8 completed, 1 enrolling by invitation, 1 recruiting, 1 unknown. 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1 | Completed 1 |
Follow Sex Chromosome Aberrations: new trials by email Literature Review of Sex Chromosome Aberrations trials Research Report on Sex Chromosome Aberrations
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk Assessment Pregnant Individuals, Aneuploidy | Recruiting | BillionToOne Inc. | 1000 | 2026-01-10 | 2026-10-15 | |
| Clinical and Genetic Aspects in Fetuses and Children With Sex Chromosome Disorders Sex Chromosome Disorders | Enrolling by invitation | University of Aarhus | 300 | 2024-09-01 | 2026-01-14 | |
| Endocrine, Metabolic, Cardiovascular and Immunological Aspects of Sex Chromosome Abnormalities in Relation to Genotype No intervention other than obtaining biopsies - Sex Chromosome Abnormality, Klinefelter Syndrome | Unknown | University of Aarhus | 320 | 2022-06-13 | 2023-11-29 | |
| SNP-based Microdeletion and Aneuploidy RegisTry (SMART) 22q11 Deletion Syndrome, DiGeorge Syndrome | Completed | Natera, Inc. | 20960 | 2015-04-01 | 2021-01-29 | |
| High Risk Multiple Gestation Study Trisomy 13, Trisomy 18 | Completed | Natera, Inc. | 99 | 2014-08-01 | 2019-06-13 | |
| Multiple Gestation Study Trisomy 13, Trisomy 18 | Completed | Natera, Inc. | 354 | 2013-03-01 | 2019-08-26 | |
| Development of Non-invasive Prenatal Screening Test for Microdeletions Based on Fetal DNA Isolated From Maternal Blood Trisomy 21, Trisomy 18 | Completed | Natera, Inc. | 1059 | 2012-11-01 | 2020-12-30 | |
| Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA Microdeletion Syndromes, Trisomy 21 | Completed | Natera, Inc. | 216 | 2012-10-01 | 2019-08-26 | |
| Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome Testosterone gel 1%, Placebo gel - Klinefelter Syndrome, XXY Syndrome | Not applicable | Completed | University of Colorado, Denver | 48 | 2012-03-01 | 2021-08-10 |
| Non-invasive Prenatal Diagnostic Validation Study Blood draw, Cheek swab/Saliva Sampling - Chromosome 13 Aneuploidy, Chromosome 18 Aneuploidy | Completed | Natera, Inc. | 1781 | 2011-09-01 | 2013-07-02 | |
| Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure Turner Syndrome, Ovarian Failure, Premature | Completed | National Eye Institute (NEI) | 72 | 2007-05-07 | 2018-02-14 |
Turner Syndrome (8) · Down Syndrome (7) · Trisomy 13 Syndrome (7) · Trisomy 18 Syndrome (7) · Klinefelter Syndrome (4) · Aneuploidy (2) · DiGeorge Syndrome (2) · 22q11 Deletion Syndrome (1) · Angelman Syndrome (1) · Cardiovascular Diseases (1) · Chromosome 1p36 Deletion Syndrome (1) · Cri-du-Chat Syndrome (1) · Disease (1) · Eye Abnormalities (1)
Chromosome Aberrations (11) · Chromosome Disorders (11) · Congenital Abnormalities (11) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (11) · Genetic Diseases, Inborn (11) · Pathologic Processes (11) · Pathological Conditions, Signs and Symptoms (11) · Cardiovascular Abnormalities (10) · Endocrine System Diseases (10) · Heart Defects, Congenital (10) · Heart Diseases (10) · Cardiovascular Diseases (9) · Disorders of Sex Development (9) · Female Urogenital Diseases (9) · Female Urogenital Diseases and Pregnancy Complications (9)
Natera, Inc. (6) · University of Aarhus (2) · BillionToOne Inc. (1) · National Eye Institute (NEI) (1) · University of Colorado, Denver (1)
United States (9) · Denmark (2) · Spain (2) · Australia (1) · India (1) · Ireland (1) · Malaysia (1) · Sweden (1) · Taiwan (1) · United Kingdom (1)
Peer Dar, MD (2) · Brian Kirshon, MD (1) · Claus Gravholt, Prof (1) · Errol Norwitz, MD, PhD (1) · Janine A Clayton, M.D. (1) · Joanne Stone, MD (1) · Julia Wynn, MS, MS, CGC (1) · Kim Martin, MD (1) · Mary Norton, MD (1) · Matthew Rabinowitz, PhD (1) · Nicole Tartaglia, MD (1) · Rajeevi Madankumar, MD (1) · Robert Carpenter, MD (1) · Robert Lamar Parker, MD (1)
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K23NS070337 (1)