11 completed, 6 active not recruiting, 2 recruiting, 1 suspended. 9 Phase 2, 5 Not applicable, 3 Phase 3, 2 Early Phase 1, 1 Phase 1.
Follow Stage I Breast Cancer AJCC v7: new trials by email Literature Review of Stage I Breast Cancer AJCC v7 trials Research Report on Stage I Breast Cancer AJCC v7
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection Questionnaire Administration, Biospecimen Collection - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Recruiting | Alliance for Clinical Trials in Oncology | 2000 | 2022-08-18 | 2026-10-02 | |
| Patient Reported Outcomes, Smart Pill Bottle and Teleheath for Endocrine Therapy Adherence Telemedicine, Best Practice, Questionnaire Administration - Stage 0 Breast Cancer AJCC v6 and v7, Stage I Breast Cancer AJCC v7 | Not applicable | Completed | Thomas Jefferson University | 305 | 2019-07-31 | 2026-02-05 |
| SCOUT Reflector for Tagging Lymph Nodes for Targeted Removal in Patients With Breast Cancer Implanted Medical Device, Therapeutic Conventional Surgery - Positive Axillary Lymph Node, Stage 0 Breast Cancer AJCC v6 and v7 | Early Phase 1 | Completed | Jonsson Comprehensive Cancer Center | 27 | 2019-04-07 | 2023-01-17 |
| Ginseng in Decreasing Cancer-Related Fatigue After Treatment in Cancer Survivors American Ginseng, Laboratory Biomarker Analysis, Placebo - Cancer Survivor, Stage I Breast Cancer AJCC v7 | Early Phase 1 | Completed | Mayo Clinic | 2 | 2019-03-01 | 2023-01-05 |
| Phase I Trial of Endoxifen Gel Versus Placebo in Women Undergoing Breast Surgery Endoxifen Hydrochloride, Placebo Administration, Questionnaire Administration - Breast Carcinoma In Situ, Breast Ductal Carcinoma In Situ | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 32 | 2018-10-31 | 2026-09-02 |
| The Effect of Simvastatin on Breast Cancer Cell Growth in Women With Stage I-II Breast Cancer Laboratory Biomarker Analysis, Simvastatin - Invasive Breast Carcinoma, Stage I Breast Cancer AJCC v7 | Phase 2 | Completed | Michael Simon | 24 | 2018-03-09 | 2023-08-01 |
| Hypofractionated Radiation Therapy in Preventing Recurrence in Patients With Breast Cancer After Surgery Hypofractionated Radiation Therapy, Quality-of-Life Assessment, Radiation Therapy - Stage I Breast Cancer AJCC v7, Stage IA Breast Cancer AJCC v7 | Phase 3 | Completed | Mayo Clinic | 107 | 2018-02-07 | 2024-05-02 |
| Kindness Interventions in Enhancing Well-Being in Breast Cancer Survivors Behavioral Intervention, Questionnaire Administration - Cancer Survivor, Stage 0 Breast Cancer AJCC v6 and v7 | Not applicable | Completed | Jonsson Comprehensive Cancer Center | 133 | 2017-07-11 | 2020-07-24 |
| Hypofractionated Partial Breast Irradiation in Treating Patients With Early Stage Breast Cancer Laboratory Biomarker Analysis, Partial Breast Irradiation, Questionnaire Administration - Ductal Breast Carcinoma In Situ, Early-Stage Breast Carcinoma | Phase 2 / Phase 3 | Suspended | M.D. Anderson Cancer Center | 928 | 2017-03-06 | 2026-09-14 |
| Hypofractionated vs. Conventional Regional Nodal Radiation Therapy for Patients With Invasive Breast Cancer Hypofractionated Radiation Therapy, Laboratory Biomarker Analysis, Quality-of-Life Assessment - Invasive Breast Carcinoma, Stage I Breast Cancer AJCC v7 | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 805 | 2017-02-23 | 2026-07-15 |
| Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy Undergo EBRT, Laboratory Biomarker Analysis, Quality-of-Life Assessment - Estrogen Receptor Negative, HER2 Positive Breast Carcinoma | Not applicable | Recruiting | M.D. Anderson Cancer Center | 120 | 2017-01-20 | 2026-09-25 |
| Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer Biospecimen Collection, Laboratory Biomarker Analysis, Patient Observation - Breast Carcinoma In Situ, Invasive Breast Carcinoma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 1195 | 2017-01-18 | 2026-10-26 |
| Alternative Dosing of Exemestane Before Surgery in Treating Postmenopausal Patients With Stage 0-II Estrogen Positive Breast Cancer Exemestane, Laboratory Biomarker Analysis, Pharmacological Study - Stage 0 Breast Cancer AJCC v6 and v7, Stage I Breast Cancer AJCC v7 | Phase 2 | Completed | National Cancer Institute (NCI) | 180 | 2016-12-06 | 2023-08-22 |
| Women's MoonShot: Neoadjuvant Treatment With PaCT for Patients With Locally Advanced TNBC Carboplatin, Paclitaxel, Panitumumab - Stage I Breast Cancer AJCC v7, Stage IA Breast Cancer AJCC v7 | Phase 2 | Completed | M.D. Anderson Cancer Center | 43 | 2016-11-03 | 2025-11-06 |
