2 completed, 1 not yet recruiting, 1 unknown. 4 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Not yet recruiting 1, Unknown 1 |
| Phase 3 | 2 | Completed 1, Not yet recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow Schistosoma Mansoni: new trials by email Literature Review of Schistosoma Mansoni trials Research Report on Schistosoma Mansoni
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Different Treatment Frequencies for Hepatic Fibrosis Due to Schistosomiasis Praziquantel 40 mg/kg per dose given once annually, Praziquantel 40 mg/kg given three times per year - Schistosomiasis, Schistosoma Mansoni | Phase 2 / Phase 3 | Not yet recruiting | Rhode Island Hospital | 600 | 2026-11-01 | 2026-08-12 |
| Sm-p80 Schistosomiasis Challenge Study Sm-p80 + GLA-SE Vaccine, Placebo, Schistosoma mansoni infection - Schistosoma Mansoni, Schistosomiasis | Phase 2 | Unknown | Leiden University Medical Center | 48 | 2024-09-01 | 2023-10-17 |
| Clinical Evaluation of Ujiplus® Against Schistosoma Mansoni Ujiplus®, Praziquantel 400mg - Schistosoma Mansoni | Phase 2 / Phase 3 | Completed | Kenya Medical Research Institute | 400 | 2021-05-06 | 2022-07-12 |
| Sm-TSP-2 Schistosomiasis Vaccine in Healthy Ugandan Adults Sm-TSP-2/Alhydrogel® vaccine, Sm-TSP-2/Alhydrogel® vaccine plus AP 10-701, ENGERIX-B Hepatitis B Vaccine - Schistosomiasis, Schistosoma Mansoni | Phase 1 / Phase 2 | Completed | Baylor College of Medicine | 290 | 2019-10-07 | 2025-11-04 |
Schistosomiasis (4) · Hypertension, Portal (1) · Liver Cirrhosis (1)
Helminthiasis (4) · Infections (4) · Parasitic Diseases (4) · Trematode Infections (4) · Vector Borne Diseases (4) · Digestive System Diseases (1) · Fibrosis (1) · Liver Diseases (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
Praziquantel (2)
Baylor College of Medicine (1) · Kenya Medical Research Institute (1) · Leiden University Medical Center (1) · Rhode Island Hospital (1)
Uganda (2) · Kenya (1)
Elijah M Songok, PhD (1) · Hannah Kibuuka, MD (1) · Meta Roestenberg, Prof (1)
R01AI184979 (1)