7 active not recruiting, 5 withdrawn, 4 not yet recruiting, 4 recruiting. 12 Phase 2, 11 Phase 1, 5 Not applicable, 2 Phase 3.
Follow Adjuvants, Immunologic: new trials by email Literature Review of Adjuvants, Immunologic trials Research Report on Adjuvants, Immunologic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing Repeat Radiation Therapy for Recurrent Non-small Cell Lung Cancer Biospecimen Collection, Computed Tomography, Immunotherapy - Locally Recurrent Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8 | Phase 2 | Not yet recruiting | NRG Oncology | 138 | 2026-12-18 | 2026-09-23 |
| Multiple Adjunct Therapies to Improve Immunotherapy Treatment in Patients With Locally Advanced or Metastatic Melanoma or Advanced Hepatocellular Cancer Biospecimen Collection, Cholecalciferol, Computed Tomography - Advanced Hepatocellular Carcinoma, Advanced Melanoma | Phase 2 | Not yet recruiting | University of Southern California | 46 | 2026-11-01 | 2026-09-23 |
| A Phase II Study of TT-01488 Tablets in Combination With Anti-CD20 Monoclonal Antibody Therapy in Patients With Mantle Cell Lymphoma TT-01488 Tablets, Rituximab, Immunomodulatory Agent - Mantle Cell Lymphoma (MCL) | Phase 2 | Not yet recruiting | TransThera Sciences (Nanjing), Inc. | 188 | 2026-10-10 | 2026-10-02 |
| A Trial on the Treatment of Bronchial Asthma With Budesonide Formoterol Combined With Immune Modulators (Staphylococcus and Neisseria Tablets) Budesonide Formoterol, Placebo, Immune Modulators (Staphylococcus and Neisseria Tablets) - Bronchial Asthma | Phase 3 | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 198 | 2025-06-20 | 2025-06-05 |
| Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer Biopsy, Biospecimen Collection, Bone Scan - Breast Carcinoma, Colorectal Carcinoma | Phase 1 | Active not recruiting | City of Hope Medical Center | 24 | 2025-05-27 | 2026-10-05 |
| Grid Radiation Therapy for the Treatment of Stage IV Non-Small Cell Lung Cancer Biospecimen Collection, Computed Tomography, Immunotherapy - Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8 | Phase 2 | Active not recruiting | Mayo Clinic | 3 | 2024-11-14 | 2026-10-15 |
| CART-BCMA/CS1 in Treating Patients With Relapsed or Refractory Multiple Myeloma Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography - Recurrent Multiple Myeloma, Refractory Multiple Myeloma | Phase 1 | Withdrawn | Jonsson Comprehensive Cancer Center | 2024-03-28 | 2024-05-01 | |
| Radiotherapy Combined With ICIs as Treatment for LA-NSCLC After Failing Induction Immunochemotherapy radiotherapy, Platinum-Based Drug, Immunotherapy - Non-small Cell Lung Cancer Stage III | Phase 3 | Unknown | Zhejiang Cancer Hospital | 105 | 2023-09-15 | 2023-09-13 |
| Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria) Immunotherapy, Stereotactic Radiosurgery, Vertebroplasty - Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm | Not applicable | Recruiting | Ohio State University Comprehensive Cancer Center | 200 | 2023-03-27 | 2026-04-09 |
| Multiple Myeloma Outcomes Based on Maintenance Therapy Post Autologous Stem Cell Transplant Autologous Stem Cell Transplant, Immunomodulatory Agent, Proteasome Inhibitor - Multiple Myeloma | Active not recruiting | H. Lee Moffitt Cancer Center and Research Institute | 69 | 2022-04-20 | 2026-03-02 | |
| Neoantigen Vaccine in Esophagus Cancer Patients Following Neoadjuvant Therapy and Surgical Resection iNeo-Vac-P01, GM-CSF - Resectable Esophageal Cancer | Phase 1 | Active not recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 27 | 2021-12-02 | 2025-12-02 |
| Stereotactic Body Radiation Therapy With Immunotherapy for the Treatment of Mesothelioma Immunotherapy, Quality-of-Life Assessment, Stereotactic Body Radiation Therapy - Pleural Mesothelial Neoplasm | Phase 1 | Completed | Mayo Clinic | 20 | 2021-07-12 | 2026-07-08 |