| Enzalutamide and Paclitaxel Before Surgery in Treating Patients With Stage I-III Androgen Receptor-Positive Triple-Negative Breast Cancer Axillary Lymph Node Dissection, Enzalutamide, Laboratory Biomarker Analysis - Invasive Breast Carcinoma, Stage I Breast Cancer AJCC v7 | Phase 2 | Completed | M.D. Anderson Cancer Center | 24 | 2016-09-22 | 2026-05-12 |
| Electroacupuncture Therapy in Reducing Chronic Pain in Patients After Breast Cancer Treatment Electroacupuncture Therapy, Laboratory Biomarker Analysis, Quality-of-Life Assessment - Stage I Breast Cancer AJCC v7, Stage IA Breast Cancer AJCC v7 | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 111 | 2016-09-13 | 2026-10-09 |
| Cyclophosphamide, Paclitaxel, and Trastuzumab in Treating Stage I-II HER2/Neu Positive Breast Cancer After Surgery Cyclophosphamide, Laboratory Biomarker Analysis, Paclitaxel - HER2 Positive Breast Carcinoma, Stage I Breast Cancer AJCC v7 | Phase 2 | Completed | University of Nebraska | 20 | 2015-12-11 | 2026-07-30 |
| Molecular Testing and Imaging in Improving Response in Patients With Stage I-III Triple-Negative Breast Cancer Receiving Chemotherapy MDACC Breast Moonshot Initiative Chemotherapy, Immunotherapy, Laboratory Biomarker Analysis - Invasive Breast Carcinoma, Stage I Breast Cancer AJCC v7 | Not applicable | Active not recruiting | M.D. Anderson Cancer Center | 798 | 2015-11-09 | 2026-07-15 |
| Sensorimotor Rehabilitation Program in Improving Quality of Life in Patients With Early Stage Breast Cancer Educational Intervention, Exercise Intervention, Quality-of-Life Assessment - Peripheral Neuropathy, Stage I Breast Cancer AJCC v7 | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 36 | 2015-07-02 | 2022-10-12 |
| Radiation Therapy in Treating Patients With Stage 0-II Breast Cancer Accelerated Partial Breast Irradiation, Proton Beam Radiation Therapy, Quality-of-Life Assessment - Breast Adenocarcinoma, Ductal Breast Carcinoma In Situ | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 200 | 2010-11-15 | 2026-05-01 |
Breast Neoplasms (20) · Breast Carcinoma In Situ (8) · Triple Negative Breast Neoplasms (5) · Carcinoma, Intraductal, Noninfiltrating (3) · Carcinoma, Renal Cell (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Esophageal Neoplasms (1) · Hematologic Neoplasms (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Leukemia, Myeloid, Acute (1) · Lung Neoplasms (1) · Melanoma (1) · Peripheral Nervous System Diseases (1)
Breast Diseases (20) · Neoplasms (20) · Neoplasms by Site (20) · Skin Diseases (20) · Skin and Connective Tissue Diseases (20) · Carcinoma (9) · Neoplasms by Histologic Type (9) · Neoplasms, Glandular and Epithelial (9) · Carcinoma in Situ (8) · Adenocarcinoma (4) · Neoplasms, Ductal, Lobular, and Medullary (3) · Colonic Diseases (2) · Digestive System Diseases (2) · Digestive System Neoplasms (2) · Gastrointestinal Diseases (2)
Paclitaxel (3) · Radiation (3) · Radiotherapy (3) · Taxes (3) · Behavior Therapy (2) · Early Intervention, Educational (2) · Educational Status (2) · Methods (2) · Radiation Dose Hypofractionation (2) · Sentinel Lymph Node Biopsy (2) · Adjuvants, Immunologic (1) · Asian ginseng (1) · Carboplatin (1) · Cyclophosphamide (1) · Drug Therapy (1)
M.D. Anderson Cancer Center (8) · National Cancer Institute (NCI) (3) · Jonsson Comprehensive Cancer Center (2) · Mayo Clinic (2) · Alliance for Clinical Trials in Oncology (1) · Michael Simon (1) · Ohio State University Comprehensive Cancer Center (1) · Thomas Jefferson University (1) · University of Nebraska (1)
United States (20) · Canada (1) · Italy (1) · Puerto Rico (1)
Clinton Yam (3) · Amulya Yellala, MD (1) · Amy Darragh, PhD, OTR/L (1) · Benjamin D Smith (1) · Bernardo Bonanni (1) · Carlos Vargas (1) · Henry M Kuerer (1) · Jennifer Baker, MD (1) · Julienne Bower (1) · Karen Hoffman, MD (1) · Lajos Pusztai (1) · Lorenzo Cohen (1) · Marie Wood, MD (1) · Maysa Abu-Khaaf, MD (1) · Melissa Mitchell, MD (1)
PMID 33587350, PMID 34253579, PMID 34652548, PMID 35507014, PMID 35617923, PMID 35914239, PMID 36216274, PMID 36306810, PMID 36951827, PMID 37505106, PMID 37547448, PMID 37707811, PMID 37914139, PMID 38484209, PMID 38578640, PMID 39110531, PMID 39356138, PMID 39503605, PMID 39558017, PMID 40152443, PMID 40366003, PMID 41499420, PMID 42093035
P30CA016672 (2), N01CN00034 (1), N01CN00035 (1), P30CA022453 (1), P30CA036727 (1), P30CA060553 (1), U10CA180888 (1), UG1CA189823 (1)