3069 completed. 3069 Phase 2, 550 Phase 1, 295 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3069 | Completed 3069 |
| Phase 1 | 550 | Completed 550 |
| Phase 3 | 295 | Completed 295 |
Follow Vascular Diseases: new trials by email Literature Review of Vascular Diseases trials Research Report on Vascular Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of the SCD411 Prefilled Syringe for Treating Adults With Wet Age-Related Macular Degeneration, Retinal Vein Occlusion, Diabetic Macular Edema, or Diabetic Retinopathy SCD411 0.05mL (2mg) - Neovascular (Wet) Age-Related Macular Degeneration, Retinal Vein Occlusion | Phase 2 | Completed | Sam Chun Dang Pharm. Co. Ltd. | 33 | 2026-05-13 | 2026-06-08 |
| Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation QLS-111 Ophthalmic Solution (0.015%), QLS-111 Ophthalmic Solution (0.075%) - Non-proliferative Diabetic Retinopathy (NPDR), Open-angle Glaucoma (OAG) | Phase 2 | Completed | Qlaris Bio, Inc. | 9 | 2026-02-20 | 2026-11-02 |
| A Study of Weekly Oral Ecnoglutide (VRB-101) in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities VRB-101, Placebo - Obesity, Overweight | Phase 2 | Completed | Verdiva Bio Dev Limited | 206 | 2025-11-25 | 2026-08-17 |
| HRS-7450 Injection Phase II Clinical Trial for Acute Ischemic Stroke. HRS-7450 Injection, HRS-7450 Injection Placebo - Acute Ischemic Stroke | Phase 2 | Completed | Fujian Shengdi Pharmaceutical Co., Ltd. | 210 | 2025-10-31 | 2026-10-20 |
| Evaluation Study of Early Administration of Evolocumab After Thrombolysis in Patients With Atherosclerotic Acute Ischemic Stroke Ivolumab 420mg (three vials) - Acute Stroke | Phase 2 | Completed | The Affiliated Hospital of Xuzhou Medical University | 132 | 2025-10-30 | 2026-09-10 |
| A Clinical Trial of MT200605 for the Treatment of Acute Ischemic Stroke MT200605, Placebo - Acute Ischemic Stroke | Phase 2 | Completed | Shaanxi Micot Pharmaceutical Technology Co., Ltd. | 360 | 2025-09-30 | 2026-11-05 |
| Combined Antiplatelet Strategy in Acute Ischemic Stroke Following Thrombectomy and/or Intravenous Thrombolysis (CoPRIME) aspirin + clopidogrel, Aspirin - Acute Ischemic Stroke | Phase 2 | Completed | University of Alberta | 3 | 2025-09-02 | 2026-09-28 |
| Clopidogrel Plus Aspirin in Acute Ischemic Stroke Following Thrombectomy and/or Intravenous Thrombolysis (CoPrime) aspirin + clopidogrel, Aspirin - Acute Ischemic Stroke | Phase 2 | Completed | University of Alberta | 3 | 2025-09-02 | 2026-07-16 |
| Dexrazoxane to Protect Against Hemorrhagic STEMI Dexrazoxane, Normal Saline - Acute Myocardial Infarction (AMI) | Phase 2 | Completed | Rohan Dharmakumar | 50 | 2025-08-30 | 2026-05-26 |
| Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT) Sildenafil 25 MG, Placebo - Pulmonary Hypertension, Rheumatic Valvular Heart Disease | Phase 2 / Phase 3 | Completed | Sindh Institute of Cardiovascular Diseases | 100 | 2025-08-01 | 2026-09-24 |
| A Clinical Study to Investigate the Effect of Oral Neflamapimod on Motor Recovery After Acute Ischaemic Stroke Neflamapimod, Placebo - Moderate to Severe Acute Ischaemic Stroke, Ischaemic Stroke | Phase 2 | Completed | EIP Pharma Inc | 45 | 2025-06-20 | 2026-10-28 |
| A Study to Assess TTI-0102 vs Placebo in MELAS Patients TTI-0102, Placebo - MELAS Syndrome, Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS) | Phase 2 | Completed | Thiogenesis Therapeutics, Inc. | 9 | 2025-05-12 | 2026-07-24 |
| A Study of REGN7544 for the Treatment in Adult Patients With Sepsis-Induced Hypotension REGN7544, PB - Sepsis-Induced Hypotension | Phase 2 | Completed | Regeneron Pharmaceuticals | 76 | 2025-05-05 | 2026-05-20 |
| A Study to Investigate Tonlamarsen for the Treatment of Adults With Uncontrolled Hypertension (KARDINAL) Tonlamarsen, Placebo - Hypertension | Phase 2 | Completed | Kardigan, Inc. | 206 | 2025-04-10 | 2026-03-31 |
