2 recruiting, 1 completed, 1 unknown, 1 withdrawn. 3 Phase 1, 1 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Recruiting 2, Withdrawn 1 |
| Not applicable | 1 | Completed 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Recurrent Malignant Brain Neoplasm: new trials by email Literature Review of Recurrent Malignant Brain Neoplasm trials Research Report on Recurrent Malignant Brain Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and Young Adult Patients With Resectable, Recurrent Primary Malignant Brain Tumors Ad-hCMV-Flt3L, Ad-hCMV-TK, Biospecimen Collection - Recurrent Diffuse Hemispheric Glioma, H3 G34-Mutant, Recurrent Malignant Brain Neoplasm | Phase 1 | Recruiting | University of Michigan Rogel Cancer Center | 11 | 2026-05-22 | 2026-06-15 |
| Low Dose Versus Standard Dose Dexamethasone for Reduction of Swelling in Patients with Primary or Metastatic Brain Tumors Dexamethasone - Malignant Brain Neoplasm, Metastatic Malignant Neoplasm in the Brain | Phase 2 | Unknown | City of Hope Medical Center | 26 | 2022-04-09 | 2024-09-19 |
| Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer Etoposide, Fludarabine Phosphate, Hematopoietic Cell Transplantation - Anaplastic Ependymoma, Atypical Teratoid/Rhabdoid Tumor | Phase 1 | Withdrawn | M.D. Anderson Cancer Center | 2021-01-14 | 2024-10-26 | |
| CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children Cyclophosphamide, Fludarabine, IL13Ralpha2-specific Hinge-optimized 41BB-co-stimulatory CAR Truncated CD19-expressing Autologous T-Lymphocytes - Malignant Brain Neoplasm, Recurrent Malignant Brain Neoplasm | Phase 1 | Recruiting | City of Hope Medical Center | 18 | 2020-12-11 | 2026-10-15 |
| Novel MRI Techniques for the Characterization and Treatment Assessment of High Grade Brain Lesions Gadobenate Dimeglumine, Gadobutrol, Magnetic Resonance Imaging - Brain Neoplasm, Lymphoma | Not applicable | Completed | M.D. Anderson Cancer Center | 6 | 2020-01-10 | 2022-11-21 |
Brain Neoplasms (5) · Choroid Plexus Carcinoma (1) · Ependymoma (1) · Glioma (1) · Lymphoma (1) · Medulloblastoma (1) · Neuroectodermal Tumors, Primitive (1) · Rhabdoid Tumor (1)
Brain Diseases (5) · Central Nervous System Diseases (5) · Central Nervous System Neoplasms (5) · Neoplasms (5) · Neoplasms by Site (5) · Nervous System Diseases (5) · Nervous System Neoplasms (5) · Neoplasms by Histologic Type (2) · Hemic and Lymphatic Diseases (1) · Immune System Diseases (1) · Immunoproliferative Disorders (1) · Lymphatic Diseases (1) · Lymphoproliferative Disorders (1) · Neoplasms, Complex and Mixed (1) · Neoplasms, Germ Cell and Embryonal (1)
Magnetic Resonance Spectroscopy (2) · Antilymphocyte Serum (1) · Calcium Dobesilate (1) · Cyclophosphamide (1) · Dexamethasone (1) · Etoposide (1) · Hematopoietic Stem Cell Transplantation (1) · Melphalan (1) · Mycophenolic Acid (1) · Specimen Handling (1) · Stem Cell Transplantation (1) · Tacrolimus (1) · Thiotepa (1) · Transurethral Resection of Bladder (1) · Valacyclovir (1)
City of Hope Medical Center (2) · M.D. Anderson Cancer Center (2) · University of Michigan Rogel Cancer Center (1)
United States (4)
Andrea T Franson (1) · Jana L Portnow, MD (1) · Ken-Pin Hwang, MD (1) · Kris M Mahadeo, MD (1) · Leo D Wang (1)
P30CA033572 (2)