3 terminated, 2 completed, 1 withdrawn. 3 Phase 1, 2 Not applicable, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Terminated 2, Completed 1 |
| Not applicable | 2 | Terminated 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 2 |
Follow Recurrent Childhood Anaplastic Astrocytoma: new trials by email Literature Review of Recurrent Childhood Anaplastic Astrocytoma trials Research Report on Recurrent Childhood Anaplastic Astrocytoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors palbociclib isethionate, pharmacological study, laboratory biomarker analysis - Childhood Choroid Plexus Tumor, Childhood Ependymoblastoma | Phase 1 | Terminated | Pediatric Brain Tumor Consortium | 35 | 2014-12-08 | 2021-03-02 |
| 18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas 18F-fluoro-dihydroxyphenylalanine, Positron emission tomography (PET), Computed tomography (CT) - Adult Anaplastic Ependymoma, Adult Anaplastic Oligodendroglioma | Not applicable | Terminated | Erik Mittra | 2 | 2014-12-01 | 2017-03-20 |
| Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery oncolytic HSV-1716, dexamethasone, therapeutic conventional surgery - Recurrent Childhood Anaplastic Astrocytoma, Recurrent Childhood Anaplastic Oligoastrocytoma | Phase 1 | Terminated | Pediatric Brain Tumor Consortium | 2 | 2013-12-01 | 2016-05-30 |
| Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors gallium Ga 68-edotreotide, positron emission tomography, computed tomography - Acoustic Schwannoma, Adult Anaplastic Astrocytoma | Not applicable | Withdrawn | Sue O'Dorisio | 2013-09-01 | 2017-04-28 | |
| Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy cilengitide, laboratory biomarker analysis, pharmacological study - Childhood High-grade Cerebellar Astrocytoma, Childhood High-grade Cerebral Astrocytoma | Phase 2 | Completed | National Cancer Institute (NCI) | 30 | 2008-06-01 | 2018-08-01 |
| Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors lapatinib ditosylate, therapeutic conventional surgery, laboratory biomarker analysis - Recurrent Childhood Anaplastic Astrocytoma, Recurrent Childhood Brain Stem Glioma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 52 | 2004-10-01 | 2014-05-23 |
Astrocytoma (6) · Oligodendroglioma (6) · Glioblastoma (5) · Neoplasms, Neuroepithelial (4) · Medulloblastoma (3) · Optic Nerve Glioma (3) · Brain Neoplasms (2) · Choroid Plexus Neoplasms (2) · Ependymoma (2) · Familial ependymoma (2) · Glioma (2) · Gliosarcoma (2) · Craniopharyngioma (1) · Glioma, Subependymal (1) · Meningioma (1)
Neoplasms (6) · Neoplasms by Histologic Type (6) · Neoplasms, Germ Cell and Embryonal (6) · Neoplasms, Glandular and Epithelial (6) · Neoplasms, Nerve Tissue (6) · Neuroectodermal Tumors (6) · Glioma (4) · Neoplasms by Site (4) · Nervous System Diseases (4) · Nervous System Neoplasms (4) · Brain Diseases (3) · Central Nervous System Diseases (3) · Central Nervous System Neoplasms (3) · Cranial Nerve Diseases (3) · Cranial Nerve Neoplasms (3)
2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole (3) · Magnetic Resonance Spectroscopy (3) · Calcium Dobesilate (1) · Cilengitide (1) · Dexamethasone (1) · Lapatinib (1) · N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl-6-(5-((methylsulfonyl)ethyl)aminomethyl)-2-furyl)-4-quinazolinamine (1) · fluorodopa F 18 (1) · gallium Ga 68 dotatate (1) · palbociclib (1)
National Cancer Institute (NCI) (2) · Pediatric Brain Tumor Consortium (2) · Erik Mittra (1) · Sue O'Dorisio (1)
United States (6) · Canada (1)
David Van Mater, MD (1) · Erik Mittra, MD, PhD (1) · M. Sue O'Dorisio, MD, PhD (1) · Mariko DeWire (1) · Maryam Fouladi (1) · Tobey MacDonald (1)
U01CA081457 (3), P30CA086862 (1), P30CA124435 (1), U10CA098543 (1)