46 completed, 23 recruiting, 12 unknown, 9 active not recruiting. 34 Not applicable, 22 Phase 2, 12 Phase 3, 8 Phase 1, 1 Phase 4.
Follow Vulvar Cancer: new trials by email Literature Review of Vulvar Cancer trials Research Report on Vulvar Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Radiotherapy for Gynecologic Cancer With Up to 10 Active Metastatic Lesions Routine-care metastasis-directed radiotherapy - Cervical Cancer, Gynecologic Cancer | Recruiting | Affidea Nu-med Center of Oncological DIagnostics and Therapy | 500 | 2026-10-06 | 2026-10-20 | |
| Intraoperative Microscopic Assessment of Lymph Node Status in Gynecological Malignancies Gynecologic Cancer, Cervical Cancer | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 160 | 2026-08-01 | 2026-07-14 | |
| Cancer Loyalty Card Study 2 (CLOCS-2) Cases & Controls - Pancreatic Cancer, Colon Cancer | Recruiting | Imperial College London | 2900 | 2026-02-04 | 2026-03-25 | |
| DESTINY-PANTUMOUR04 Trastuzumab deruxtecan - Adenocarcinoma (NOS), Anal Cancer | Recruiting | AstraZeneca | 100 | 2025-09-18 | 2026-09-25 | |
| Near-Infrared Fluorescence Imaging With Indocyanine Green to Evaluate Bowel Anastomoses in Gynecologic Oncology Surgery Indocyanine Green, Near-Infrared Fluorescence Imaging System - Gynecologic Cancers, Ovarian Cancer | Phase 4 | Not yet recruiting | Istanbul University | 50 | 2025-09-01 | 2025-03-14 |
| E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers E7 TCR-T cells, Aldesleukin - HPV-Associated Cervical Carcinoma, HPV-Related Carcinoma | Phase 1 / Phase 2 | Recruiting | Christian Hinrichs | 15 | 2025-08-11 | 2026-10-06 |
| Belzutifan in Recurrent Clear Cell Carcinoma of Gynecologic Origin Belzutifan - Ovarian Cancer, Ovarian Carcinoma | Phase 2 | Recruiting | Dana-Farber Cancer Institute | 32 | 2024-12-20 | 2025-11-05 |
| STRatIfication of Vulvar Squamous Cell Carcinoma by HPV and p53 Status to Guide Excision Re-excision - Vulvar Cancer | Not applicable | Recruiting | British Columbia Cancer Agency | 249 | 2024-11-25 | 2026-02-03 |
| Enhanced Assistance During Radiotherapy for Unmet Essential Needs Standard assistance, Enhanced assistance - Bone Cancer, Brain Cancer | Not applicable | Completed | Washington University School of Medicine | 33 | 2024-10-04 | 2025-08-26 |
| UNDERSTANDING the RAREST GYNECOLOGICAL CANCERS: a MULTI -OMICS PLATFORM for IMPROVED PATIENTS MANAGEMENT DNA, RNA, ctDNA, metabolomics - Uterine Sarcoma, Vulvar Cancer | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 190 | 2024-09-15 | 2024-09-03 | |
| Danish Vulva Cancer Recurrence Study Measurement of circulating tumor-DNA, Collection of patient-reported outcomes, Algorithmically determined telephone interview with a nurse - Vulva Cancer, Vulva Neoplasm | Not applicable | Recruiting | University of Aarhus | 1295 | 2024-08-15 | 2026-04-29 |
| ASk Questions in GYnecologic Oncology (ASQ-GYO) Administration of the ASk Questions in GYnecologic Oncology (ASQ-GYO) Question Prompt List - Ovarian Cancer, Endometrial Cancer | Not applicable | Completed | Ira Winer | 68 | 2024-04-04 | 2026-08-20 |
| A Three-arm Randomized Phase II Study of Dostarlimab Alone or With Bevacizumab Versus Nonplatinum Chemotherapy in Recurrent Gynecological Clear Cell Carcinoma: DOVE (APGOT-OV7/ ENGOT-ov80 Study) Dostarlimab, Bevacizumab, Doxorubicin - Ovarian Neoplasms, Endometrial Neoplasms | Phase 2 | Recruiting | Yonsei University | 198 | 2024-01-22 | 2026-05-06 |
| Vulvar Cancer Individualized Scoring System (VCISS) Machine learning-based prediction model - Vulvar Cancer | Unknown | Assiut University | 1000 | 2024-01-01 | 2023-08-23 | |
| Using Reiki Therapy to Improve Symptoms Associated With Brachytherapy in Patients With Gynecological Malignancies Reiki therapy - Gynecologic Neoplasm, Brachytherapy | Phase 2 | Recruiting | University of Utah | 70 | 2023-11-14 | 2026-10-14 |
| Study of Near-Infrared Imaging With Indocyanine Green for Detection of Sentinel Lymph Nodes in People With Vulvar Cancer ICG guided sentinel lymph node biopsy - Vulvar Cancer | Not applicable | Active not recruiting | Memorial Sloan Kettering Cancer Center | 22 | 2023-11-06 | 2025-11-05 |
