43 completed, 10 unknown, 6 recruiting, 5 terminated. 31 Not applicable, 15 Phase 3, 9 Phase 2, 9 Phase 4, 2 Phase 1.
Follow Vaginal Atrophy: new trials by email Literature Review of Vaginal Atrophy trials Research Report on Vaginal Atrophy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV Vaginal estradiol tablets, Vaginal moisturizer - Menopausal Complaints, Vaginal Atrophy | Phase 4 | Not yet recruiting | Albert Einstein College of Medicine | 62 | 2026-09-01 | 2026-07-28 |
| F-GYN for Vaginal Dryness and Vulvovaginal Atrophy F-GYN Non-Crosslinked Hyaluronic Acid Injectable Gel, Standard Non-Hormonal Symptomatic Care - Atrophic Vaginitis, Atrophic Vulvovaginitis | Not applicable | Recruiting | Biovico Sp. z o.o. | 130 | 2026-07-24 | 2026-10-01 |
| Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial Laser Therapy, Sham Intervention, Questionnaire Administration - Vaginal Atrophy, Breast Carcinoma | Phase 3 | Recruiting | Alliance for Clinical Trials in Oncology | 250 | 2026-04-21 | 2026-10-19 |
| Compare Vaginal Estrogen and Platelet-rich Plasma Over Women With Genitourinary Syndrome of Menopause Vaginal estrogen supplement, Platelet-rich plasma injection - Menopause, Platelet-rich Plasma | Not yet recruiting | Mackay Memorial Hospital | 40 | 2025-12-01 | 2025-05-09 | |
| ASSIST-VLA: Assessment of Symptom-Specific Improvement in Diagnosed Vaginal Atrophy Following Laser Therapy 7-940 - Vaginal Atrophy, Atrophic Vaginitis | Phase 4 | Completed | Stratpharma AG | 11 | 2025-08-13 | 2026-07-20 |
| Hydration and Acceptability of the Genital and Skin Mucosa of a Vaginal Moisturizer in Menopausal Women 0.20% sodium hyaluronate gel - Vaginismus, Vaginal Atrophy | Phase 3 | Unknown | Biolab Sanus Farmaceutica | 45 | 2025-03-01 | 2024-08-21 |
| Postpartum Vaginal Estrogen for Breastfeeding Patients Estradiol, Vaginal Moisturizer - Breastfeeding, Postpartum Sexual Dysfunction | Phase 4 | Recruiting | University Hospitals Cleveland Medical Center | 100 | 2025-02-22 | 2026-07-23 |
| The Efficacy of Topical Vaginal Oxytocin Gel in Postmenopausal Women With Vulvovaginal Atrophy Oxytocin, Hydroxypropyl methylcellulose - Vaginal Atrophy, Genitourinary Syndrome of Menopause | Phase 3 | Unknown | Oxagon | 244 | 2024-09-01 | 2024-07-23 |
| Perceived Effectiveness of the Vaginal Moisturizer Investigational Product Under Normal Conditions of Use. vaginal moisturizer - Vaginal Atrophy | Not applicable | Completed | Herbarium Laboratorio Botanico Ltda | 45 | 2024-06-10 | 2024-11-18 |
| Effect of Local Estriol Treatment Before Vaginal Repair Surgery estriol cream - Pelvic Organ Prolapse, Pelvic Floor Disorders | Phase 3 | Active not recruiting | Hatice Tukenmez Kurnaz | 36 | 2024-04-01 | 2025-02-05 |
| PRP Injections for Genitourinary Syndrome of Menopause Injection of platelet-rich plasma, Injection of saline - PRP, Sexual Function Disturbances | Not applicable | Active not recruiting | Medstar Health Research Institute | 30 | 2024-03-01 | 2025-11-14 |
| VALOR: Vaginal Atrophy & Long-term Observation of Recovery 7-0940 - Atrophic Vaginitis, Vaginal Atrophy | Not applicable | Recruiting | Stratpharma AG | 2000 | 2023-10-30 | 2026-02-20 |
| Elastographic Improvement of Vaginal Atrophy Treated by Erbium Yag Laser Fotona Dynamis Er:YAG Laser System, Sham - Vaginal Atrophy, Dyspareunia | Not applicable | Completed | Istanbul University - Cerrahpasa | 20 | 2023-08-21 | 2025-04-30 |
| Clinical Performance and Safety of the VITA AV Clinical System VITA AV Clinical System - Vaginal Atrophy | Not applicable | Completed | AVeta Medical | 12 | 2023-04-13 | 2024-12-17 |
| Vaginal Estradiol Use in Pessary Care Estradiol vaginal cream - Pelvic Organ Prolapse, Urinary Incontinence | Early Phase 1 | Terminated | University of South Florida | 11 | 2022-12-29 | 2023-05-11 |
| Effects of Vaginal Oxytocin Gel on Vaginal Cytologic Parameters in Postmenopausal Woman Oxytocin, Placebo - Vaginal Atrophy, Oxytocin Gel | Phase 2 / Phase 3 | Terminated | Department of Medical Services Ministry of Public Health of Thailand | 6 | 2022-11-30 | 2023-08-31 |
| Laser Treatment of Genito-urinary Syndrome in Women Vaginal laser treatment, sham, laser system - Laser-Induced Scar, Breast Cancer | Not applicable | Withdrawn | Herning Hospital | 2022-10-01 | 2024-10-16 | |
| Low-level Laser Therapy for Genitourinary Syndromes and Stress Urinary Incontinence Low-level laser therapy - Vaginal Atrophy, Urinary Incontinence,Stress | Completed | National Taiwan University Hospital | 41 | 2022-09-30 | 2023-11-18 | |
| Clinical and Molecular Study to Evaluate the Effect of the Pixel CO2 Laser (FemiLiftTM) for the Treatment of Vulvo-Vaginal Atrophy Pixel CO2 Laser for the Treatment of Vulvo-Vaginal Atrophy (VVA) - Vulvar Atrophy, Vaginal Atrophy | Not applicable | Recruiting | Hillel Yaffe Medical Center | 20 | 2022-09-02 | 2025-06-17 |
| Clinical Trial of "Magic Gyno" Laser Device Laser treatment, Blood test, Clinical urine test - Female Urogenital Diseases, Urinary Incontinence | Not applicable | Completed | MeLSyTech, Ltd | 70 | 2022-08-05 | 2024-12-10 |
Showing 20 of 72. Sign in to see all of them.