| Early Intracoronary N-Acetylcysteine During Primary PCI in STEMI: A Pilot Randomized Trial of Reperfusion Injury Biomarkers and Functional Recovery Antipac - STEMI - ST Elevation Myocardial Infarction (MI), Primary PCI - STEMI | Phase 2 | Completed | dr. Ahmad Yasa, Sp.JP, Subsp.K.I.(K), M.Kes, FIHA, FasCC, FA | 110 | 2025-04-01 | 2026-10-02 |
| A Trial to Assess the Efficacy and Safety of OTR4132-MD in Patients With Acute Ischemic Stroke OTR4132, Placebo - Endovascular Thrombectomy, Ischemic Cerebrovascular Accident | Phase 2 | Completed | Organ, Tissue, Regeneration, Repair and Replacement | 60 | 2025-03-14 | 2026-06-26 |
| To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU. Placebo drug ( normal saline ), neostigmine (reversal agent) - Tachycardia, Hypertension | Phase 1 / Phase 2 | Completed | Ziauddin University | 100 | 2025-03-12 | 2025-07-31 |
| A Study to Assess the Efficacy and Safety of Lorundrostat in Participants With Obstructive Sleep Apnea and Hypertension Lorundrostat, Placebo - Obstructive Sleep Apnea, Hypertension | Phase 2 | Completed | Mineralys Therapeutics Inc. | 48 | 2025-02-28 | 2026-08-21 |
| Impact of LLL and Aerobic Exercise on Peripheral Arterial Outcomes in Patients With Type 2 Diabetes aerobic exercise + low-level laser therapy, Aerobic exercise - Type 2 Diabetes Mellitus (T2DM) | Phase 2 | Completed | Nouran Hesham Slama Younis | 40 | 2025-02-20 | 2025-08-19 |
| Efficacy of Varenicline Tartrate in Treating Frequent Premature Ventricular Contractions Varenicline Tartrate Tablets, Placebo - Premature Ventricular Contraction (PVC) | Phase 2 | Completed | Yihan Chen | 116 | 2025-02-17 | 2025-11-19 |
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Multiple Myeloma (747) · Stroke (312) · Hypertension (274) · Coronary Artery Disease (198) · Neoplasms, Plasma Cell (176) · Lymphoma, Non-Hodgkin (172) · Leukemia, Lymphocytic, Chronic, B-Cell (168) · Waldenstrom Macroglobulinemia (152) · Ischemic Stroke (151) · Lymphoma, Follicular (146) · Hodgkin Disease (136) · Lymphoma (134) · Lymphoma, B-Cell, Marginal Zone (134) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (126) · Lymphoma, Mantle-Cell (122)
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Dexamethasone (232) · Cyclophosphamide (149) · Bortezomib (136) · Lenalidomide (130) · Melphalan (111) · Calcium Dobesilate (77) · Peripheral Blood Stem Cell Transplantation (71) · fludarabine phosphate (61) · Rituximab (57) · Filgrastim (56) · Mycophenolic Acid (52) · Thalidomide (49) · Aspirin (47) · Clopidogrel (46) · Busulfan (45)
Mayo Clinic (52) · Fred Hutchinson Cancer Center (48) · National Heart, Lung, and Blood Institute (NHLBI) (44) · National Cancer Institute (NCI) (43) · Novartis Pharmaceuticals (36) · Memorial Sloan Kettering Cancer Center (28) · GlaxoSmithKline (27) · M.D. Anderson Cancer Center (27) · Bayer (26) · Dana-Farber Cancer Institute (21) · University of Arkansas (21) · Boehringer Ingelheim (20) · US Department of Veterans Affairs (20) · Amgen (17) · Bristol-Myers Squibb (17)
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Brenda Sandmaier (8) · Marc Bosiers, MD (7)
PMID 37870112, PMID 32499241, PMID 33175411, PMID 36326435, PMID 24107737, PMID 27657681, PMID 30957581, PMID 35549810, PMID 21762873, PMID 22163120, PMID 22496083, PMID 31221778, PMID 33027067, PMID 33086312, PMID 33107592, PMID 33337539, PMID 35526057, PMID 35802393, PMID 36408587, PMID 38189593, PMID 40156952, PMID 41114449, PMID 42573020, PMID 18296121, PMID 18536865, PMID 20661232, PMID 21079055, PMID 21849262, PMID 22212857, PMID 22440499, PMID 22474060, PMID 22608107, PMID 22738918, PMID 22795280, PMID 23176611, PMID 24524452, PMID 25378424, PMID 25578927, PMID 25628469, PMID 25677596, PMID 25726502, PMID 26181891, PMID 26280447, PMID 26308596, PMID 26690712, PMID 27148802, PMID 27307294, PMID 29025767, PMID 29976553, PMID 30536810
P30CA015083 (30), 2017 (22), 2016 (20), 2015 (19), P30CA015704 (19), 2008 (18), 2014 (18), 2018 (16), 2009 (14), 2005 (12), 2019 (11), 2023 (11), P30CA006973 (10), U10CA032102 (8), 2004 (7)