10 completed. 10 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 10 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow Spinal Cord Neoplasms: new trials by email Literature Review of Spinal Cord Neoplasms trials Research Report on Spinal Cord Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms. S-ketamine and pregabalin, Normal saline and placebo capsule - Esketamine, Pregabalin | Phase 2 / Phase 3 | Completed | Beijing Tiantan Hospital | 90 | 2021-12-01 | 2023-07-06 |
| Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System tozuleristide, Canvas imaging system, Surgical resection of tumor - Central Nervous System Tumor | Phase 2 | Completed | John Yu | 50 | 2021-09-30 | 2026-07-10 |
| Carboplatin and Bevacizumab for Recurrent Ependymoma Carboplatin, Bevacizumab - Ependymoma, Anaplastic Ependymoma | Phase 2 | Completed | National Cancer Institute (NCI) | 35 | 2011-04-27 | 2025-08-05 |
| Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma Bevacizumab, Temozolomide, Vorinostat - Brain Stem Glioma, Cerebral Astrocytoma | Phase 2 / Phase 3 | Completed | National Cancer Institute (NCI) | 101 | 2011-01-26 | 2024-02-20 |
| Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma Temozolomide, Lapatinib - Brain Tumors, Spinal Cord Tumors | Phase 2 | Completed | National Institutes of Health Clinical Center (CC) | 58 | 2009-01-01 | 2019-03-22 |
| Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma Bevacizumab, Fludeoxyglucose F-18, Irinotecan Hydrochloride - Childhood Cerebral Anaplastic Astrocytoma, Childhood Oligodendroglioma | Phase 2 | Completed | National Cancer Institute (NCI) | 97 | 2006-08-01 | 2017-11-28 |
| Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas Laboratory Biomarker Analysis, Lomustine, Radiation Therapy - Anaplastic Astrocytoma, Central Nervous System Neoplasm | Phase 2 | Completed | Children's Oncology Group | 118 | 2005-03-21 | 2023-02-15 |
| Erlotinib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Glioma Erlotinib hydrochloride - Brain and Central Nervous System Tumors | Phase 1 / Phase 2 | Completed | St. Jude Children's Research Hospital | 62 | 2005-03-01 | 2015-12-04 |
| Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment cyproheptadine hydrochloride, megestrol acetate - Brain Tumor, Central Nervous System Tumors | Phase 2 | Completed | University of South Florida | 70 | 2003-06-01 | 2014-02-03 |
| Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma temozolomide, adjuvant therapy, radiation therapy - Brain and Central Nervous System Tumors | Phase 2 | Completed | Children's Oncology Group | 170 | 2002-12-01 | 2014-02-21 |
Astrocytoma (6) · Central Nervous System Neoplasms (5) · Brain Neoplasms (4) · Ependymoma (3) · Glioblastoma (3) · Medulloblastoma (3) · Oligodendroglioma (3) · Familial ependymoma (2) · Glioma (2) · Gliosarcoma (2) · Blast Crisis (1) · Burkitt Lymphoma (1) · Cachexia (1) · Choroid Plexus Neoplasms (1)
Central Nervous System Diseases (10) · Neoplasms by Site (10) · Nervous System Diseases (10) · Nervous System Neoplasms (10) · Spinal Cord Diseases (10) · Neoplasms (9) · Neoplasms by Histologic Type (9) · Neoplasms, Glandular and Epithelial (9) · Neoplasms, Nerve Tissue (9) · Neoplasms, Neuroepithelial (9) · Neuroectodermal Tumors (9) · Neoplasms, Germ Cell and Embryonal (8) · Glioma (7) · Central Nervous System Neoplasms (5) · Brain Diseases (4)
Temozolomide (4) · Bevacizumab (3) · Disulfides (2) · Immunoglobulin G (2) · Radiotherapy (2) · Carboplatin (1) · Chemotherapy, Adjuvant (1) · Cyproheptadine (1) · Erlotinib Hydrochloride (1) · Esketamine (1) · Fluorodeoxyglucose F18 (1) · Irinotecan (1) · Lapatinib (1) · Lomustine (1) · Megestrol Acetate (1)
National Cancer Institute (NCI) (3) · Children's Oncology Group (2) · Beijing Tiantan Hospital (1) · John Yu (1) · National Institutes of Health Clinical Center (CC) (1) · St. Jude Children's Research Hospital (1) · University of South Florida (1)
United States (9) · Canada (3) · Puerto Rico (2) · Australia (1) · China (1) · Netherlands (1) · New Zealand (1) · Switzerland (1)
Alberto Broniscer, MD (1) · Jennifer L. Mayer, MD (1) · John Yu, MD (1) · Kenneth J. Cohen, MD, MBA (1) · Kevin Camphausen, M.D. (1) · Marta Penas-Prado, MD (1) · Maryam Fouladi (1) · Regina I Jakacki (1) · Ruquan Han, M.D., Ph D. (1) · Sridharan Gururangan (1)
PMID 17705175, PMID 18989154, PMID 20725730, PMID 21339192, PMID 21345842, PMID 36841794, PMID 38501980, PMID 42788739
U10CA098543 (2), U01CA081457 (1), U10CA081920 (1), U10CA180886 (1)