3 terminated, 2 completed, 1 recruiting. 3 Phase 1, 2 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 1, Recruiting 1, Terminated 1 |
| Not applicable | 2 | Completed 1, Terminated 1 |
| Phase 2 | 1 | Terminated 1 |
Follow Stage IVA Vaginal Cancer AJCC v8: new trials by email Literature Review of Stage IVA Vaginal Cancer AJCC v8 trials Research Report on Stage IVA Vaginal Cancer AJCC v8
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sexual Health Counseling Intervention During Radiation Therapy in Improving Quality of Life for Women With Gynecologic Cancer Counseling, Quality-of-Life Assessment, Questionnaire Administration - Malignant Female Reproductive System Neoplasm, Stage I Cervical Cancer AJCC v8 | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 4 | 2021-05-20 | 2024-05-09 |
| Talazoparib and Radiation Therapy in Treating Patients With Locally Recurrent Gynecologic Cancers Quality-of-Life Assessment, Radiation Therapy, Talazoparib - Malignant Female Reproductive System Neoplasm, Recurrent Cervical Carcinoma | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 24 | 2019-09-26 | 2026-03-11 |
| DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine MEDI0457, Durvalumab - Human Papillomavirus-16 Positive, Human Papillomavirus-18 Positive | Phase 2 | Terminated | M.D. Anderson Cancer Center | 41 | 2018-11-14 | 2024-07-09 |
| MRI-Guided Brachytherapy in Treating Participants With HPV-Associated Stage IB2-IVA Cervical or Stage II-IVA Vaginal Cancer Internal Radiation Therapy, Magnetic Resonance Imaging - Human Papillomavirus-Related Carcinoma, Human Papillomavirus-Related Cervical Carcinoma | Phase 1 | Terminated | M.D. Anderson Cancer Center | 26 | 2018-08-03 | 2026-09-15 |
| Stereotactic Body Radiation Therapy, Tremelimumab and Durvalumab in Treating Participants With Recurrent or Metastatic Cervical, Vaginal, or Vulvar Cancers Durvalumab, Laboratory Biomarker Analysis, Stereotactic Radiosurgery - Advanced Cervical Adenocarcinoma, Advanced Vaginal Carcinoma | Phase 1 | Completed | M.D. Anderson Cancer Center | 20 | 2018-07-18 | 2023-09-13 |
| Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer Biospecimen Collection, Laboratory Biomarker Analysis - Cervical Adenocarcinoma, Cervical Adenocarcinoma In Situ | Not applicable | Terminated | M.D. Anderson Cancer Center | 409 | 2014-10-27 | 2025-07-14 |
Uterine Cervical Neoplasms (6) · Vaginal Neoplasms (6) · Vulvar Neoplasms (4) · Anal Canal Carcinoma (1) · Anus Neoplasms (1) · Endometrial Neoplasms (1) · Fallopian Tube Neoplasms (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Ovarian Neoplasms (1) · Penile Neoplasms (1) · Recurrence (1) · Uterine Cervical Dysplasia (1)
Female Urogenital Diseases (6) · Female Urogenital Diseases and Pregnancy Complications (6) · Genital Diseases (6) · Genital Diseases, Female (6) · Genital Neoplasms, Female (6) · Neoplasms by Site (6) · Urogenital Diseases (6) · Urogenital Neoplasms (6) · Uterine Cervical Diseases (6) · Uterine Diseases (6) · Uterine Neoplasms (6) · Vaginal Diseases (6) · Neoplasms (5) · Vulvar Diseases (4) · Adnexal Diseases (1)
Disulfides (2) · Immunoglobulin G (2) · durvalumab (2) · Brachytherapy (1) · Counseling (1) · MEDI0457 (1) · Magnetic Resonance Spectroscopy (1) · Radiation (1) · Radiosurgery (1) · Radiotherapy (1) · VGX-3100 (1) · rocakinogene sifuplasmid (1) · talazoparib (1) · tremelimumab (1)
M.D. Anderson Cancer Center (5) · Ohio State University Comprehensive Cancer Center (1)
United States (6)
Lilie L Lin (2) · Allison M Quick, MD (1) · Ann H Klopp (1) · Kathleen Schmeler (1) · Michael M Frumovitz (1)
P30CA016672 (1)