5 completed, 3 unknown. 8 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 8 | Completed 5, Unknown 3 |
Follow Thalassemia Major: new trials by email Literature Review of Thalassemia Major trials Research Report on Thalassemia Major
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Safety and Efficiency of Luspatercept in Chinese Adults With Transfusion Dependent β-thalassemia: a Real-world Study Luspatercept Injectable Product - Thalassemia Major, Transfusion-dependent Anemia | Phase 4 | Unknown | Sun Yat-sen University | 20 | 2022-07-01 | 2022-07-18 |
| Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major: A Multicenter, Prospective Clinical Study Busulfan, Cyclophosphamide, Fludarabine - Thalassemia Major | Phase 4 | Completed | First Affiliated Hospital of Guangxi Medical University | 823 | 2019-07-05 | 2024-08-09 |
| Impact of the Preparation Method of Red Cell Concentrates on Transfusion Indices in Thalassemic Patients Blood component A, Blood component B - Thalassemia Major | Phase 4 | Completed | Università degli Studi di Ferrara | 55 | 2018-05-14 | 2021-11-12 |
| Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major Busulfan, Cyclophosphamide, Fludarabine - Thalassemia Major | Phase 4 | Unknown | First Affiliated Hospital of Guangxi Medical University | 30 | 2017-04-01 | 2017-05-31 |
| The Effect of Vitamin D Supplementation on Calcium Excretion in Thalassemia: a Dose Response Study Vitamin D3, Placebo - Thalassemia Major | Phase 4 | Unknown | Weill Medical College of Cornell University | 40 | 2011-06-01 | 2011-04-19 |
| Pilot Study for Patients With Poor Response to Deferasirox Deferoxamine, Deferasirox, HIDA - Transfusion-dependent Hemachromatosis, Thalassemia Major | Phase 4 | Completed | Boston Children's Hospital | 15 | 2008-03-01 | 2024-02-12 |
| Efficacy Study in Removing Excess Iron From the Heart Ferriprox (deferiprone), Desferal (deferoxamine) - Thalassemia Major, Hemosiderosis | Phase 4 | Completed | ApoPharma | 60 | 2002-12-01 | 2016-01-05 |
| Efficacy Study of the Use of Sequential DFP-DFO Versus DFP Deferiprone (DFP) and Deferoxamine (DFO), Deferiprone (DFP) - Beta-Thalassemia, Thalassemia Major | Phase 4 | Completed | Azienda Ospedaliera V. Cervello | 213 | 2000-09-01 | 2008-08-13 |
beta-Thalassemia (8) · Thalassemia (3) · Anemia, Sickle Cell (1) · Hemochromatosis (1) · Hemosiderosis (1) · Hypercalciuria (1) · Iron Overload (1)
Anemia (8) · Anemia, Hemolytic (8) · Anemia, Hemolytic, Congenital (8) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (8) · Genetic Diseases, Inborn (8) · Hematologic Diseases (8) · Hemic and Lymphatic Diseases (8) · Hemoglobinopathies (8) · Thalassemia (5) · Iron Metabolism Disorders (1) · Metabolic Diseases (1) · Metabolism, Inborn Errors (1) · Metal Metabolism, Inborn Errors (1) · Nutritional and Metabolic Diseases (1) · Pathological Conditions, Signs and Symptoms (1)
Deferoxamine (3) · Busulfan (2) · Cyclophosphamide (2) · Deferiprone (2) · Influenza Vaccines (2) · Methotrexate (2) · Mycophenolic Acid (2) · Tacrolimus (2) · fludarabine (2) · thymoglobulin (2) · Basiliximab (1) · Cholecalciferol (1) · Cyclosporine (1) · Deferasirox (1) · Isoflurophate (1)
First Affiliated Hospital of Guangxi Medical University (2) · ApoPharma (1) · Azienda Ospedaliera V. Cervello (1) · Boston Children's Hospital (1) · Sun Yat-sen University (1) · Università degli Studi di Ferrara (1) · Weill Medical College of Cornell University (1)
China (3) · Italy (3) · United States (2) · Greece (1)
Yongrong Lai, MD (2) · Antonio Piga, M.D. (1) · Deborah Chirnomas, MD (1) · Jianpei Fang, Dr. (1) · Maria Rita Gamberini, MD (1) · Maria Vogiatzi, MD (1) · Markissia Karagiorga, M.D. (1) · Renzo Galanello, M.D. (1) · Vassilis Ladis, M.D. (1)