4 completed, 3 recruiting, 2 active not recruiting, 2 unknown. 3 Not applicable, 3 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 2, Unknown 1 |
| Phase 2 | 3 | Not yet recruiting 1, Recruiting 1, Withdrawn 1 |
| Phase 3 | 2 | Active not recruiting 2 |
| Phase 1 | 1 | Recruiting 1 |
Follow Spinocerebellar Ataxia Type 1: new trials by email Literature Review of Spinocerebellar Ataxia Type 1 trials Research Report on Spinocerebellar Ataxia Type 1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-SA) for Patients With Spinocerebellar Ataxia Intravenous infusion, Intrathecal injection, umbilical cord mesenchymal stem cell - Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2 | Phase 2 | Not yet recruiting | Sclnow Biotechnology Co., Ltd. | 45 | 2026-12-31 | 2026-04-23 |
| A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD VO659 - Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 3 | Phase 1 / Phase 2 | Recruiting | Vico Therapeutics B. V. | 68 | 2023-02-14 | 2026-08-19 |
| Priming Motor Learning Through Exercise in People With Spinocerebellar Ataxia High-Intensity Aerobic Exercise Prior to Balance Training, Low-Intensity Exercise Prior to Balance Training - Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2 | Not applicable | Unknown | Teachers College, Columbia University | 20 | 2023-02-06 | 2024-05-03 |
| Study of CAD-1883 for Spinocerebellar Ataxia CAD-1883, Placebos - Spinocerebellar Ataxias, Spinocerebellar Ataxia Type 1 | Phase 2 | Withdrawn | Cadent Therapeutics | 2021-06-01 | 2021-04-08 | |
| Instrumented Data Exchange for Ataxia Study Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2 | Completed | University of Chicago | 128 | 2019-06-01 | 2024-08-05 | |
| Troriluzole in Adult Participants With Spinocerebellar Ataxia troriluzole, Placebo - Spinocerebellar Ataxias, Spinocerebellar Ataxia Type 1 | Phase 3 | Active not recruiting | Biohaven Pharmaceuticals, Inc. | 299 | 2019-03-08 | 2026-06-24 |
| Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia Anodal cerebellar and cathodal spinal tDCS, Sham cerebellar and sham spinal tDCS - Ataxia, Spinocerebellar Ataxias | Not applicable | Completed | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | 61 | 2018-12-01 | 2021-03-19 |
| Clinical Trial Readiness for SCA1 and SCA3 Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia 3 | Unknown | The Methodist Hospital Research Institute | 200 | 2018-08-16 | 2022-01-19 | |
| Open Pilot Trial of BHV-4157 BHV-4157 - Spinocerebellar Ataxias, Spinocerebellar Ataxia Type 1 | Phase 3 | Active not recruiting | University of California, Los Angeles | 24 | 2017-12-15 | 2024-05-09 |
| Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative Ataxia Anodal cerebellar and cathodal spinal tDCS, Sham cerebellar and sham spinal tDCS - Ataxia, Cerebellar, Cerebellar Ataxia | Not applicable | Completed | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | 21 | 2017-02-06 | 2020-03-03 |
| Biomarkers in Autosomal Dominant Cerebellar Ataxia metabolic and imaging biomarkers in SCA1,2,3 and 7 patients - Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2 | Completed | Assistance Publique - Hôpitaux de Paris | 102 | 2011-11-01 | 2019-09-06 | |
| Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford Rare Disorders, Undiagnosed Disorders | Recruiting | Sanford Health | 20000 | 2010-07-01 | 2026-10-28 | |
| Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias Genetic Testing, Blood Collection, Magnetic Resonance Imaging (MRI) Scan - Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2 | Recruiting | Lauren Moore | 1400 | 2010-04-01 | 2026-08-03 |
Spinocerebellar Ataxias (13) · Machado-Joseph Disease (12) · Ataxia (5) · Spinocerebellar Ataxia 10 (4) · Spinocerebellar ataxia 8 (4) · Friedreich Ataxia (3) · Multiple System Atrophy (3) · Spinocerebellar Degenerations (3) · Spinocerebellar ataxia, autosomal recessive 1 (3) · Cerebellar Ataxia (2) · Episodic Ataxia, Type 7 (2) · Olivopontocerebellar Atrophy V (2) · Spinocerebellar ataxia, autosomal recessive 3 (2) · 3-Methylglutaconic Aciduria, Type V (1) · Achalasia Addisonianism Alacrimia syndrome (1)
Brain Diseases (13) · Central Nervous System Diseases (13) · Cerebellar Diseases (13) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (13) · Dyskinesias (13) · Genetic Diseases, Inborn (13) · Heredodegenerative Disorders, Nervous System (13) · Nervous System Diseases (13) · Neurodegenerative Diseases (13) · Neurologic Manifestations (13) · Spinal Cord Diseases (13) · Cerebellar Ataxia (11) · Spinocerebellar Degenerations (10) · Ataxia (8) · Pathological Conditions, Signs and Symptoms (6)
Blood Specimen Collection (1) · Genetic Testing (1) · Infusions, Intravenous (1) · Injections, Spinal (1) · Magnetic Resonance Spectroscopy (1) · Metabolic Networks and Pathways (1) · Surveys and Questionnaires (1)
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (2) · Assistance Publique - Hôpitaux de Paris (1) · Biohaven Pharmaceuticals, Inc. (1) · Cadent Therapeutics (1) · Lauren Moore (1) · Sanford Health (1) · Sclnow Biotechnology Co., Ltd. (1) · Teachers College, Columbia University (1) · The Methodist Hospital Research Institute (1) · University of California, Los Angeles (1) · University of Chicago (1) · Vico Therapeutics B. V. (1)
United States (8) · France (2) · Italy (2) · Canada (1) · China (1) · Denmark (1) · Germany (1) · Israel (1) · Netherlands (1) · United Kingdom (1)
Alberto Benussi, MD (2) · Barbara Borroni, MD (2) · Vikram Shakkottai, MD, PhD (2) · Alexandra Durr, MD, PhD (1) · Ali G Hamedani, MD, PhD (1) · Chelsea E Macpherson, DPT (1) · Chiadikaobi Onyike, MD (1) · Christopher Gomez, MD, PhD (1) · Eva-Maria Ratai, MD (1) · George Wilmot, MD, PhD (1) · Gulin Oz, MD (1) · Hank Paulson, MD, PhD (1) · Haris I Sair, MD (1)
PMID 25449974, PMID 25773989, PMID 26644294, PMID 26943780, PMID 27848087, PMID 29057148, PMID 29089256, PMID 29106465, PMID 29922574, PMID 30135258, PMID 32982927, PMID 33636389, PMID 33951232, PMID 34115419, PMID 35962273, PMID 36797067, PMID 38489195, PMID 38615323, PMID 38814532, PMID 39806095, PMID 40665587, PMID 40679685, PMID 41445681, PMID 42301528