Atrophic Vaginitis (12) · Dyspareunia (9) · Breast Neoplasms (6) · Pelvic Organ Prolapse (4) · Sexual Dysfunction, Physiological (4) · Urinary Incontinence (4) · Atrophy (3) · Female Urogenital Diseases (3) · Urinary Incontinence, Stress (3) · Vaginitis (3) · Aging, Premature (2) · Dysbiosis (2) · HIV Infections (2) · Pelvic Floor Disorders (2) · Urogenital Diseases (2)
Female Urogenital Diseases and Pregnancy Complications (33) · Urogenital Diseases (33) · Female Urogenital Diseases (30) · Genital Diseases (26) · Genital Diseases, Female (24) · Male Urogenital Diseases (18) · Pathological Conditions, Signs and Symptoms (18) · Vaginal Diseases (14) · Mental Disorders (11) · Signs and Symptoms (11) · Sexual Dysfunctions, Psychological (10) · Vaginitis (10) · Genital Diseases, Male (9) · Lower Urinary Tract Symptoms (9) · Urologic Diseases (9)
Dehydroepiandrosterone (7) · Estradiol (6) · Estriol (4) · Laser Therapy (4) · Oxytocin (3) · Vaginal Smears (3) · Estrogens, Conjugated (USP) (2) · Replens (2) · promestriene (2) · Biopsy (1) · Elasticity Imaging Techniques (1) · Hematologic Tests (1) · Hypromellose Derivatives (1) · Lasers (1) · Lasers, Gas (1)
EndoCeutics Inc. (5) · PepTonic Medical AB (4) · MeLSyTech, Ltd (3) · ITF Research Pharma, S.L.U. (2) · National and Kapodistrian University of Athens (2) · Stratpharma AG (2) · AVeta Medical (1) · Albert Einstein College of Medicine (1) · Alliance for Clinical Trials in Oncology (1) · Alma Lasers Inc. (1) · Aspen USA Inc (1) · Biolab Sanus Farmaceutica (1) · Bionovo (1) · Biovico Sp. z o.o. (1) · Bitop AG (1)
United States (28) · Canada (6) · Sweden (6) · Spain (5) · Brazil (4) · Russia (3) · Czechia (2) · Germany (2) · Greece (2) · Israel (2) · Italy (2) · Taiwan (2) · Turkey (Türkiye) (2) · Bulgaria (1) · China (1)
David F Archer, MD (3) · Kerry J Murphy, MD (2) · Stavros Athanasiou, Associate Proffesor (2) · Aino F Jonasson, M.D, PhD (1) · Aino Fianu Jonasson, MD Ass Prof (1) · Aino Fianu Jonasson, MD, PhD (1) · Alexandra N Garcia, MD (1) · Ali A Qureshi, MD (1) · Andrew F Hundley, MD (1) · Assem Anwar (1) · Aviva Preminger, MD (1) · Cemal Tamer Erel, Prof. (1) · Christine M Vaccaro, DO (1) · Cusan Leonello, MD Ph D (1) · David Archer, MD (1)
PMID 25968836, PMID 26972555, PMID 40709601, PMID 18351586, PMID 18598765, PMID 18799443, PMID 19424093, PMID 19436225, PMID 19436226, PMID 20459349, PMID 21244215, PMID 21422866, PMID 22914208, PMID 23954500, PMID 24774442, PMID 25491701, PMID 25511551, PMID 25559048, PMID 25734980, PMID 25771041, PMID 25961226, PMID 26291918, PMID 26509785, PMID 26517756, PMID 26597311, PMID 26634942, PMID 26725467, PMID 26731686, PMID 27997350, PMID 28364861, PMID 28539177, PMID 31157569, PMID 32329093, PMID 32459035, PMID 33534428, PMID 34291703, PMID 35236871, PMID 36787527, PMID 37431855, PMID 37619252, PMID 37650754, PMID 37963315, PMID 38583316, PMID 38714422, PMID 38860935, PMID 39566128, PMID 8694033
2014 (1), 2015 (1), 2019 (1), K23AG062400 (1), R01AG102277 (1), UG1CA189823 (1)