4 recruiting, 3 completed, 2 not yet recruiting, 2 unknown. 4 Phase 2, 3 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Recruiting 2, Completed 1, Not yet recruiting 1 |
| Not applicable | 3 | Unknown 2, Completed 1 |
Follow Sinonasal Carcinoma: new trials by email Literature Review of Sinonasal Carcinoma trials Research Report on Sinonasal Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Surgery Plus Postoperative Radiotherapy for T4 Sinonasal Adenoid Cystic Carcinoma: A Prospective Observational Study Surgery - Adenoid Cystic Carcinoma, Sinonasal Carcinoma | Recruiting | Eye & ENT Hospital of Fudan University | 70 | 2026-06-01 | 2026-06-17 | |
| SPARE-1st: Surgery Alone vs Surgery Plus Postoperative Radiotherapy for Sinonasal Adenoid Cystic Carcinoma Postoperative Radiotherapy, Observation - Adenoid Cystic Carcinoma, Sinonasal Carcinoma | Not yet recruiting | Eye & ENT Hospital of Fudan University | 200 | 2026-05-01 | 2026-05-12 | |
| A Study of Becotatug Vedotin (MRG003) Combined With Epirubicin as Neoadjuvant Therapy for EGFR-Positive, Unresectable Recurrent Sinonasal Adenoid Cystic Carcinoma Becotatug Vedotin - Adenoid Cystic Carcinoma, Sinonasal Carcinoma | Phase 2 | Recruiting | Eye & ENT Hospital of Fudan University | 40 | 2026-04-28 | 2026-07-28 |
| Epirubicin Interventional Chemotherapy for Sinonasal Adenoid Cystic Carcinoma (SNACC): A Prospective Study Epirubicin (E) - Adenoid Cystic Carcinoma, Sinonasal Carcinoma | Phase 2 | Recruiting | Eye & ENT Hospital of Fudan University | 100 | 2026-01-20 | 2026-05-12 |
| Induction Chemotherapy and Tazemetostat for Locally Advanced SMARCB1-deficient Sinonasal Carcinoma Docetaxel, Cis Platinum, 5-FU - Sinonasal Carcinoma | Phase 2 | Not yet recruiting | Dr. Victor H.F. Lee | 30 | 2023-09-01 | 2023-02-28 |
| HPV in Sinonasal Ca: Retrospective Analysis Association of Human Papilloma Virus (HPV) Serology and Behavioral Risk Factors Sinonasal Carcinoma, HPV-Related Squamous Cell Carcinoma | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 49 | 2021-08-03 | 2025-09-22 | |
| Exercise Training and Behavioral Modification for the Improvement of Physical Activity in Head and Neck Cancer Patients Undergoing Cancer Treatment Medical Device Usage and Evaluation, Consultation, Exercise Intervention - Head and Neck Carcinoma, Hypopharyngeal Carcinoma | Not applicable | Completed | Thomas Jefferson University | 12 | 2021-03-28 | 2025-05-22 |
| Prospective Sinonasal Cancer Multi-institution Study Sinonasal Carcinoma | Recruiting | Mayo Clinic | 200 | 2021-01-01 | 2026-04-03 | |
| Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma Pembrolizumab, Cetuximab - HNSCC, Lip SCC | Phase 2 | Completed | University of California, San Diego | 78 | 2017-03-28 | 2026-10-01 |
| Cell-free Tumor DNA in Head and Neck Cancer Patients Liquid biopsy - Head and Neck Cancer, Head and Neck Neoplasms | Not applicable | Unknown | Christian von Buchwald | 500 | 2017-02-01 | 2021-09-21 |
| Intensity-Modulated or Proton Radiation Therapy for Sinonasal Malignancy Proton radiation therapy, Intensity-modulated radiotherapy - Adenoid Cystic Carcinoma, Squamous Cell Carcinoma | Not applicable | Unknown | Massachusetts General Hospital | 45 | 2011-07-12 | 2023-09-21 |
| Tazemetostat Expanded Access Program for Adults With Solid Tumors Tazemetostat - Epithelioid Sarcoma (Ex-US Only), Spindle Cell Sarcoma | No longer available | Epizyme, Inc. | 2026-07-02 |
Carcinoma, Adenoid Cystic (5) · Hypopharyngeal Neoplasms (3) · Laryngeal Neoplasms (3) · Mouth Neoplasms (3) · Oropharyngeal Neoplasms (3) · Head and Neck Neoplasms (2) · Nasopharyngeal Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (2) · Carcinoma (1) · Carcinoma, Mucoepidermoid (1) · Carcinoma, Renal Cell (1) · Carcinoma, Squamous Cell (1) · Chondrosarcoma (1) · Desmoplastic Small Round Cell Tumor (1) · Esthesioneuroblastoma, Olfactory (1)
Neoplasms (9) · Neoplasms by Histologic Type (8) · Neoplasms, Glandular and Epithelial (8) · Carcinoma (7) · Adenocarcinoma (6) · Neoplasms by Site (5) · Respiratory Tract Diseases (4) · Respiratory Tract Neoplasms (4) · Laryngeal Diseases (3) · Mouth Diseases (3) · Otorhinolaryngologic Diseases (3) · Otorhinolaryngologic Neoplasms (3) · Pharyngeal Diseases (3) · Pharyngeal Neoplasms (3) · Stomatognathic Diseases (3)
Surgical Procedures, Operative (2) · tazemetostat (2) · Behavior Therapy (1) · Cetuximab (1) · Chemoradiotherapy (1) · Cisplatin (1) · Docetaxel (1) · Epirubicin (1) · Fluorouracil (1) · Liquid Biopsy (1) · Observation (1) · Protons (1) · Radiotherapy, Intensity-Modulated (1) · Referral and Consultation (1) · pembrolizumab (1)
Eye & ENT Hospital of Fudan University (4) · Christian von Buchwald (1) · Dr. Victor H.F. Lee (1) · Epizyme, Inc. (1) · Massachusetts General Hospital (1) · Mayo Clinic (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · Thomas Jefferson University (1) · University of California, San Diego (1)
United States (5) · China (4) · Denmark (1)
Annie W Chan, MD (1) · Assuntina Sacco, M.D. (1) · Christian Von Buchwald, MD, DMSc (1) · Jake Eide, MD (1) · Nyall London, M.D. (1) · Quan Liu, M.D. (1) · Victor Ho Fun Lee, MD (1)
PMID 16757203, PMID 37097003, PMID 17960615, PMID 21612974, PMID 12112535, PMID 17761983, PMID 24033920, PMID 25456010, PMID 28551643, PMID 30447126, PMID 31463986, PMID 32629365, PMID 33989559, PMID 38539566, PMID 39097677, PMID 40979299, PMID 41089828, PMID 8280659
P01CA021239 (1)