| Personalized Neoantigen Vaccine in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy iNeo-Vac-P01, GM-CSF - Resectable Pancreatic Cancer | Phase 1 | Unknown | Zhejiang Provincial People's Hospital | 20 | 2021-03-30 | 2021-11-16 |
| Clinical Study of a Personalized Neoantigen Cancer Vaccine Combined With Anti-PD-1 and RFA in Patients With Solid Tumors iNeo-Vac-P01, GM-CSF, PD-1 - Advanced Malignant Solid Tumor | Phase 1 | Unknown | Sir Run Run Shaw Hospital | 30 | 2020-09-03 | 2021-04-28 |
| Nodal Radiation Therapy for Sentinel Lymph Node Positive Melanoma Immunotherapy, Quality-of-Life Assessment, Radiation Therapy - Melanoma | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 168 | 2020-08-07 | 2026-08-10 |
| Cryoablation for the Treatment of Metastatic Cancer Core Biopsy, Cryosurgery, Immunotherapeutic Agent - Metastatic Malignant Neoplasm | Not applicable | Active not recruiting | M.D. Anderson Cancer Center | 15 | 2019-12-23 | 2026-08-06 |
| PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer Positron Emission Tomography, Computed Tomography, Chemotherapy - Metastatic Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma | Not applicable | Recruiting | University of Washington | 80 | 2019-09-26 | 2026-08-06 |
| Prospective Collection of Tumor Biopsy and Plasma Samples From Cancer Patients Treated With Molecular Targeted Therapies or Immunotherapy Immunotherapeutic Agent, Molecular Target - Cancer | Not applicable | Active not recruiting | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 200 | 2018-07-11 | 2023-12-11 |
| Targeted Therapy in Treating Patients With Incurable Non-Small Cell Lung Cancer With Genetic Mutations Chemotherapy, Immunotherapy, Laboratory Biomarker Analysis - EGFR Activating Mutation, Recurrent Non-Small Cell Lung Carcinoma | Phase 2 | Terminated | Wake Forest University Health Sciences | 19 | 2017-03-10 | 2024-06-28 |
| A Toll-like Receptor Agonist as an Adjuvant to Tumor Associated Antigens (TAA) Mixed With Montanide ISA-51 VG With Bevacizumab for Patients With Recurrent Glioblastoma Bevacizumab, Peptide Vaccine, Poly-ICLC as immune adjuvant - Glioblastoma, Glioma | Phase 2 | Withdrawn | NYU Langone Health | 2016-11-01 | 2020-01-13 |
Showing 20 of 31. Sign in to see all of them.
Carcinoma, Non-Small-Cell Lung (4) · Glioblastoma (4) · Lung Neoplasms (4) · Glioma (3) · Melanoma (3) · Multiple Myeloma (3) · Neoplasms (3) · Astrocytoma (2) · Brain Diseases (2) · Brain Neoplasms (2) · Breast Neoplasms (2) · Central Nervous System Diseases (2) · Central Nervous System Neoplasms (2) · Lymphoma, Mantle-Cell (2) · Nervous System Diseases (2)
M.D. Anderson Cancer Center (3) · TVAX Biomedical (3) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (2) · Mayo Clinic (2) · Barbara Ann Karmanos Cancer Institute (1) · Celgene (1) · City of Hope Medical Center (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Institut Bergonié (1) · Jonsson Comprehensive Cancer Center (1) · NRG Oncology (1) · NYU Langone Health (1) · National Cancer Institute (NCI) (1) · Ohio State University Comprehensive Cancer Center (1) · Radiation Therapy Oncology Group (1)
United States (19) · China (6) · Belgium (2) · France (2) · Canada (1) · Germany (1) · Greece (1) · Spain (1)
Alda L Tam (1) · Axel Le Cesne, MD/PhD (1) · Clinton Yam (1) · Dawn Owen, MD, PhD (1) · Devarati Mitra (1) · Diana Hanna (1) · Doris Hansen, MD (1) · Dukagjin M Blakaj, MD (1) · Gary Wood, Ph.D. (1) · Jean-Yves Blay, MD/PhD (1) · Jeffrey Y Wong (1) · Lei Deng, MD (1) · Maud Toulmonde, MD (1)
PMID 24563870, PMID 24567518, PMID 26095785, PMID 28391775, PMID 29117335, PMID 34253579, PMID 35507014, PMID 35914239, PMID 37505106, PMID 37547448, PMID 38484209, PMID 39503605, PMID 39558017, PMID 42093035, PMID 42687919
P30CA012197 (1), P30CA014089 (1), P30CA016672 (1), P30CA033572 (1), R01CA258997 (1), R01CA283603 (1), U10CA180868 (1)