaziler Physical Medicine and Rehabilitation Education and Research Hospital | 30 | 2026-03-26 | 2026-04-24 |
| Investigating the Mechanisms of Welwalk Robot in Restoring Motor Function of the Lower Extremities in Stroke Patients welwalk training, physical therapy - Stroke, Walking Impairment | Not applicable | Not yet recruiting | Ruijin Hospital | 38 | 2025-07-01 | 2025-07-10 |
| Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking rTMS, AEx - Stroke, Depression - Major Depressive Disorder | Not applicable | Recruiting | Medical University of South Carolina | 96 | 2024-11-01 | 2026-08-04 |
| Exercise Training, Cognition, and Mobility in Older Adults With Multiple Sclerosis Aerobic and Resistance Exercise Program (GEMS program), Flexibility and Stretching Program (FLEX-MS program) - Older Adults, Multiple Sclerosis | Not applicable | Active not recruiting | University of Illinois at Chicago | 51 | 2023-07-05 | 2025-02-27 |
| Clinical Impacts of Structured Robotic Gait Training Programs Clinical Impacts of Structured Robotic Gait Training Programs - Neuromotor Impairments, Walking Impairment | Not applicable | Recruiting | University of Calgary | 120 | 2022-11-01 | 2026-02-12 |
| A Safety and Efficacy Study of ADS-5102 in Patients With Multiple Sclerosis and Walking Impairment ADS-5102, 274 mg - Multiple Sclerosis, Walking Impairment | Phase 3 | Completed | Adamas Pharmaceuticals, Inc. | 424 | 2018-07-18 | 2022-01-18 |
| Safety and Efficacy of ADS-5102 in Multiple Sclerosis Patients With Walking Impairment ADS-5102, 137 mg, ADS-5102, 274 mg, Placebo - Walking Impairment, Multiple Sclerosis | Phase 3 | Completed | Adamas Pharmaceuticals, Inc. | 558 | 2018-03-29 | 2021-12-21 |
| Safety and Efficacy of ADS-5102 in Patients With Multiple Sclerosis and Walking Impairment ADS-5102, Placebo - Walking Impairment, Multiple Sclerosis | Phase 2 | Completed | Adamas Pharmaceuticals, Inc. | 60 | 2015-05-01 | 2017-08-08 |
| Treadmill Training at Constant or Different Speeds for People With Traumatic Brain Injury Gait Training Method - Traumatic Brain Injury, Walking Impairment | Phase 3 | Terminated | National Institutes of Health Clinical Center (CC) | 1 | 2011-07-29 | 2019-12-16 |
Multiple Sclerosis (4) · Stroke (3) · Motor Activity (2) · Brain Injuries, Traumatic (1) · Cognitive Dysfunction (1) · Spinal Cord Injuries (1)
Nervous System Diseases (9) · Central Nervous System Diseases (5) · Autoimmune Diseases (4) · Autoimmune Diseases of the Nervous System (4) · Brain Diseases (4) · Demyelinating Autoimmune Diseases, CNS (4) · Demyelinating Diseases (4) · Immune System Diseases (4) · Cardiovascular Diseases (3) · Cerebrovascular Disorders (3) · Vascular Diseases (3) · Behavior (2) · Trauma, Nervous System (2) · Wounds and Injuries (2) · Brain Injuries (1)
Physical Therapy Modalities (1) · Pliability (1)
Adamas Pharmaceuticals, Inc. (3) · Gaziler Physical Medicine and Rehabilitation Education and Research Hospital (1) · Medical University of South Carolina (1) · National Institutes of Health Clinical Center (CC) (1) · Ruijin Hospital (1) · The University of Texas at Dallas (1) · University of Calgary (1) · University of Illinois at Chicago (1)
United States (7) · Canada (3) · China (1) · Turkey (Türkiye) (1)
Chad Swank, PhD (1) · Diane L Damiano, Ph.D. (1) · Jane Wigginton, MD (1) · Michael Foreman, MD (1) · Peixuan Zheng, PhD (1) · Rita Hamilton, DO (1) · Robert Rennaker, PhD (1) · Seth Hays, PhD (1)
PMID 19629252, PMID 22165907, PMID 32506008, PMID 33069609, PMID 33526065, PMID 33675076, PMID 37490379, PMID 38647534, PMID 39038700, PMID 39871991, PMID 39973293, PMID 40140968, PMID 40319228, PMID 40341197, PMID 40533805
5UG3NS131971-02 (1), R01HD113299 (1)