434 completed. 434 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 434 | Completed 434 |
Follow Respiratory Hypersensitivity: new trials by email Literature Review of Respiratory Hypersensitivity trials Research Report on Respiratory Hypersensitivity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| IV DEXAMETHASONE VS. METHYLPREDNISOLONE IN CHILDREN WITH SEVERE ASTHMA EXACERBATION Intravenous Dexamethasone, Intravenous Methylprednisolone - Status Asthmaticus, Asthma (Diagnosis) | Phase 4 | Completed | Istanbul Medeniyet University | 129 | 2025-09-01 | 2026-07-28 |
| Study to Assess Safety and Efficacy of Fexofenadine Hydrochloride (HCL) + Pseudoephedrine HCL Fixed Dose Combination in Indian Male and Female Participants With Allergic Rhinitis (AR) Who Are 12 Years and Above Fexofenadine HCL and pseudoephedrine HCL - Rhinitis Allergic | Phase 4 | Completed | Sanofi | 203 | 2025-06-15 | 2026-02-17 |
| Evaluation of Treatments for Allergic Rhinitis (Rhinal 2) ALLERSPRAY-G (device A), PCNS (device B) - Allergic Rhinitis | Phase 4 | Completed | University Hospital, Clermont-Ferrand | 35 | 2025-03-03 | 2025-06-13 |
| Oxymetazoline Bridge Therapy With Intranasal Corticosteroids in Pediatric Allergic Rhinitis Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 100 mcg, Oxymetazoline 0.05% nasal solution - Persistent Allergic Rhinitis | Phase 4 | Completed | Dr. Behcet Uz Children's Hospital | 76 | 2025-01-02 | 2026-05-18 |
| Inhaling Penehyclidine to Prevent Perioperative Respiratory Adverse Events in Children at Risk Undergoing Sevoflurane Anesthesia Penehyclidine hydrochloride, Normal Saline - Respiratory Hypersensitivity, Perioperative Respiratory Adverse Events | Phase 4 | Completed | Sun Yat-sen University | 204 | 2024-11-12 | 2026-10-02 |
| Establish FeNO Cut-off Value for Predicting Budesonide-formoterol Response in Chronic Cough Suggestive of CVA Patients. Budesonide-Formoterol treatment - Cough-Variant Asthma | Phase 4 | Completed | AstraZeneca | 1000 | 2024-10-18 | 2025-09-18 |
| Study to Investigate Changes in Airway Inflammation, Symptoms, and Rescue Therapy Utilization With AIRSUPRA Compared to Albuterol as Needed in Adults With Mild Asthma Albuterol/Budesonide, Albuterol - Mild Asthma | Phase 4 | Completed | AstraZeneca | 101 | 2024-09-11 | 2026-02-27 |
| Evaluation of Time-Sensitive Nebulization Mode Converter Cross-over Nebulization Modes Comparison System - Aerosol Therapy, Asthma | Phase 4 | Completed | Beni-Suef University | 36 | 2024-09-01 | 2026-06-08 |
| A Pilot Study of Mirabegron and Montelukast in Cirrhotic Patients Mirabegron 100 mg, Mirabegron 50mg, mirabegron 25 mg - Cirrhosis, Asthma | Phase 4 | Completed | Kafrelsheikh University | 78 | 2024-07-01 | 2026-04-16 |
| BenRalizumab Effect on Airway Remodeling in Severe asTHma Benralizumab 30 mg/ml - Asthma; Eosinophilic, Airway Remodeling | Phase 4 | Completed | Aristotle University Of Thessaloniki | 36 | 2024-03-01 | 2026-10-28 |
| Bioequivalence Study of Methacholine for Inhalation (pharmacodynamics) Test preparation：Methylcholine chloroacetate for inhalation, Reference preparation：Methylcholine chloroacetate for inhalation（Provocholine） - Asthma | Phase 4 | Completed | China-Japan Friendship Hospital | 40 | 2024-02-24 | 2024-12-10 |
| Individualizing Treatment for Asthma in Primary Care Asthma Symptom Monitoring online tools, Inhaled Steroids, Azithromycin Pill - Asthma, Bronchial Diseases | Phase 4 | Completed | DARTNet Institute | 103 | 2024-02-01 | 2025-04-20 |
| Reversibility of Methacholine Induced Bronchoconstriction salbutamol aqueous solution, salbutamol pressurized metered dose inhaler, placebo - Asthma | Phase 4 | Completed | University of Saskatchewan | 16 | 2024-01-12 | 2026-05-04 |
| A Comparative Study of Adding Ipratropium to Salbutamol for the Treatment of Asthma Attack in Children Salbutamol (Ventolin®), salbutamol + ipratropium bromide nebules - Asthma Exacerbation, Children | Phase 4 | Completed | Children's Hospital and Institute of Child Health, Multan | 60 | 2024-01-01 | 2025-04-09 |
