1 active not recruiting, 1 completed, 1 recruiting, 1 unknown. 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Active not recruiting 1, Completed 1, Recruiting 1, Unknown 1 |
Follow Sclerosis: new trials by email Literature Review of Sclerosis trials Research Report on Sclerosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases BMS-986515, Fludarabine, Cyclophosphamide - Refractory Autoimmune Diseases | Phase 1 | Recruiting | Juno Therapeutics, Inc., a Bristol-Myers Squibb Company | 125 | 2025-09-04 | 2026-07-14 |
| A Study of CNTY-101 in Participants With Refractory B Cell-mediated Autoimmune Diseases CNTY-101, IL-2, Lymphodepleting Chemotherapy - Systemic Lupus Erythematosus, Lupus Nephritis | Phase 1 | Active not recruiting | Century Therapeutics, Inc. | 6 | 2025-02-06 | 2026-01-08 |
| PET Study of PIPE-791 in Healthy Volunteers and Volunteers With PrMS and IPF PIPE-791 - Idiopathic Pulmonary Fibrosis (IPF), Idiopathic Pulmonary Fibrosis | Phase 1 | Completed | Contineum Therapeutics | 16 | 2024-12-09 | 2025-08-06 |
| Molecular Imaging Modality by Positron Emission Tomography Using 18F-X : Study of Microglial Activation in Amyotrophic Lateral Sclerosis 18F-X PET SCAN - Amyotrophic Lateral Sclerosis, Bulbar Disease | Phase 1 | Unknown | University Hospital, Tours | 30 | 2007-01-01 | 2010-03-19 |
Autoimmune Diseases (3) · Dermatomyositis (2) · Lupus Erythematosus, Systemic (2) · Lupus Nephritis (2) · Myositis (2) · Polymyositis (2) · Scleroderma, Diffuse (2) · Scleroderma, Systemic (2) · Amyotrophic Lateral Sclerosis (1) · Arthritis, Rheumatoid (1) · Autoimmune Diseases of the Nervous System (1) · Connective Tissue Diseases (1) · Demyelinating Autoimmune Diseases, CNS (1) · Demyelinating Diseases (1)
Pathological Conditions, Signs and Symptoms (4) · Nervous System Diseases (3) · Neuromuscular Diseases (3) · Pathologic Processes (3) · Central Nervous System Diseases (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Glomerulonephritis (2) · Immune System Diseases (2) · Kidney Diseases (2) · Male Urogenital Diseases (2) · Muscular Diseases (2) · Musculoskeletal Diseases (2) · Nephritis (2) · Skin and Connective Tissue Diseases (2)
Cyclophosphamide (1) · Interleukin-2 (1) · fludarabine (1) · tocilizumab (1)
Century Therapeutics, Inc. (1) · Contineum Therapeutics (1) · Juno Therapeutics, Inc., a Bristol-Myers Squibb Company (1) · University Hospital, Tours (1)
France (2) · United States (2) · Australia (1) · Brazil (1) · Czechia (1) · Germany (1) · Israel (1) · Poland (1) · Romania (1) · Spain (1) · United Kingdom (1)
Stephen Huhn, MD (1)