7 completed, 1 active not recruiting, 1 terminated, 1 withdrawn. 10 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 7, Active not recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow Retinitis: new trials by email Literature Review of Retinitis trials Research Report on Retinitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa Due to the P23H Mutation in the RHO Gene QR-1123, Sham procedure - Autosomal Dominant Retinitis Pigmentosa, Eye Diseases | Phase 1 / Phase 2 | Active not recruiting | ProQR Therapeutics | 11 | 2019-10-07 | 2022-05-06 |
| Stem Cell Transplantation in Ocular Lesions of Behcet's Disease Autologous Stem Cell Transplantation - Retinitis, Behcet's Syndrome | Phase 1 | Terminated | Tehran University of Medical Sciences | 5 | 2007-12-01 | 2015-11-10 |
| A Study of Ganciclovir in the Treatment of Cytomegalovirus of the Eyes Ganciclovir - Cytomegalovirus Retinitis, HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 25 | 2021-11-04 | |
| Foscarnet Treatment of Serious CMV Retinitis Infection in Patients With Acquired Immunodeficiency Syndrome Foscarnet sodium - Cytomegalovirus Retinitis, HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 53 | 2021-11-03 | |
| A Phase I/II Open-Labelled Trial of Intravitreal Ganciclovir Salvage Therapy for AIDS Patients With Active CMV Retinitis Who Are Intolerant of Systemic Therapy Ganciclovir - Cytomegalovirus Retinitis, HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 38 | 2021-10-27 | |
| A Phase I Pharmacokinetic and Tolerance Study of 28-Day Regimens of Oral Ganciclovir Ganciclovir - Cytomegalovirus Retinitis, HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 48 | 2021-11-03 | |
| A Study of Foscarnet Plus Ganciclovir in the Treatment of Cytomegalovirus of the Eye in Patients With AIDS Who Have Already Been Treated With Ganciclovir Foscarnet sodium, Ganciclovir - Cytomegalovirus Retinitis, HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 30 | 2021-11-04 | |
| A Phase I Study of the Safety of Proleukin (Aldesleukin) in Combination With Ganciclovir and Antiretroviral Therapy in HIV Seropositive Patients With Cytomegalovirus (CMV) Retinitis Aldesleukin - Cytomegalovirus Retinitis, HIV Infections | Phase 1 | Completed | Chiron Corporation | 2005-06-24 | ||
| A Study of Cidofovir in HIV-Infected Children With Cytomegalovirus (CMV) Disease Cidofovir, Probenecid - Cytomegalovirus Infections, Cytomegalovirus Retinitis | Phase 1 | Withdrawn | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-10-29 | ||
| A Phase I/II Trial to Assess the Safety and Tolerance of Escalating Doses of a Human Anti-Cytomegalovirus Monoclonal Antibody (SDZ MSL-109) in Patients With the Acquired Immunodeficiency Syndrome and CMV Retinitis Sevirumab - Cytomegalovirus Retinitis, HIV Infections | Phase 1 | Completed | Sandoz | 2005-06-24 |
Cytomegalovirus Retinitis (8) · HIV Infections (8) · Acquired Immunodeficiency Syndrome (7) · Cytomegalovirus Infections (6) · Multiple Acyl Coenzyme A Dehydrogenase Deficiency (6) · AIDS-Related Opportunistic Infections (5) · Behcet Syndrome (1) · Eye Diseases (1) · Eye Diseases, Hereditary (1) · Multiple Pterygium Syndrome, Autosomal Dominant (1) · Night Blindness, Congenital Stationary, Autosomal Dominant 1 (1) · Papilledema (1) · Retinal Diseases (1) · Retinal Dystrophies (1)
Eye Diseases (9) · Retinal Diseases (9) · Blood-Borne Infections (8) · Communicable Diseases (8) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (8) · DNA Virus Infections (8) · Eye Infections (8) · Eye Infections, Viral (8) · Genetic Diseases, Inborn (8) · Genital Diseases (8) · Herpesviridae Infections (8) · Immune System Diseases (8) · Immunologic Deficiency Syndromes (8) · Infections (8) · Lentivirus Infections (8)
Ganciclovir (4) · Foscarnet (2) · Cidofovir (1) · Probenecid (1) · aldesleukin (1) · sevirumab (1)
National Institute of Allergy and Infectious Diseases (NIAID) (6) · Chiron Corporation (1) · ProQR Therapeutics (1) · Sandoz (1) · Tehran University of Medical Sciences (1)
United States (8) · Iran (1)
Behrouz Nikbin, MD (1) · Dankner W (1) · Fereydoun Davatchi, MD (1) · Hardy WD (1) · Holland GN (1) · Hormoz Shams, MD (1) · Jacobson M (1) · Jacobson MA (1) · Polsky B (1) · Spector S (1)