9 completed, 3 recruiting, 1 no longer available, 1 unknown. 6 Not applicable, 3 Phase 2, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 3, Recruiting 2, Unknown 1 |
| Phase 2 | 3 | Completed 2, Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Tourette Disorder: new trials by email Literature Review of Tourette Disorder trials Research Report on Tourette Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Integrating Exposure and Response Prevention and Habit Reversal Techniques to Treat a Tourettic Subtype of Obsessive-Compulsive Disorder (Tourettic OCD) Exposure and Response Prevention (ERP), Habit Reversal Training (HbRT, Psychoeducation and Supportive Intervention - Obsessive - Compulsive Disorder, Tic Disorder, Chronic Motor or Vocal | Not applicable | Recruiting | University College London Hospitals | 40 | 2026-07-08 | 2026-07-27 |
| Sensorimotor Integration in Patients With Tourette Syndrome Tourette Disorder, Sensory Gating | Completed | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | 60 | 2025-03-20 | 2025-12-18 | |
| Investigating Changes in Premonitory Urges During Habit Reversal Training for Tics Habit Reversal Training - Tics, Tourette Disorder | Not applicable | Recruiting | University of Utah | 6 | 2025-02-11 | 2025-05-28 |
| Serotonin Control of Impulsivity in Tourette Disorder Administration of a PET radiotracer - Tourette Disorder | Phase 2 | Recruiting | Hospices Civils de Lyon | 25 | 2024-09-24 | 2024-12-04 |
| Ecopipam Tablets to Study Tourette's Disorder in Children, Adolescents and Adults Ecopipam Hydrochloride - Tourette Disorder | Phase 3 | Completed | Emalex Biosciences Inc. | 216 | 2023-01-31 | 2026-06-12 |
| Online-Delivered Comprehensive Behavioral Intervention for Tics-Enhanced (CBIT-E) Comprehensive Behavioral Intervention for Tics - Enhanced (CBIT-E) - Persistent Tic Disorders, Tourette Disorder | Not applicable | Unknown | Marquette University | 30 | 2021-09-15 | 2021-10-08 |
| Evaluating the Efficacy and Safety of Yi-Gan San in Children and Adolescents With Tourette's Disorder Yigansan, Placebo - Tourette Disorder, Tic Disorders | Phase 2 | Completed | China Medical University Hospital | 38 | 2018-06-16 | 2023-04-27 |
| Augmentation of Brief Habit Reversal Training With D-cycloserine or Placebo D-cycloserine, Placebo - Tourette Disorder, Chronic Tic Disorder | Not applicable | Completed | University of California, Los Angeles | 20 | 2015-10-01 | 2019-04-25 |
| Dissemination of Comprehensive Behavioral Intervention for Tics (CBIT) to Occupational Therapists: A Feasibility Study OTs Trained and Deliver CBIT - Tourette Disorder, Chronic Tic Disorder | Not applicable | Completed | Weill Medical College of Cornell University | 13 | 2013-11-01 | 2019-09-20 |
| Guanfacine in Children With Tic Disorders placebo, extended-release guanfacine (Intuniv) - Tourette Disorder, Tourette Syndrome | Phase 4 | Completed | Yale University | 34 | 2012-04-01 | 2021-08-13 |
| Psychosocial Intervention for Young Children With Chronic Tics Comprehensive Behavioral Intervention for Tics (CBIT) - Tourette's Syndrome, Tourette's Disorder | Not applicable | Completed | Weill Medical College of Cornell University | 15 | 2012-01-20 | 2019-07-30 |
| Subthalamic Stimulation in Tourette's Syndrome STN DBS - Tourette's Syndrome, Tourette Syndrome | Phase 2 | Completed | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 10 | 2011-12-01 | 2016-02-23 |
| Neuropsychological Functioning Among Children With Tourret's Disorder and ADHD Tourette Disorder, Attention-Deficit/Hyperactivity Disorder | Completed | National Taiwan University Hospital | 120 | 2007-01-01 | 2012-11-14 | |
| Expanded Access Program for Treatment With Ecopipam for Tourette's Disorder ecopipam HCl ~2mg/kg/day - Tourettes Disorder, Tourette Disorder | No longer available | Emalex Biosciences Inc. | 2026-10-28 |
Tourette Syndrome (14) · Tic Disorders (4) · Tics (4) · Obsessive-Compulsive Disorder (2) · Attention Deficit Disorder with Hyperactivity (1) · Compulsive Personality Disorder (1) · Impulsive Behavior (1)
Basal Ganglia Diseases (14) · Brain Diseases (14) · Central Nervous System Diseases (14) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (14) · Genetic Diseases, Inborn (14) · Heredodegenerative Disorders, Nervous System (14) · Mental Disorders (14) · Movement Disorders (14) · Nervous System Diseases (14) · Neurodegenerative Diseases (14) · Neurodevelopmental Disorders (14) · Tic Disorders (10) · Dyskinesias (4) · Neurologic Manifestations (4) · Pathological Conditions, Signs and Symptoms (4)
Cycloserine (1) · Guanfacine (1)
Emalex Biosciences Inc. (2) · Weill Medical College of Cornell University (2) · China Medical University Hospital (1) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (1) · Hospices Civils de Lyon (1) · I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio (1) · Marquette University (1) · National Taiwan University Hospital (1) · University College London Hospitals (1) · University of California, Los Angeles (1) · University of Utah (1) · Yale University (1)
United States (7) · Italy (3) · France (2) · Taiwan (2) · Bulgaria (1) · Canada (1) · Denmark (1) · Germany (1) · Hungary (1) · Poland (1) · Romania (1) · Serbia (1) · Spain (1) · United Kingdom (1)
Shannon Bennett, PhD (2) · Barbara J Coffey, MD, MS (1) · Cheng-Hao Huang (1) · Jan Rowe, OT (1) · Joseph F McGuire, Ph.D. (1) · Lawrence D Scahill, MSN, PhD (1) · Luigi M Romito, MD, PhD (1) · Sarah Atkinson, MD (1) · Susan Shur-Fen Gau, MD, PhD (1) · Tanya Murphy, MD, MS (1) · Thomas Fernandez, MD (1)
2023 (1)