| Indocyanine Green for Detection of Sentinel Lymph Nodes In Comparison to ICG Plus Technetium in the Evaluation of Vulvar Squamous Cell Carcinoma ICG alone - Vulvar Cancer | Recruiting | Hamilton Health Sciences Corporation | 58 | 2023-10-01 | 2026-04-13 | |
| Physical Activity Intervention Among Older Women With Gynecologic Cancers (Fit4Treatment) Fit4Treatment - Ovary Cancer, Endometrial Cancer | Not applicable | Active not recruiting | Northwestern University | 192 | 2023-09-15 | 2026-10-19 |
| Immunotherapy-related CRP Kinetics in Metastatic Gynecological Malignancies Gynecological Malignancies, Cervical Cancer | Recruiting | University Hospital Tuebingen | 120 | 2023-09-11 | 2026-02-10 | |
| AK104 for Recurrent or Metastatic Vulvar Cancer AK104, AK104+ Paclitaxel+Cisplatin or Carboplatin - Vulvar Cancer | Phase 2 | Terminated | Akeso | 20 | 2023-08-25 | 2026-09-28 |
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Vulvar Neoplasms (102) · Uterine Cervical Neoplasms (65) · Vaginal Neoplasms (46) · Ovarian Neoplasms (35) · Endometrial Neoplasms (30) · Uterine Neoplasms (18) · Fallopian Tube Neoplasms (16) · Anus Neoplasms (15) · Sarcoma (14) · Condylomata Acuminata (12) · Papillomavirus Infections (11) · Esophageal Neoplasms (10) · Penile Neoplasms (10) · Carcinoma, Ovarian Epithelial (9) · Breast Neoplasms (8)
Female Urogenital Diseases (102) · Female Urogenital Diseases and Pregnancy Complications (102) · Genital Diseases (102) · Genital Diseases, Female (102) · Neoplasms by Site (102) · Urogenital Diseases (102) · Urogenital Neoplasms (102) · Vulvar Diseases (101) · Genital Neoplasms, Female (99) · Neoplasms (97) · Uterine Diseases (68) · Uterine Cervical Diseases (65) · Uterine Neoplasms (50) · Vaginal Diseases (46) · Endocrine Gland Neoplasms (39)
Cisplatin (4) · Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18 (4) · Methods (4) · Radiotherapy (4) · Surveys and Questionnaires (4) · pembrolizumab (3) · Bleomycin (2) · Carboplatin (2) · Drug Therapy (2) · Electrochemotherapy (2) · Paclitaxel (2) · Sentinel Lymph Node Biopsy (2) · Vaccines, Synthetic (2) · Adoptive Transfer (1) · Amplified Fragment Length Polymorphism Analysis (1)
Merck Sharp & Dohme LLC (8) · Shanghai Bovax Biotechnology Co., Ltd. (5) · Gynecologic Oncology Group (4) · Memorial Sloan Kettering Cancer Center (4) · Royal Marsden NHS Foundation Trust (3) · British Columbia Cancer Agency (2) · Catholic University of the Sacred Heart (2) · Dana-Farber Cancer Institute (2) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (2) · Institute of Oncology Ljubljana (2) · Masonic Cancer Center, University of Minnesota (2) · National Cancer Institute (NCI) (2) · Northwestern University (2) · Abramson Cancer Center at Penn Medicine (1) · Affidea Nu-med Center of Oncological DIagnostics and Therapy (1)
United States (41) · United Kingdom (12) · China (9) · Canada (7) · Italy (7) · France (4) · Sweden (3) · Belgium (2) · Denmark (2) · Germany (2) · Netherlands (2) · Slovenia (2) · Australia (1) · Austria (1) · Botswana (1)
Clare Shaw, Phd (3) · Levi S. Downs, MD (2) · Akila Viswanathan, M.D. (1) · Amy Jamieson, MD (1) · Anna Fagotti (1) · Barry L. Gause, MD (1) · Beate Senn, PhD, RN (1) · Bernadette Cracchiolo, MD, MPH (1) · Calum MacAulay, Ph.D. (1) · Catherine West (1) · Charles Levenback, MD (1) · Charlotte C. Sun, MD (1) · Christian S Hinrichs, MD (1)
PMID 27422279, PMID 29269325, PMID 29767739, PMID 33326342, PMID 18482765, PMID 18768432, PMID 19487487, PMID 19701032, PMID 20686386, PMID 22675922, PMID 22753905, PMID 23107862, PMID 23290987, PMID 23384847, PMID 23526734, PMID 23535473, PMID 23849695, PMID 25278227, PMID 25693011, PMID 25749310, PMID 25912208, PMID 26086587, PMID 26101366, PMID 26366475, PMID 27865255, PMID 28653559, PMID 28789851, PMID 28886907, PMID 29149611, PMID 29211620, PMID 30943124, PMID 30982556, PMID 31350251, PMID 31586247, PMID 31682550, PMID 31980466, PMID 32359091, PMID 32375773, PMID 32659510, PMID 32919526, PMID 33676783, PMID 33836153, PMID 33882792, PMID 34108183, PMID 34253678, PMID 34990208, PMID 35114169, PMID 35361487, PMID 35588692, PMID 35680043
2009 (1), 2015 (1), 2016 (1), 2019 (1), P30CA012197 (1), P30CA014520 (1), P30CA043703 (1), P30CA060553 (1), R01CA236546 (1), R21CA167800 (1)