32 completed, 28 unknown, 24 recruiting, 6 not yet recruiting. 53 Not applicable, 7 Phase 3, 5 Phase 2, 3 Phase 1, 2 Phase 4.
Follow this condition Literature Review of Sentinel Lymph Node trials Research Report on Sentinel Lymph Node
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Non-inferiority Study of Indocyanine Green-guided Sentinel Lymph Node Mapping Versus Conventional Lymph Node Dissection in Esophageal Cancer ICG-guided sentinel lymph node dissection, ICG-guided systematic lymph node dissection - Esophageal Cancer, Sentinel Lymph Node | Phase 3 | Not yet recruiting | Fujian Medical University Union Hospital | 200 | 2026-10-01 | 2026-08-26 |
| Augmented-Reality ICG Fluorescence Second-Look for Residual Nodal Disease After Axillary Dissection in Breast Cancer Augmented-reality ICG fluorescence second-look imaging - Breast Cancer, Breast Neoplasms | Not applicable | Not yet recruiting | Ss. Cyril and Methodius University of Skopje | 30 | 2026-07-10 | 2026-07-10 |
| Device Validation of Augmented-Reality ICG Fluorescence Imaging for Sentinel Lymph Node Detection in Breast Cancer AR-ICG near-infrared fluorescence imaging - Breast Cancer, Breast Neoplasms | Not yet recruiting | Ss. Cyril and Methodius University of Skopje | 200 | 2026-07-01 | 2026-07-06 | |
| The Value of Indocyanine Green-guided Near-infrared Fluorescence Technology in Tracing Sentinel Lymph Nodes During Esophagectomy Minimally invasive surgery for esophageal cancer using near-infrared indocyanine green fluorescence to visualize the sentinel lymph node - Esophageal Cancer, Sentinel Lymph Node | Phase 3 | Not yet recruiting | Fujian Medical University Union Hospital | 144 | 2026-01-01 | 2025-12-24 |
| EpCAM-Targeted Surface-Enhanced Raman Spectroscopy Nanotags for Rapid Evaluation of Surgical Margins and Sentinel Lymph Node Metastasis Status in Breast Cancers SERS detection - Sentinel Lymph Node, Breast Cancers | Not yet recruiting | Yunnan Cancer Hospital | 40 | 2025-06-15 | 2025-06-12 | |
| Comparison of Two-Position and Four-Position Cervical Injection Techniques for Sentinel Lymph Node Mapping in Endometrial Cancer Using Methylene Blue Sentinel Lymph Node Detection/Cervical Methylene Blue Injection - Endometrial Neoplasms, Endometrial Cancer Stage I | Not applicable | Recruiting | Dokuz Eylul University | 100 | 2025-05-01 | 2025-06-27 |
| Implementation of Indocyanine Green to Identify Sentinel Lymph Nodes During Surgery for Breast Cancer Technetium (99mTc), Indocyanine Green, Sentinel lymph node biopsy - Breast Cancer, Sentinel Lymph Node Biopsy (SLNB) | Not applicable | Recruiting | Isabelle Henskens | 1760 | 2025-04-18 | 2026-06-25 |
| Sentinel Node Biopsy Versus Limited Elective Neck Dissection in Early Cancers of Oral Cavity NoDe Negative Sentinel Node Biopsy, Limited Elective Neck Dissection - Mouth Neoplasms, Oral Cancers | Not applicable | Recruiting | Tata Memorial Hospital | 508 | 2025-04-16 | 2025-07-17 |
| Rapid Assessment of Sentinel Lymph Node Metastasis Status Using a Pan-CK-targeting NIR-II Fluorescent Probe in Breast Cancer NIR-II probe (i.e ICG-CK) incubation solution - Breast Cancer Metastatic, Sentinel Lymph Node | Recruiting | Yunnan Cancer Hospital | 60 | 2025-02-01 | 2025-09-04 | |
| Correlation of Pelvic Sentinel Lymph Node With Superficial Vein Retroperitoneal pelvic lymphatic and uterine vessel dissection - Sentinel Lymph Node, Superficial Uterine Vein | Not applicable | Unknown | Istanbul University | 100 | 2024-12-22 | 2024-12-18 |
| Sentinel Node and Organ-sparing Surgery in Stage I Colon Carcinoma Organ-sparing surgery, Standard of care segmental resection - Colon Cancer, Colon Adenocarcinoma | Not applicable | Recruiting | Meander Medical Center | 341 | 2024-12-12 | 2025-11-20 |
| Tumor-Targeted-NIR-II Fluorescent Molecular Probes for the Identification of Breast Cancer Tissue and SLN Metastatic Status NIR-II Probe(i.e ICG-POL6326) incubation solution - Breast Cancer, Sentinel Lymph Node | Recruiting | Yunnan Cancer Hospital | 40 | 2024-09-01 | 2024-12-03 | |
| Trop2-targeting NIR-II Molecular Probe for Breast Cancer Precise Surgery TTP-ICG incubation solution - Breast Cancer, Sentinel Lymph Node | Completed | Yunnan Cancer Hospital | 59 | 2024-05-13 | 2026-04-03 | |
| Omission of Axillary Surgery in Breast Cancer Patients omission of SLNB in SentiOMIT or omission of ALND in SentiMACRO - Breast Cancer, Sentinel Lymph Node | Not applicable | Recruiting | KK Women's and Children's Hospital | 350 | 2024-02-06 | 2024-02-14 |
| Application of EndoScell Intraoperative Cellular Probing Technology for Early-Stage Breast Cancer EndoScell Scaner (ES) novel intraoperative cellular probing technology - Breast Cancer, Sentinel Lymph Node | Not applicable | Recruiting | Fudan University | 709 | 2024-01-30 | 2025-04-04 |
| Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Initially Node Positive Breast Cancer Patients, Could it Omit Axillary Dissection ? sentinle lymphnode biopsy - Sentinel Lymph Node | Not applicable | Unknown | Assiut University | 30 | 2023-11-30 | 2023-11-14 |
| Sentinel Lymph Nodes Biopsy in Cervical Cancer sentinel lymph node biopsy, comprehensive pelvic lymphadenectomy - Sentinel Lymph Node | Unknown | Far Eastern Memorial Hospital | 70 | 2023-10-14 | 2024-06-17 | |
| Sentinel Lymph Node in Early-Stage Endometrium Cancer Sentinel Lymph Node Mapping With Double Tracer and Double Injection Sites in Early-Stage Endometrium Cancer, charcoal injection to uterus to map sentinel lymph nodes - Sentinel Lymph Node, Endometrial Cancer | Not applicable | Unknown | Istanbul University | 100 | 2023-07-01 | 2024-11-25 |
| Omission of SLNB in CN0 Early Breast Cancer Omit SLNB - Breast Cancer, Clinically Assessed Negative Axillary Lymph Nodes | Not applicable | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 311 | 2023-06-21 | 2024-10-15 |
| Optical Guided Sentinel Node Biopsy for Staging of Vulvar Cancer Vulva Cancer, Sentinel Lymph Node | Recruiting | Copenhagen University Hospital, Rigshospitalet | 100 | 2023-05-01 | 2023-12-13 |
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Breast Neoplasms (43) · Endometrial Neoplasms (13) · Lymphatic Metastasis (10) · Colonic Neoplasms (5) · Neoplasm Metastasis (5) · Ovarian Neoplasms (4) · Vulvar Neoplasms (4) · Colorectal Neoplasms (3) · Melanoma (3) · Stomach Neoplasms (3) · Uterine Cervical Neoplasms (3) · Esophageal Neoplasms (2) · Margins of Excision (2) · Squamous Cell Carcinoma of Head and Neck (2) · Carcinoma, Intraductal, Noninfiltrating (1)
Neoplasms (84) · Neoplasms by Site (83) · Skin Diseases (45) · Skin and Connective Tissue Diseases (45) · Breast Diseases (43) · Genital Diseases (24) · Urogenital Diseases (24) · Urogenital Neoplasms (24) · Female Urogenital Diseases (23) · Female Urogenital Diseases and Pregnancy Complications (23) · Genital Diseases, Female (23) · Genital Neoplasms, Female (23) · Pathological Conditions, Signs and Symptoms (18) · Pathologic Processes (17) · Neoplastic Processes (15)
Sentinel Lymph Node Biopsy (9) · Indocyanine Green (8) · Methylene Blue (3) · ferumoxides (2) · Biopsy, Large-Core Needle (1) · Cisplatin (1) · Drug Therapy (1) · Ice (1) · Lymph Node Excision (1) · Minimally Invasive Surgical Procedures (1) · Neoadjuvant Therapy (1) · Optical Imaging (1) · Radioactive Tracers (1) · Technetium (1) · Technetium-99 (1)
Yunnan Cancer Hospital (4) · Fujian Medical University Union Hospital (3) · Istanbul University (3) · Meander Medical Center (3) · Chinese Academy of Sciences (2) · Copenhagen University Hospital, Rigshospitalet (2) · Hospital Universitari de Bellvitge (2) · IRCCS San Raffaele (2) · Isabelle Henskens (2) · Jewish General Hospital (2) · National Taiwan University Hospital Hsin-Chu Branch (2) · Ss. Cyril and Methodius University of Skopje (2) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (2) · University Hospital, Ghent (2) · University Hospitals of Derby and Burton NHS Foundation Trust (2)
China (18) · Turkey (Türkiye) (10) · Italy (8) · Netherlands (8) · United States (8) · Sweden (7) · Spain (6) · Canada (4) · Denmark (3) · South Korea (3) · Taiwan (3) · Australia (2) · Belgium (2) · Hong Kong (2) · North Macedonia (2)
Amit Goyal, MS, MD, FRCS (2) · Esther Consten, prof. dr. (2) · Yung-Chun Hsieh, MD (2) · Alex Mlynarek, MD (1) · Amparo Garcia-Tejedor, MDPhD (1) · Andreas Karakatsanis, PhD (1) · Andreas Obermair, Prof (1) · Andreas U Karakatsanis, MD, PhD (1) · Annemiek Doeksen, MD, PhD (1) · Ava Kwong, Professor (1) · Bang Wool Eom, MD, PhD (1) · Bin Zheng (1) · China Fujian (1)
PMID 24358319, PMID 25439688, PMID 27497181, PMID 28898379, PMID 38598571, PMID 39966355, PMID 11192930, PMID 14965682, PMID 15614159, PMID 22120175, PMID 24322530, PMID 24484967, PMID 25466980, PMID 25997792, PMID 26365441, PMID 26754343, PMID 27117158, PMID 28375928, PMID 28577885, PMID 28726040, PMID 29194194, PMID 29224846, PMID 29290809, PMID 29787938, PMID 30286945, PMID 30318103, PMID 30353577, PMID 30833435, PMID 30859424, PMID 31245160, PMID 31345606, PMID 31450214, PMID 31490376, PMID 31601646, PMID 31796533, PMID 31818860, PMID 31833973, PMID 31863354, PMID 31871114, PMID 31882459, PMID 32693797, PMID 33025481, PMID 33879180, PMID 34728527, PMID 34877830, PMID 35184724, PMID 36653060, PMID 37075495, PMID 37621686, PMID 37918956
2016 (1), 2019 (1), T32CA090217 (1)