| Budesonide Nasal Irrigation Versus Fluticasone Propionate Nasal Spray in Treating Allergic Rhinitis Patients Budesonide buffered with 0.9% isotonic saline., Fluticasone propionate nasal spray., 0.9% saline for nasal irrigation. - Nasal Allergy | Phase 4 | Completed | Benha University | 360 | 2023-08-15 | 2025-03-05 |
| ICS+LABA Vs. ICS+LABA+Omalizumab: Impact on Asthma Control and Gene Expression Foster BDP/Formoterol, Omalizimab - Asthma Patients | Phase 4 | Completed | Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation | 26 | 2023-01-01 | 2025-03-11 |
| Diphenhydramine and Sweating Placebo, Diphenhydramine - Diphenhydramine Causing Adverse Effects in Therapeutic Use, Hyperthermia | Phase 4 | Completed | Lakehead University | 20 | 2022-11-21 | 2023-09-13 |
| BURAN: Benralizumab on Airway Dynamics in Severe Eosinophilic Asthma Using Functional Respiratory Imaging Benralizumab - Asthma | Phase 4 | Completed | AstraZeneca | 45 | 2022-10-11 | 2025-03-25 |
| CARE FOR ALL：an Evaluation of an Asthma QIP QIP intervention - Asthma | Phase 4 | Completed | AstraZeneca | 1500 | 2022-07-29 | 2026-01-02 |
| Periostin-guided Withdrawal of Inhaled Corticosteroids in Patients With Non-eosinophilic Asthma Tapering of inhaled corticosteroid (ICS) treatment - Asthma | Phase 4 | Completed | Hvidovre University Hospital | 20 | 2022-06-01 | 2025-03-17 |
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Asthma (308) · Rhinitis, Allergic (74) · Rhinitis, Allergic, Seasonal (48) · Rhinitis, Allergic, Perennial (30) · Pulmonary Disease, Chronic Obstructive (18) · Rhinitis (12) · Hypersensitivity (11) · Pulmonary Eosinophilia (8) · Emergencies (7) · Asthma, Exercise-Induced (5) · Respiratory Sounds (5) · Lymphoma, Follicular (4) · Motor Activity (4) · Nasal Obstruction (4)
Hypersensitivity, Immediate (434) · Immune System Diseases (432) · Respiratory Tract Diseases (432) · Hypersensitivity (423) · Bronchial Diseases (311) · Lung Diseases, Obstructive (308) · Lung Diseases (307) · Otorhinolaryngologic Diseases (140) · Nose Diseases (139) · Rhinitis (125) · Rhinitis, Allergic (62) · Pathological Conditions, Signs and Symptoms (51) · Pathologic Processes (32) · Infections (27)
Fluticasone (52) · montelukast (47) · Albuterol (36) · Budesonide (30) · Fluticasone-Salmeterol Drug Combination (27) · Omalizumab (20) · fexofenadine (17) · Mometasone Furoate (16) · Salmeterol Xinafoate (16) · levocetirizine (16) · desloratadine (12) · fluticasone furoate (12) · Beclomethasone (11) · Cetirizine (11) · ciclesonide (10)
GlaxoSmithKline (59) · Organon and Co (34) · AstraZeneca (23) · Sanofi (12) · University of Dundee (12) · University of Saskatchewan (11) · Centre of Chinese Medicine, Georgia (8) · University of Chicago (8) · Medical University of Lodz (7) · Imperial College London (6) · Novartis (6) · Boehringer Ingelheim (5) · UCB Pharma (5) · Alcon Research (4) · Kecioren Education and Training Hospital (4)
United States (144) · Canada (50) · United Kingdom (44) · Germany (32) · Italy (28) · Spain (20) · Netherlands (19) · Poland (19) · France (17) · Belgium (16) · Denmark (15) · Sweden (14) · China (13) · Argentina (10) · Russia (10)
Don Cockcroft, MD (6) · Manana Tchaia, MD (6) · Merab Lomia, MD, PhD (6) · Phyllis Diener (5) · Brian Lipworth, MD (4) · Leslie Hendeles, PharmD (4) · Robert M Naclerio, MD (4) · Tamara Tchelidze, MD (4) · Brian J Lipworth, MD (3)
PMID 20167147, PMID 20642206, PMID 32298853, PMID 33369570, PMID 36472162, PMID 37347518, PMID 37536444, PMID 37952772, PMID 11558866, PMID 12045120, PMID 12612294, PMID 15922813, PMID 16140398, PMID 16278257, PMID 16597501, PMID 16687712, PMID 16846553, PMID 16913264, PMID 17046300, PMID 17075269, PMID 17507702, PMID 17610727, PMID 17629923, PMID 17766511, PMID 18331513, PMID 18399898, PMID 18430310, PMID 18583517, PMID 18990678, PMID 19127072, PMID 19134016, PMID 19164187, PMID 19187327, PMID 19291931, PMID 19428097, PMID 19467341, PMID 19496252, PMID 19504468, PMID 19557208, PMID 19632710, PMID 19663124, PMID 19696440, PMID 19788025, PMID 19804441, PMID 19910613, PMID 20110036, PMID 20203244, PMID 20298399, PMID 20350147, PMID 20377116
2015 (4), 2019 (4), 2004 (2), 2014 (2), 2016 (2), 2017 (2), 2005 (1), 2018 (1), P50HL056385 (1), R01HL114899 (1), R18HL092862 (1), U01HL080450 (1)